Treatment With Bempedoic Acid and/or Its Fixed-dose Combination With Ezetimibe in Primary Hypercholesterolemia or Mixed Dyslipidemia

NCT ID: NCT04579367

Last Updated: 2025-11-18

Basic Information

• Recruitment Status: ACTIVE_NOT_RECRUITING
• Total Enrollment: 5000 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2021-01-15
• Study Completion Date: 2026-10-30

Brief Summary

The primary objective is to describe in the real-world setting patient characteristics and outcomes of patients with primary hypercholesterolaemia (heterozygous familial and non-familial) or mixed dyslipidaemia using bempedoic acid and/or its fixed-dose combination with ezetimibe in managing plasma levels of low-density lipoprotein cholesterol (LDL-C).

Secondary objectives are to document and evaluate as applicable:

• Assessment of the cardiovascular risk of patients treated with bempedoic acid and/or its fixed-dose combination with ezetimibe using different risk scores (e.g. Systematic Coronary Risk Estimation (SCORE) system, SMART score for Very High Risk patients and Framingham risk score for High Risk patients. The scores will be re-calculated during the analysis and used as an analytical tool only).
• Changes in low-density lipoprotein cholesterol (LDL-C) levels prior to treatment with bempedoic acid and/or its fixed-dose combination with ezetimibe compared to 1 year follow-up and subsequent data collection points, if applicable.
• Characterize plasma levels of other potentially ASCVD-modifying cholesterol fragments, namely, LDL-C, total cholesterol (TC), apolipoprotein B (apoB), high-density lipoprotein cholesterol (HDL-C), non-HDL-C, triglycerides (TGs) and lipoprotein A (Lp[a]) compared to 1 year follow-up and subsequent data collection points, if applicable.
• Changes in the levels of inflammatory marker hsCRP compared to 1 year follow-up and subsequent data collection points, if applicable.
• Adverse Drug Reactions associated to bempedoic acid and/or its fixed-dose combination with ezetimibe.
• Changes in uric acid levels compared to 1 year follow-up and subsequent data collection points, if applicable.
• Relevant CV events:

• Myocardial infarction
• Unstable angina
• Coronary artery bypass graft surgery (CABG)
• Percutaneous transluminal coronary angioplasty (PTCA)
• Stroke
• Transient ischemic attack (TIA)
• Acute peripheral arterial occlusion
• All-cause death
• Cardiovascular (CV)-death
• Adverse effects associated with lipid-modifying treatment (LMT)

• Laboratory abnormalities
• Muscle-associated symptoms
• New onset and/or worsening diabetes
• Changes in the patients´ glycemic status over time
• Site characteristics (sites and practitioners) caring for patients treated with bempedoic acid and/or its fixed-dose combination with ezetimibe.
• Use of LMTs prior or concomitantly to receiving bempedoic acid and/or its fixed-dose combination with ezetimibe (therapies including combination treatments).
• Bempedoic acid and/or its fixed-dose combination with ezetimibe treatment parameters such as treatment duration by therapy, dosage, prescription intervals, permanent discontinuations, switches and reasons for these, (concomitant medication, additional therapy/interventions).
• Healthcare resource use especially consultation visits with specialist, nurse time and hospitalizations as well as patient-reported outcome using EQ-5D-5L and PAM-13.

Detailed Description

This non-interventional study will be conducted to characterize the risks and benefits of bempedoic acid and/or its fixed-dose combination with ezetimibe in a real-world clinical setting in adult patients with primary hypercholesterolaemia or mixed dyslipidaemia and to gain insight into the effectiveness (managing plasma levels of low-density lipoprotein cholesterol) as well as safety (clinical events associated with the treatment modalities). Real world evidence will be collected in 5000 participants, treated by specialized as well as non-specialized physicians in hospitals and office based centers.

Conditions

Hypercholesterolemia; Mixed Dyslipidemia

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Bempedoic acid and/or fixed-dose combination with ezetimibe

Participants with primary hypercholesterolemia or mixed dyslipidemia who received bempedoic acid and/or its fixed-dose combination with ezetimibe.

Bempedoic acid and/or its fixed-dose combination with ezetimibe

Intervention Type: DRUG

This is a non-interventional study. No study medication will be provided to the patients. Medication will be prescribed by the treating physician in line with the clinical practice.

Interventions

Bempedoic acid and/or its fixed-dose combination with ezetimibe

This is a non-interventional study. No study medication will be provided to the patients. Medication will be prescribed by the treating physician in line with the clinical practice.

