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Influence of Inguinal Hernia Repair on Sperm Autoimmunity

NCT ID: NCT04591470

Last Updated: 2020-11-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

2415 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-06-01

Study Completion Date

2020-10-01

Brief Summary

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Influence of inguinal hernia repair on sperm autoimmunity using MAR test

Detailed Description

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All infertile male patients, visited between February 2000 and September 2020 and which were tested with MAR (Mixed Autoglobulin Reaction) test, were included in this retrospective study. Sperm quality (number of spermatozoa, motility, vitality and normal forms) were also studied in this patients. The aim of the study is to evaluate if there is a higher incidence of positive MAR test among patients undergoing inguinal hernioplasty compared to the general population

Conditions

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Male Infertility Due to Antisperm Antibody

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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General population

Mar test

Intervention Type DIAGNOSTIC_TEST

Study of antisperm antibodies

Pazients undergone inguinal hernia correction

Mar test

Intervention Type DIAGNOSTIC_TEST

Study of antisperm antibodies

Interventions

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Mar test

Study of antisperm antibodies

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Patients undergone to correction of inguinal hernia
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Istituto Clinico Humanitas

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Istituto Clinico Humanitas

Rozzano, Milano, Italy

Site Status

Countries

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Italy

References

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Gupta S, Krishna A, Jain M, Goyal A, Kumar A, Chaturvedi P, Sagar R, Ramachandran R, Prakash O, Kumar S, Seenu V, Bansal V. A three-arm randomized study to compare sexual functions and fertility indices following open mesh hernioplasty (OMH), laparoscopic totally extra peritoneal (TEP) and transabdominal preperitoneal (TAPP) repair of groin hernia. Surg Endosc. 2021 Jun;35(6):3077-3084. doi: 10.1007/s00464-020-07697-z. Epub 2020 Jun 15.

Reference Type BACKGROUND
PMID: 32556769 (View on PubMed)

Stula I, Druzijanic N, Sapunar A, Perko Z, Bosnjak N, Kraljevic D. Antisperm antibodies and testicular blood flow after inguinal hernia mesh repair. Surg Endosc. 2014 Dec;28(12):3413-20. doi: 10.1007/s00464-014-3614-7. Epub 2014 Jun 25.

Reference Type BACKGROUND
PMID: 24962853 (View on PubMed)

Matsuda T, Hiura Y, Muguruma K, Okuno H, Horii Y, Yoshida O. Quantitative analysis of testicular histology in patients with vas deferens obstruction caused by childhood inguinal herniorrhaphy: comparison to vasectomized men. J Urol. 1996 Feb;155(2):564-7.

Reference Type BACKGROUND
PMID: 8558661 (View on PubMed)

Other Identifiers

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64/20

Identifier Type: -

Identifier Source: org_study_id