3D Analysis of Cemento-Osseous Lesions

NCT ID: NCT04608708

Last Updated: 2020-10-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

46 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-10-22

Study Completion Date

2020-10-21

Brief Summary

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COD lesions effect a wide range of different anatomical areas, show different volume and morphometric characteristics.

Detailed Description

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Fibro-osseous lesions of the jaws are one of the important lesion groups for which identification and diagnosis create clinical difficulties. In previous studies, the features of the lesions and the effects of COD on anatomical structures were analysed via CBCT images by measuring the lesion's dimensions linearly for the first time in the Brazilian population. However, 3D measurements of the volume need to be taken to assess the actual spread over adjacent anatomical structures. The purpose of this retrospective study is to measure the volume of the lesions that have been diagnosed as COD in the Turkish population by using 3D images. This will contribute to an advanced study conducted on the global population to observe a change in these morphologies with respect to different geographical and ethnic origins.

Conditions

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Bone Diseases Cone-beam Computed Tomography Florid Cemento-osseous Dysplasia

Study Design

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Observational Model Type

CASE_CROSSOVER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Group 1. Periapical Cemento-Osseous Dysplasia

In Periapical Cemento-Osseous Dysplasia , the lower anterior teeth are usually affected. In these lesions, normal bone is replaced by fibrous tissue that contains amorphous vascularised calcifications. In the early stage, it can mimic a periapical lesion, but it is usually associated with vital teeth, without any clinical complaint, and it requires no intervention. Histopathologically, the lesion is similar to fibrous dysplasia and ossifying fibroma.

The data of patients who had applied to the clinic for various reasons and were diagnosed with fibro-osseous lesions

Intervention Type OTHER

lesions diagnosed radiologically and followed up for at least one year were included in this study with the help of cone beam computed tomography.

Group 2. Focal Cemento-Osseous Dysplasia

It occurs in a single area of the posterior teeth. Its radiographic and histolopathological features are similar to Periapical Cemento-Osseous Dysplasia

The data of patients who had applied to the clinic for various reasons and were diagnosed with fibro-osseous lesions

Intervention Type OTHER

lesions diagnosed radiologically and followed up for at least one year were included in this study with the help of cone beam computed tomography.

Grup 3. Florid Cemento-Osseous Dysplasia

When the lesions involve two or more quadrants of the jaw, it is defined as Florid Cemento-Osseous Dysplasia. Its radiographic and histolopathological features are similar to Periapical Cemento-Osseous Dysplasia

The data of patients who had applied to the clinic for various reasons and were diagnosed with fibro-osseous lesions

Intervention Type OTHER

lesions diagnosed radiologically and followed up for at least one year were included in this study with the help of cone beam computed tomography.

Interventions

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The data of patients who had applied to the clinic for various reasons and were diagnosed with fibro-osseous lesions

lesions diagnosed radiologically and followed up for at least one year were included in this study with the help of cone beam computed tomography.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* They were diagnosed with fibro-osseous lesions with the help of cone beam computed tomography between 2017 and 2020 were included in the study.
* The lesions diagnosed radiologically and followed up for at least one year were included in this study.

Exclusion Criteria

-Radiographs with insufficient diagnostic images were not included.
Eligible Sex

Accepts Healthy Volunteers

Yes

Sponsors

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Recep Tayyip Erdogan University Training and Research Hospital

OTHER

Sponsor Role lead

Responsible Party

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DİLARA NİL GÜNAÇAR

assistant professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Dilara Nil Günaçar

Role: PRINCIPAL_INVESTIGATOR

Recep Tayyip Erdogan University Training and Research Hospital

Locations

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Recep Tayyip Erdogan University Training and Research Hospital

Rize, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Kato CNAO, Barra SG, Amaral TMP, Silva TA, Abreu LG, Brasileiro CB, Mesquita RA. Cone-beam computed tomography analysis of cemento-osseous dysplasia-induced changes in adjacent structures in a Brazilian population. Clin Oral Investig. 2020 Aug;24(8):2899-2908. doi: 10.1007/s00784-019-03154-x. Epub 2020 Feb 19.

Reference Type BACKGROUND
PMID: 32076867 (View on PubMed)

Kato CN, Barra SG, Pereira MJ, Gomes LT, Amaral TM, Abreu LG, Brasileiro CB, Mesquita RA. Mandibular radiomorphometric parameters of women with cemento-osseous dysplasia. Dentomaxillofac Radiol. 2020 May 1;49(4):20190359. doi: 10.1259/dmfr.20190359. Epub 2019 Dec 20.

Reference Type BACKGROUND
PMID: 31846355 (View on PubMed)

Other Identifiers

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2020/189

Identifier Type: -

Identifier Source: org_study_id