Intervention Type: DRUG

Eligibility Criteria

Inclusion Criteria

• Written informed consent to participate
• At least 18 years of age
• Participants suffering from documented primary hypercholesterolemia or mixed dyslipidemia treated or intended to be treated with bempedoic acid and/or its fixed dose combination with ezetimibe at the discretion of the physician are appropriate for participation in the observation.
• No contraindications exist according to the SmPC of bempedoic acid and/or its fixed-dose combination with ezetimibe
• No concurrent participation in an interventional study (simultaneous participation in other non-interventional study is possible)
• Life expectancy > 1 year

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

INDUSTRY

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Global Clinical Leader

Role: STUDY_DIRECTOR

Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Locations

Dr. Armin Öhlinger Kardiologe & innere Medizin

Dornbirn, , Austria

Landeskrankenhaus Feldkirch

Feldkirch, , Austria

LKH-Univ. Klinikum Graz

Graz, , Austria

Medizinische Universität Graz

Graz, , Austria

Internist Dr. med. univ. Stefan Moser

Hörsching, , Austria

Medizinische Universität Innsbruck

Innsbruck, , Austria

KABEG Klinikum Klagenfurt am Wörthersee

Klagenfurt, , Austria

Konventhospital der Barmherzigen Brüder Linz

Linz, , Austria

Ordination Dr. Johannes Föchterle

Linz, , Austria

Ordination Frau Prof. Dr. Yvonne Winhofer-Stöckl

Mattersburg, , Austria

Kompetenz-Zentrum Diabetes

Salzburg, , Austria

Ordination Universitätsdozent Dr. Alexander Kober

Sankt Aegyd am Neuwalde, , Austria

Ordination Dr. med. univ. Evelyn Fließer-Görzer

Sankt Stefan ob Stainz, , Austria

Ordination Dr. Thomas Maca

Vienna, , Austria

Klinik Hietzing, Wiener Gesundheitsverbund

Vienna, , Austria

Zentrum für Klinische Studien Dr. Hanusch GmbH

Vienna, , Austria

Allgemeines Krankenhaus der Stadt Wien

Vienna, , Austria

Univ.-Prof. Dr. Thomas Stulnig

Vienna, , Austria

Herz Zentrum Währing

Vienna, , Austria

Karl Landsteiner Institut für kardiovaskuläre und intensivmedizinische Forschung

Vienna, , Austria

ASZ

Aalst, , Belgium

Clinique Saint-Luc Bouge Namur

Bouge, , Belgium

Epicura Hornu

Boussu, , Belgium

A.Z. KLINA Brasschaat

Brasschaat, , Belgium

Clinique Saint-Jean Bruxelles

Brussels, , Belgium

CHU Brugman

Brussels, , Belgium

CUB-Hôpital Erasme

Brussels, , Belgium

UZ Brussel

Brussels, , Belgium

Clinique de l'Europe Saint Elisabeth

Brussels, , Belgium

UCL Saint-Luc Woluwé Bruxelles

Brussels, , Belgium

Private Practice

Ciney, , Belgium

Az Sint Blazius

Dendermonde, , Belgium

UZ Antwerpen

Edegem, , Belgium

Z.O.L - Campus St. Jan

Genk, , Belgium

AZ St-Lucas & Volkskliniek

Ghent, , Belgium

UZ Gent

Ghent, , Belgium

GHDC Charleroi - Site Hôpital Saint-Joseph

Gilly, , Belgium

Private Practice

Gribomont, , Belgium

Pôle hospitalier Jolimont

Haine-Saint-Paul, , Belgium

BVBA Med Kab

Halen, , Belgium

Jessa Ziekenhuis

Hasselt, , Belgium

CHR Huy

Huy, , Belgium

JAN YPERMAN Ziekenhuis

Ieper, , Belgium

AZ Groeninge Kortrijk

Kortrijk, , Belgium

CHU Tivoli

La Louvière, , Belgium

UZ Leuven

Leuven, , Belgium

CHR Citadelle de Liège

Liège, , Belgium

CHU Liège

Liège, , Belgium

CHU Charleroi Hopital civil Marie-Curie

Lodelinsart, , Belgium

CHU Mons Ambroise Paré

Mons, , Belgium

AZ Sint Jan

Ostend, , Belgium

AZ Delta

Roeselare, , Belgium

AZ Glorieux

Ronse, , Belgium

Sint Trudo

