Measuring the Impact of an Innovative Educational Intervention in Inflammatory Arthritis

NCT ID: NCT04606810

Last Updated: 2020-10-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

112 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-10-01

Study Completion Date

2019-10-07

Brief Summary

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Self-management is critical for patients with chronic conditions such as rheumatoid arthritis. Such management requires that patients understand what to do to best manage their condition. This study will use a randomized controlled study design to evaluate the impact of a new educational intervention consisting of an educational digital video disc (DVD) and a self-management support session/teleconference with a multidisciplinary team of health care providers for patients (n=150) with active rheumatoid arthritis (RA) starting on or changing biologic agents. This study aims to test whether this intervention improves behavioural intentions, knowledge, and medication adherence three months post-intervention and whether acquired knowledge is retained six months after the intervention. This project will allow to quantify the impact of the educational intervention on patients' behavioural intentions in practical situations using an existing validated questionnaire called BioSecure. The impact of the educational intervention on disease-specific knowledge and on medication adherence will be evaluated using validated questionnaires.

Detailed Description

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The primary objective of this study was to determine whether patients with active RA starting or changing biological agents demonstrate better self-care safety skills in practical situations using the BioSecure questionnaire three months after receiving a multidisciplinary educational intervention, as compared to patients who received usual care. The secondary objectives were to assess the impact of the educational intervention on behavioral intentions and beliefs and adherence to RA medications in patients receiving the intervention compared to usual care.

Trial design This was a pilot, unblinded, randomized study. Participants in group 1 received the usual care plus the multidisciplinary educational intervention at baseline. Participants in group 2 first received usual care, and after 3 months were offered the intervention. The patients' self-care safety skills was measured using the BioSecure questionnaire, and the behavioral intentions and beliefs with respect to medications was assessed using structured questionnaires at baseline, 3 and 6 months. With the participant authorization, data on RA medication adherence, i.e. biological agents and other non-biologic Disease-modifying anti-rheumatic drugs (nbDMARDs) was obtained for the 3 months preceding enrollment and up to 6 months afterwards using their pharmacy records.

Conditions

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Rheumatoid Arthritis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SEQUENTIAL

Participants in group 1 received the usual care plus the multidisciplinary educational intervention at baseline.

Participants in group 2 first received usual care, and after 3 months were offered the intervention.
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Arm1, Participants received the multidisciplinary educational intervention at baseline

Participants in arm1 received the usual care plus the multidisciplinary educational intervention consisting of an educational DVD followed by a teleconference at baseline.

Group Type ACTIVE_COMPARATOR

multidisciplinary educational intervention

Intervention Type OTHER

At randomization, participants in arm 1 received the educational DVD with the instruction to review its contents within the next two weeks. Between 2 and 4 weeks after randomization, reinforcement teleconferences were done in small groups of 10 participants maximum per session with every participant who mentioned having watched the DVD. Each participant attended only to one teleconference. Usual care consisted in regular follow-up with the treating rheumatologist and possibility of asking questions of the rheumatology nurse by phone.

Arm2, Participants in arm2 received the educational intervention after 3 months

Participants in group 2 first received usual care, and after 3 months were offered the multidisciplinary educational intervention.

Group Type OTHER

multidisciplinary educational intervention

Intervention Type OTHER

At randomization, participants in arm 1 received the educational DVD with the instruction to review its contents within the next two weeks. Between 2 and 4 weeks after randomization, reinforcement teleconferences were done in small groups of 10 participants maximum per session with every participant who mentioned having watched the DVD. Each participant attended only to one teleconference. Usual care consisted in regular follow-up with the treating rheumatologist and possibility of asking questions of the rheumatology nurse by phone.

Interventions

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multidisciplinary educational intervention

At randomization, participants in arm 1 received the educational DVD with the instruction to review its contents within the next two weeks. Between 2 and 4 weeks after randomization, reinforcement teleconferences were done in small groups of 10 participants maximum per session with every participant who mentioned having watched the DVD. Each participant attended only to one teleconference. Usual care consisted in regular follow-up with the treating rheumatologist and possibility of asking questions of the rheumatology nurse by phone.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* age ≥ 18 years and had a diagnosis of RA,
* with active disease as per rheumatologist evaluation,
* having received a trial of two traditional nbDMARDs therapy, and
* who requires the addition or change of a biological agent

Exclusion Criteria

* patient unable to consent,
* patient unable to answer questionnaires,
* patient unable to view a DVD at home
* patient unable to participate in a teleconference
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Canadian Rheumatology Association

OTHER

Sponsor Role collaborator

The Arthritis Society, Canada

OTHER

Sponsor Role collaborator

Laval University

OTHER

Sponsor Role collaborator

CISSS de Chaudière-Appalaches

OTHER_GOV

Sponsor Role collaborator

Clinique Rhumatologie/Physiatrie Centre du Québec, Trois-Rivières

UNKNOWN

Sponsor Role collaborator

Centre de Rhumatologie de l'Est du Québec

OTHER

Sponsor Role collaborator

CHU de Quebec-Universite Laval

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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MP-20-2015-2242

Identifier Type: -

Identifier Source: org_study_id