Weight-Adjusted Dosing of 3-OHB in Patients With Chronic Heart Failure
NCT ID: NCT04594265
Last Updated: 2022-07-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
UNKNOWN
PHASE2
8 participants
INTERVENTIONAL
2020-10-01
2022-09-30
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Effects of Carnitine Supplementation on Liver and Muscle
NCT03439917
A Carbohydrate-restricted Diet to Reverse Fatty Liver in Adolescents With Obesity
NCT02787668
Effect of Bile Acids on Satiety, Cell Function and Body Weight in Patients With Obesity and Abnormal Satiety Phenotype
NCT05314374
Clinical Outcome of Triheptanoin Treatment in Patients With Long-chain Fatty Acid Oxidation Disorders (LC-FAOD) Treated Under Expanded Access Program
NCT03768817
Dietary Allowance of Methyl Donor Nutrients to Minimize Risks of Non-alcoholic Fatty Liver Progression
NCT05291104
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
CROSSOVER
TREATMENT
DOUBLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Ketone Monoester
Weight-adjusted dose of 3-OHB Monoester (KetoneAID KE4, Virginia, US) 0.5 g/kg (max 50 g)
KetoneAid KE4 Pro Monoester
A dietary supplement containing ketone monoester.
Placebo Treatment
Maltodextrin-based placebo (Science In Sport, UK) in isocaloric dose to the experimental arm.
Science in Sport Go Enegy
Dosis isocaloric to the KetoneAid Arm
Ketone Monoester in presence of low-dose insulin clamp
Same as experimental arm, but in the presence of a low-dose insulin clamp to suppress free fatty acid metabolism
KetoneAid KE4 Pro Monoester
A dietary supplement containing ketone monoester.
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
KetoneAid KE4 Pro Monoester
A dietary supplement containing ketone monoester.
Science in Sport Go Enegy
Dosis isocaloric to the KetoneAid Arm
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
Exclusion Criteria: Diabetes or HbA1c \>48 mmol/mol, significant cardiac valve disease, severe stable angina pectoris, severe comorbidity as judged by the investigator, inability to give informed consent
18 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
University of Aarhus
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Kristian Hylleberg Christensen
MD
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Aarhus University Hospital
Aarhus, , Denmark
Countries
Review the countries where the study has at least one active or historical site.
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Henrik S Wiggers, DMsci
Role: CONTACT
Facility Contacts
Find local site contact details for specific facilities participating in the trial.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
KETO-KINETICS 2 1-10-72-23-20
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.