Sint-Truiden, , Belgium

Sint-Andriesziekenhuis Tielt

Tielt, , Belgium

CHU UCL Mont-Godinne

Yvoir, , Belgium

Downtown Clinic Aachen

Aachen, , Germany

Praxis Delonge

Aachen, , Germany

Praxis Osterziel

Amberg, , Germany

MVZ Helios Aue

Aue, , Germany

Kardiologische Praxis Enders

Bad Elster, , Germany

SLK-Klinikum am Plattenwald

Bad Friedrichshall, , Germany

Herzcarre Praxis

Bad Homburg, , Germany

Kardiologische Praxis

Bad Homburg, , Germany

Zentrum für klinische Forschung

Bad Homburg, , Germany

Universitätsklinikum Freiburg - Universitäts-Herzzentrum

Bad Krozingen, , Germany

Praxis am Landratspark

Bad Segeberg, , Germany

Hausärzte am Spritzenhaus

Baiersbronn, , Germany

CIMS Studienzentrum Bamberg GmbH Drs. Kirschner/Haas/Ritzel

Bamberg, , Germany

Kardiologische Praxis

Bechhofen, , Germany

Praxis Rankestraße

Berlin, , Germany

SKP Studienzentrum der kardiologischen Praxisgemeinschaft Rankestrasse GmbH

Berlin, , Germany

Herzpraxis Berlin MVZ

Berlin, , Germany

Charité - Universitätsmedizin Berlin

Berlin, , Germany

Dres. Seeger & Partner

Berlin, , Germany

Diabetespraxis Dr. Braun

Berlin, , Germany

Lipidambulanz Charite

Berlin, , Germany

Praxiszentrum Biedenkopf

Biedenkopf, , Germany

Praxis Dr. A. Biedermann

Blankenhain, , Germany

Kardiologische Gemeinschaftspraxis Bremerhaven

Bremerhaven, , Germany

Kardiologie im Friedrichspalast Bruchsal

Bruchsal, , Germany

MediClin Reha-Zentrum Spreewald

Burg, , Germany

Studiengesellschaft Könemann und Steinmann GbR

Bünde, , Germany

MVZ am Küchwald

Chemnitz, , Germany

Kardiologische Praxis Stellmach

Chemnitz, , Germany

MVZ Polymed

Chemnitz, , Germany

Uniklinik Köln

Cologne, , Germany

Zentrum für klinische Forschung

Cologne, , Germany

IKAPP

Cologne, , Germany

Praxis Dr. Menzel

Dessau, , Germany

Klinikum Lippe GmbH

Detmold, , Germany

Kardiologische Gemeinschaftspraxis

Dortmund, , Germany

Cardiologicum Dresden/Pirna

Dresden, , Germany

Hausärztliche Gemeinschaftspraxis mit diabetologischem Schwerpunkt

Dresden, , Germany

Dres. Günther/Kolschmann

Dresden, , Germany

Herzzentrum Dresden, Universitätsklinik an der Technischen Universität Dresden

Dresden, , Germany

Universitätsklinikum Carl Gustav Carus

Dresden, , Germany

DZDM Diabeteszentrum Duisburg Mitte

Duisburg, , Germany

Nierenzentrum Düren

Düren, , Germany

Universitätsklinikum Düsseldorf

Düsseldorf, , Germany

Praxis Dilltal

Ehringshausen, , Germany

Praxis Dipl. -Med. Petra Herrmann

Eisenach, , Germany

Kardiologische Praxis

Elsterwerda, , Germany

Gemeinschaftspraxis ISP Erlangen

Erlangen, , Germany

Hausarztzentrum am Germaniaplatz

Essen, , Germany

DIAKO Flensburg

Flensburg, , Germany

Praxis für Nieren und Hochdruck-Krankheiten

Flensburg, , Germany

MVZ Altstadt-Carree Fulda

Fulda, , Germany

Klinikum Fulda

Fulda, , Germany

Praxis Dr. Langel

Gera, , Germany

Cardiocampus Gemeinschaftspraxis für Herz- und Kreislauferkrankungen

Gifhorn, , Germany

Praxis für Gefäßmedizin

Görlitz, , Germany

Universitätsmedizin Göttingen

Göttingen, , Germany

Praxis Dr. Müller

Gräfenhainichen, , Germany

Universitätsmedizin Greifswald

Greifswald, , Germany

Evangelisches Krankenhaus Hagen-Haspe

Hagen, , Germany

Praxis

Hainburg, , Germany

Cardiologicum Hamburg - Praxis Wandsbek

Hamburg, , Germany

Diabetes Zentrum Wandsbeck

Hamburg, , Germany

MVZ Prof. Mathey, Prof. Schofer

Hamburg, , Germany

Kardiologie am Tibarg

Hamburg, , Germany

Kardiologie List

