Prevention of Cardiovascular Diseases Caused by Complex Treatment of Patients With Primary Operated Breast Cancer

NCT ID: NCT04588935

Last Updated: 2023-02-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-07-01

Study Completion Date

2023-02-07

Brief Summary

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To develop a method of medical prevention of cardiovascular diseases caused by cardiotoxicity against the background of complex treatment of patients with primary resectable breast cancer to reduce the risk of cardiovascular complications

Detailed Description

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Purpose of the study: to develop a method of medical prevention of cardiovascular diseases caused by cardiotoxicity against the background of complex treatment of patients with primary resectable breast cancer to reduce the risk of cardiovascular complications

Conditions

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Women With Breast Cancer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Group 1

women with breast cancer, with a morphologically confirmed diagnosis before the appointment of anticancer therapy, untreated

Group Type NO_INTERVENTION

No interventions assigned to this group

Group 2

women with breast cancer, with a morphologically confirmed diagnosis before the appointment of anticancer therapy, receiving treatment with a combination of bisoprolol and perindopril

Group Type ACTIVE_COMPARATOR

Bisoprolol; Perindopril;

Intervention Type DRUG

based on the results of the patient study, different drug therapy regimens for cardiovascular complications during chemotherapy will be proposed

Interventions

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Bisoprolol; Perindopril;

based on the results of the patient study, different drug therapy regimens for cardiovascular complications during chemotherapy will be proposed

Intervention Type DRUG

Other Intervention Names

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Bisoprolol; Perindopril

Eligibility Criteria

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Inclusion Criteria

* women with breast cancer, with a morphologically confirmed diagnosis before the appointment of anticancer therapy.

Exclusion Criteria

* presence of other oncological diseases
Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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State Institution "Republican Scientific and Practical Center" Cardiology, Belarus

OTHER

Sponsor Role lead

Responsible Party

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Dr. Chernyak Sergey

Researcher, Hypertension Laboratory Republican Scientific and Clinical Cardiology Center Republic of Belarus, Belarus

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Scientific and Practice Center of Cardiology

Minsk, , Belarus

Site Status

Countries

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Belarus

Other Identifiers

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20192755

Identifier Type: -

Identifier Source: org_study_id

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