Time-in-range Using Continuous Glucose Monitoring Management of Gestational Diabetes Mellitus

NCT ID: NCT04605497

Last Updated: 2024-05-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

111 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-02-11

Study Completion Date

2023-12-31

Brief Summary

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The continual glucose is going to increase time-in-range compared to the standard method in women with gestational diabetes

Detailed Description

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Conditions

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Gestational Diabetes

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Intervention Arm

Use of Dexcom G6 real-time CGM to monitor blood glucose levels continually.

Group Type EXPERIMENTAL

Continuous glucose monitoring (CGM)

Intervention Type DIAGNOSTIC_TEST

Continual use of CGM to monitor blood glucose levels from enrollment through delivery admission \& discharge + additional 10 days during postpartum period

Referent Arm

Self-capillary blood glucose monitoring (SCBG) testing 4x/day with blinded CGM every 2 weeks.

Group Type OTHER

Self-Capillary Blood Glucose Monitoring (SCBG)

Intervention Type DIAGNOSTIC_TEST

Conventional SCBG 4x/day testing (standard care in Oregon; fasting and 1-hour postprandial) with blinded CGM every 2 weeks SCBG 4 times/day until delivery admission 10 days duration with each blinded CGM wear

Interventions

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Continuous glucose monitoring (CGM)

Continual use of CGM to monitor blood glucose levels from enrollment through delivery admission \& discharge + additional 10 days during postpartum period

Intervention Type DIAGNOSTIC_TEST

Self-Capillary Blood Glucose Monitoring (SCBG)

Conventional SCBG 4x/day testing (standard care in Oregon; fasting and 1-hour postprandial) with blinded CGM every 2 weeks SCBG 4 times/day until delivery admission 10 days duration with each blinded CGM wear

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Age 18-55 years
* Singleton pregnancy ≥20 weeks gestation
* Diagnosed with GDM by either 1-step (IADPSG) or 2-Step (Carpenter-Coustan)
* Compatible, validated phone and operating system to support Dexcom G6 CGM App (See Supplementary Table 1) or option to use receiver

Exclusion Criteria

* Chronic immunosuppression
* Concomitant disease or condition that may compromise patient safety or the ability to complete study tasks including and not limited to: severe mental illness or a diagnosed or suspected eating disorder
* Known allergy to medical grade adhesives
* Pre-gestational diabetes
* Multifetal gestation
* Current alcohol or illicit drug use
* Simultaneous participation in another clinical study with investigational medicinal product(s) that might have an impact on the study objectives.
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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DexCom, Inc.

INDUSTRY

Sponsor Role collaborator

Oregon Health and Science University

OTHER

Sponsor Role lead

Responsible Party

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Amy Miyoshi Valent

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Amy Valent

Role: PRINCIPAL_INVESTIGATOR

Oregon Health and Science University

Locations

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OHSU

Portland, Oregon, United States

Site Status

Countries

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United States

Other Identifiers

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STUDY00021775

Identifier Type: -

Identifier Source: org_study_id

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