Hanover, , Germany

Kardiologische Praxis

Hanover, , Germany

Kardiologische Praxis

Haßloch, , Germany

Kardiologische Schwerpunktpraxis

Heidelberg, , Germany

Universitätsklinikum Heidelberg

Heidelberg, , Germany

Praxis Heik/Wedig

Heiligenstadt, , Germany

KARDIO-IN Kardiologische Gemeinschaftspraxis

Ingolstadt, , Germany

Kardiologische Praxis

Kaiserslautern, , Germany

SRH Klinikum Karlsbad-Langensteinbach

Karlsbad, , Germany

B. Braun Ambulantes Herzzentrum Kassel

Kassel, , Germany

Praxis Dr. Heiner Müller

Katzhütte, , Germany

Nephrologie Kiel

Kiel, , Germany

Gemeinschaftsklinikum Mittelrhein

Koblenz, , Germany

Studienzentrum der Inneren Medizin I & II am Klinikum Konstanz

Konstanz, , Germany

Kardiologie Dr. med. E. Persicke / Dr. med. O. Scheuermann

Kornwestheim, , Germany

Kardiologische Praxis Kyritz

Kyritz, , Germany

Universitätsklinikum Leipzig

Leipzig, , Germany

Kardiologische Praxis Boudriot

Leipzig, , Germany

MVZ Stoffwechselmedizin Leipzig

Leipzig, , Germany

Praxis Dr. I.Simon-Wagner

Lichtenfels, , Germany

St. Vincenz Krankenhaus

Limburg, , Germany

Gemeinschaftspraxis Dr. Jens Biesenbaum und Dr. Uwe Gerbaulet

Löhne, , Germany

Cardio Centrum Ludwigsburg-Bietigheim

Ludwigsburg, , Germany

Kardiologische Praxisklinik Ludwigshafen

Ludwigshafen, , Germany

Universität zu Lübeck

Lübeck, , Germany

Institut für Präventive Medizin & Klinische Forschung GbR

Magdeburg, , Germany

Cardiopraxis Mainz

Mainz, , Germany

Katholisches Klinikum Mainz

Mainz, , Germany

Universitätsklinikum Mainz

Mainz, , Germany

ZE:RO Praxen

Mannheim, , Germany

UMM Mannheim

Mannheim, , Germany

Kardiologische Praxis

Markkleeberg, , Germany

Praxis Ben-Chur

Meiningen, , Germany

Praxis Haj-Yehia

Moers, , Germany

Gemeinschaftspraxis Dr. Prohaska/Dr. Schulte

Mühldorf, , Germany

Kardiologie Mühldorf am Inn

Mühldorf, , Germany

Herzquartier Mülheim

Mülheim, , Germany

Kardiologie Neuhausen-Nymphenburg

München, , Germany

Dres. Wauer/Windstetter

München, , Germany

Praxis Kiepenkerl

Münster, , Germany

Zentrum für Kardiologie an der Raphaelsklinik Münster

Münster, , Germany

Praxis für Innere Medizin Münster

Münster, , Germany

Universitätsklinikum Münster

Münster, , Germany

Internistische Praxisgemeinschaft

Neu-Isenburg, , Germany

Kardiologische Praxis Northeim

Northeim, , Germany

Hausarztpraxis

Oer-Erkenschwick, , Germany

St. Vincenz-Krankenhaus GmbH

Paderborn, , Germany

Kardiologische Praxis Papenburg - Site 6071

Papenburg, , Germany

Kardiologische Praxis Papenburg - Site 6072

Papenburg, , Germany

Gemeinschaftspraxis Dres. med. Karl-Heinz Göttl - Omar Adjan

Passau, , Germany

Hausärztlich-Kardiologisches MVZ "Am Felsenkeller" GmbH

Pirna, , Germany

Kinikum Ernst von Bergmann

Potsdam, , Germany

VieSante Herzmedizin Potsdam

Potsdam, , Germany

Kardiologische Gemeinschaftspraxis

Potsdam, , Germany

Allgemeinmedizinisch Internistische Praxis Dr. H. Borgmann

Radebeul, , Germany

Internistisch hausärtzliche Gemeinschaftspraxis Dr. Hildebrandt & Dr. Mutscher

Radebeul, , Germany

Gemeinschaftspraxis Herz Riesa

Riesa, , Germany

Universitätsmedizin Rostock

Rostock, , Germany

Facharztpraxis für Kardiologie und Innere Medizin

Schwäbisch Hall, , Germany

MVZ Schwerin West GmbH

Schwerin, , Germany

Nierenzentrum Altmark

Seehausen, , Germany

Zentrum für Prävention und Rehabilitation

Siegen, , Germany

Klinik Singen

Singen, , Germany

MEDINOS Klinik Sonneberg

Sonneberg, , Germany

Kardiologische Praxis im Steiner Thor

Straubing, , Germany

Praxis Dr Knöbel u. Partner

Straubing, , Germany

Praxis Dr. Michael Rother

Strausberg, , Germany

Diabetologische Schwerpunktpraxis

Trier, , Germany

Krankenhaus der Barmherzigen Brüder Trier

Trier, , Germany

Studienzentrum der Herzklinik Ulm GbR

Ulm, , Germany

Praxis Dr. Hansen

Unterwellenborn, , Germany

Praxis Dr. Dengler/Hohenstatt

Ursensollen, , Germany

Herzzentrum Saar

Völklingen, , Germany

GRN Weinheim

Weinheim, , Germany

Kardiologische Praxis Al-Zoebi

Wermsdorf, , Germany

Internistische Gemeinschaftspraxis Dr. med. Schreckenberg, Dr. med. Vorderstraße

Weyhe, , Germany

Forschungszentrum-Ruhr / KliFoCenter GmbH

Witten, , Germany

Kardiologische Praxis Tamm/Hoh

Wittenberg, , Germany

Kardiologische Fachpraxis

Wolmirstedt, , Germany

Zentrum für Nieren- und Hochdrucklerkrankungen Hofaue

Wuppertal, , Germany

Universitätsklinikum Würzburg

Würzburg, , Germany

Gemeinschaftspraxis am Angerbrunnen

Zwiesel, , Germany

Ospedale Generale Regionale "F. Miulli"

Acquaviva delle Fonti, , Italy

P.O. Agrigento Ospedale San Giovanni di Dio

Agrigento, , Italy

IRCCS-INRCA Ancona

Ancona, , Italy

Ospedale di Anzio

Anzio, , Italy

Ospedale dei Castelli

Ariccia, , Italy

Ospedale "C. e G. Mazzoni"

Ascoli Piceno, , Italy

A.O. San Giuseppe Moscati

Avellino, , Italy

Ospedale SS Nicola e Filippo

Avezzano, , Italy

Ospedale S. Paolo

Bari, , Italy

A.O.U. Consorziale - Policlinico Bari

Bari, , Italy

Azienda Universitaria Ospedaliera Consorziale - Policlinico di Bari - Site 08016

Bari, , Italy

Azienda Universitaria Ospedaliera Consorziale - Policlinico di Bari - Site 08017

Bari, , Italy

AUSL Bologna Ospedale di Bentivoglio

Bentivoglio, , Italy

ASST Papa Giovanni XXIII

Bergamo, , Italy

Ospedale Maggiore Carlo Alberto Pizzardi

Bologna, , Italy

Policlinico Sant'Orsola Bologna-Malpighi

Bologna, , Italy

Ospedale di Bolzano - Site 08070

Bolzano, , Italy

Ospedale di Bolzano - Site 08112

Bolzano, , Italy

Spedali Civili di Brescia

Brescia, , Italy

Ospedale Santo Spirito Casale Monferrato

Casale Monferrato, , Italy

A.O. S. Anna e S. Sebastiano

Caserta, , Italy

ULLS 2 MARCA TREVIGIANA Ospedale di Castelfranco Veneto

Castelfranco Veneto, , Italy

AOU Policlinico Vittorio Emanuele Presidio Ospedaliero Gaspare Rodolico

Catania, , Italy

Azienda Ospedaliera Cannizzaro

Catania, , Italy

L'Azienda Ospedaliero-Universitaria "Renato Dulbecco" di Catanzaro

Catanzaro, , Italy

Ospedale Civile Santa Maria Incoronata dell'Olmo

Cava de' Tirreni, , Italy

Policlinico SS. Annunziata

Chieti, , Italy

ASL TO4 Presidio Riunito di Ciriè-Lanzo

Cirié, , Italy

Azienda Ospedaliero-Universitaria di Ferrara "Arcispedale Sant'Anna"

Cona, , Italy

Ospedale San Salvatore

Coppito, , Italy

Ospedale Santa Maria Nuova

Florence, , Italy

AOU Careggi - Site 08067

Florence, , Italy

AOU Careggi - Site 08081

Florence, , Italy

AOU Careggi - Site 08090

Florence, , Italy

Azienda Ospedaliera Universitaria "Ospedali Riuniti" di Foggia

Foggia, , Italy

Ospedale Policlinico San Martino

Genova, , Italy

Presidio Ospedaliero S.O. Padre Antero Micone

Genova, , Italy

Ospedale della Misericordia

Grosseto, , Italy

Ospedale Sant'Andrea

La Spezia, , Italy

ASP Catanzaro Presidio Ospedaliero "Giovanni Paolo II"

Lamezia Terme, , Italy

Ospedale Vito Fazzi

Lecce, , Italy

Ospedale Mater Salutis

Legnago, , Italy

Presidio Ospedaliero "Madonna delle Grazie"

Matera, , Italy

Presidio ospedaliero San Giovanni di Dio

Melfi, , Italy

A.O.U. Policlinico "G. Martino"

Messina, , Italy

ULSS 3 SERENISSIMA Ospedale dell'Angelo

Mestre, , Italy

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico - Site 08039

Milan, , Italy

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico - Site 08097

Milan, , Italy

Centro Cardiologico Monzino

Milan, , Italy

Ospedale San Luca - Gruppo Istituto Auxologico Italiano

Milan, , Italy

ASST Grande Ospedale Metropolitano Niguarda

Milan, , Italy

Ospedale Niguarda

Milan, , Italy

ULSS 3 Serenissima Presidio Ospedaliero di Mirano

Mirano, , Italy

AOU Modena Policlinico Modena

Modena, , Italy

A.O.R.N. Antonio Cardarelli

Napoli, , Italy

A.O.R.N. MONALDI OSPEDALE DEI COLLI Ospedale Monaldi

Napoli, , Italy

A.O.U. Federico Ii

Napoli, , Italy

Azienda Ospedaliera Specialistica dei Colli Ospedale Monaldi

Napoli, , Italy

Policlinico Università Federico II - Napoli

Napoli, , Italy

Ospedale Umberto I

Nocera Inferiore, , Italy

AOU Maggiore della Carità di Novara

Novara, , Italy

Ospedale San Giacomo

Novi Ligure, , Italy

Azienda ospedaliera-Università di Padova

Padua, , Italy

A.O.U. Policlinico "P. Giaccone"

Palermo, , Italy

Casa di Cura Triolo Zancla Hospital

Palermo, , Italy

ICS Maugeri

Pavia, , Italy

USL Umbria I

Perugia, , Italy

Azienda Ospedaliera S. Maria della Misericordia di Perugia

Perugia, , Italy

Ospedale Guglielmo da Saliceto

Piacenza, , Italy

Fondazione Monasterio

Pisa, , Italy

P. O. Portogruaro

Portogruaro, , Italy

Azienda Ospedaliera Regionale San Carlo di Potenza

Potenza, , Italy

Nuovo Ospedale Santo Stefano

Prato, , Italy

Azienda Sanitaria Provinciale di Ragusa Ospedale Giovanni Paolo II

Ragusa, , Italy

Ospedale Santa Maria delle Croci

Ravenna, , Italy

ASST Rhodense - Ospedale di Circolo di Rho

Rho, , Italy

Ospedale San Camillo De Lellis

Rieti, , Italy

Ospedale Infermi AUSL Romagna

Rimini, , Italy

Ospedale degli Infermi di Rivoli

Rivoli, , Italy

Policlinico Tor Vergata

Roma, , Italy

Ospedale Sandro Pertini

Roma, , Italy

Policlinico Umberto I

Roma, , Italy

Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Site 08046

Roma, , Italy

Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Site 08121

Roma, , Italy

Policlinico Casilino

Roma, , Italy

AOU S. Andrea

Roma, , Italy

A.O. San Giovanni di Dio e Ruggi D'Aragona

Salerno, , Italy

ASST Valle Olona P.O. Saronno

Saronno, , Italy

Ospedale S. Bartolomeo

Sarzana, , Italy

AOU Sassari Ospedale SS. Annunziata

Sassari, , Italy

IRCCS Multimedica

Sesto San Giovanni, , Italy

A.O.U. Senese Ospedale Santa Maria alle Scotte

Siena, , Italy

AOU Senese- Policlinico Le Scotte

Siena, , Italy

Casa di cura Villa Verde

Taranto, , Italy

Azienda Ospedaliera Santa Maria

Terni, , Italy

Ospedale Mauriziano Presidio Umberto I

Torino, , Italy

AOU Ospedali Riuniti di Ancona

Torrette, , Italy

Ospedale Santa Chiara

Trento, , Italy

ULLS 2 MARCA TREVIGIANA Ospedale Ca' Foncello

Treviso, , Italy

Ospedale di Cattinara

Trieste, , Italy

Ospedale Santa Maria della Misericordia

Udine, , Italy

Ospedale Santa Maria della Misericordia

Urbino, , Italy

ASST Settelaghi Ospedale di Circolo e Fondazione Macchi

Varese, , Italy

Ospedale Castelli Verbania

Verbania, , Italy

ZGT

Almelo, , Netherlands

Meander Mc

Amersfoort, , Netherlands

AUMC

Amsterdam, , Netherlands

Mc Leeuwarden

Amsterdam, , Netherlands

Rijnstate

Arnhem, , Netherlands

AMPHIA

Breda, , Netherlands

Albert Schweitzer

Dordrecht, , Netherlands

ZGV

Ede, , Netherlands

Maxima Medisch Centrum

Eindhoven, , Netherlands

GHZ

Gouda, , Netherlands

Spaarne Gasthuis

Haarlem, , Netherlands

Saxenburgh Medisch Centrum

Hardenberg, , Netherlands

Tergooi Mc

Hilversum, , Netherlands

Treant Bethesda Hoogeveen

Hoogeveen, , Netherlands

Dijklander

Hoorn, , Netherlands

ALRIJNE

Leiderdorp, , Netherlands

MUMC+

Maastricht, , Netherlands

Erasmus Mc

Rotterdam, , Netherlands

Franciscus Gasthuis

Rotterdam, , Netherlands

MAASSTAD

Rotterdam, , Netherlands

Isala Zwolle

Zwolle, , Netherlands

Hospital General de Albacete

Albacete, , Spain

Hospital Universitario Fundación Alcorcón

Alcorcón, , Spain

Hospital Virgen de los Lirios

Alcoy, , Spain

Hospital General Universitario Dr. Balmis

Alicante, , Spain

Hospital Universitario Torrecárdenas

Almería, , Spain

Hospital Universitario Central de Asturias

Asturias, , Spain

Clínica Mapfre Salud Gijón

Asturias, , Spain

Hospital Universitario San Agustin

Asturias, , Spain

Hospital Vital Álvarez-Buylla

Asturias, , Spain

Hospital Universitario Nuestra Señora del Perpetuo Socorro

Badajoz, , Spain

Hospital Universitario de Cruces

Barakaldo, , Spain

Hospital de Bellvitge

Barcelona, , Spain

Hospital Universitario de Basurto

Bilbao, , Spain

Hospital Universitario de Burgos

Burgos, , Spain

Hospital Universitario Puerta del Mar

Cadiz, , Spain

Hospital General Universitario de Castellón

Castellon, , Spain

Hospital Universitario San Pedro de Alcántara

Cáceres, , Spain

Hospital del Henares

Coslada, Madrid, , Spain

Hospital Universitario Reina Sofía

Córdoba, , Spain

Hospital de Denia

Denia, , Spain

Hospital UNiversitario de Donostia

Donostia / San Sebastian, , Spain

Hospital de Fuenlabrada

Fuenlabrada Madrid, , Spain

Hospital Universitario de Cabueñes

Gijón, , Spain

Hospital Universitario Virgen de las Nieves

Granada, , Spain

Hospital Universitario San Cecilio

Granada, , Spain

Hospital Universitario Juan Ramón Jiménez

Huelva, , Spain

Hospital Universitario Médico-Quirúrgico de Jaén

Jaén, , Spain

Hospital Jerez de la Frontera

Jerez de La Frontera, Cádiz, , Spain

Hospital Universitario de Gran Canaria Dr. Negrín

Las Palmas de Gran Canaria, , Spain

Complejo Hospitalario Universitario Insular Materno-Infantil de Gran Canaria

Las Palmas de Gran Canaria, , Spain

Hospital Universitario de León

León, , Spain

Hospital San Pedro

Logroño, , Spain

Hospital Universitario la Princesa

Madrid, , Spain

Hospital Universitario Gregorio Marañón

Madrid, , Spain

Hospital Ruber Internacional

Madrid, , Spain

Hospital Universitario Ramón y Cajal

Madrid, , Spain

Hospital Clínico San Carlos

Madrid, , Spain

Hospital Clínico Universitario San Carlos

Madrid, , Spain

Hospital Universitario Fundación Jiménez Díaz

Madrid, , Spain

Hospital Universitario 12 de Octubre

Madrid, , Spain

Hospital Universitario La Paz

Madrid, , Spain

Hospital HM Montepríncipe

Madrid, , Spain

Hospital Universitario de Torrejón

Madrid, , Spain

Hospital Universitario Puerta de Hierro Majadahonda

Majadahonda Madrid, , Spain

Hospital Universitario Puerta de Hierro Majadahonda

Majdahonda Madrid, , Spain

Hospital Costa del Sol

Marbella Málaga, , Spain

Consulta de Cardiología Dr. Javier Mora Robles

Málaga, , Spain

Hospital Regional Universitario de Málaga

Málaga, , Spain

Hospital Universitario Virgen de La Victoria

Málaga, , Spain

Hospital de Mendaro

Mendaro, , Spain

Hospital General Universitario Reina Sofía

Murcia, , Spain

Hospital Clínico Universitario Virgen Arrixaca

Murcia, , Spain

Hospital Universitario Son LLatzer

Palma de Mallorca, , Spain

Hospital Universitario de Navarra

Pamplona, , Spain

Hospital de Sagunto

Port de Sagunt, , Spain

Hospital Universitario de Salamanca

Salamanca, , Spain

Hospital Universitario Marqués de Valdecilla

Santander, , Spain

Hospital de Valme

Seville, , Spain

Hospital Universitario Vírgen del Rocío

Seville, , Spain

Hospital General Universitario de Toledo

Toledo, , Spain

Hospital Clínico Universitario de Valencia

Valencia, , Spain

Hospital Arnau de Vilanova

Valencia, , Spain

Vithas Valencia 9 de Octubre

Valencia, , Spain

Consorcio Hospital General Universitario de Valencia

Valencia, , Spain

Hospital Universitari i Politècnic La Fe

Valencia, , Spain

Hospital Universitario Rio Hortega

Valladolid, , Spain

Hospital de La Plana

Villarreal, Castellón, , Spain

Hospital Clinico Universitaro Lozano Blesa

Zaragoza, , Spain

Diabetologie & Endokrinologie Baden

Baden, , Switzerland

University Hospital Basel

Basel, , Switzerland

Inselspital, Universitätsspital Bern

Bern, , Switzerland

Praxis Dr. med Urs Beat Gröflin

Binningen, , Switzerland

Hochgebirgsklinik Davos

Davos, , Switzerland

Spital Lachen AG

Lachen, , Switzerland

Centre Hospitalier Universitaire Vaudois (CHUV)

Lausanne, , Switzerland

University of Lausanne

Lausanne, , Switzerland

Kantonsspital Baselland

Liestal, , Switzerland

EOC Ente Ospedaliero Cantonale

Lugano, , Switzerland

MIP Associazione Medico in Pratica c/o Studio Medico Cardiologico Acquistapace

Lugano, , Switzerland

Praxis Prof. Dr. med. Gottfried Rudofsky

Olten, , Switzerland

HÔPITAL RIVIERA-CHABLAIS, VAUD-VALAIS, Centre hospitalier de Rennaz

Rennaz, , Switzerland

Kantonsspital St.Gallen

Sankt Gallen, , Switzerland

Spital Thun

Thun, , Switzerland

Prof. Dr. med. Stephane Bosquet

Yverdon-les-Bains, , Switzerland

Universitätsspital Zürich

Zurich, , Switzerland

Royal United Hospitals Bath NHS Foundation Trust

Bath, , United Kingdom

South Eastern Ulster Hospital

Belfast, , United Kingdom

University Hospital of Wales

Cardiff, , United Kingdom

Rowden Surgery

Chippenham, , United Kingdom

Craigavon Area Hospital

Craigavon, , United Kingdom

Darlington Memorial Hospital

Darlington, , United Kingdom

University Hospital North Durham

Durham, , United Kingdom

Oaks Healthcare

Hampshire, , United Kingdom

West Morland General Hospital

Kendal, , United Kingdom

North Blaby PCN

Leicester, , United Kingdom

Barts Health NHS Trust/ QMUL

London, , United Kingdom

Freuchen Medical Centre

London, , United Kingdom

Royal Free Hospital Lipid Clinic

London, , United Kingdom

Hammersmith Hospital

London, , United Kingdom

Imperial College London

London, , United Kingdom

Manchester Royal Infirmary

Manchester, , United Kingdom

Manchester University NHS Foundation Trust

Manchester, , United Kingdom

Manchester University NHS Foundation Trust

Manchester, , United Kingdom

Wythenshawe Hospital

Manchester, , United Kingdom

STRIVE, The James Cook University Hospital

Middlesbrough, , United Kingdom

North Tees Hospital

Northumbria, , United Kingdom

City Hospital

Nottingham, , United Kingdom

Queen Alexandra Hospital

Portsmouth, , United Kingdom

Whiston Hospital

Prescot, , United Kingdom

North Manchester General Hospital

Salford, , United Kingdom

Queen's Hospital Lipid Clinic

Staffordshire, , United Kingdom

Princess Royal Hospital

Telford, , United Kingdom

Torbay and South Devon NHS Foundation Trust

Torquay, , United Kingdom

Trowbridge Health Centre

Trowbridge, , United Kingdom

North Wales Cardiac Centre

Wales, , United Kingdom

Wansford and Kings Cliffe Practice

Wansford, , United Kingdom

Bridgewater Surgeries

Watford, , United Kingdom

Countries

Austria; Belgium; Germany; Italy; Netherlands; Spain; Switzerland; United Kingdom

Other Identifiers

DSE-BMP-01-20-EU

Identifier Type: -

Identifier Source: org_study_id