Cryolipolysis Induced Gluteal Fat Change

NCT ID: NCT04568187

Last Updated: 2020-12-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-05-01

Study Completion Date

2010-08-31

Brief Summary

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There was no difference in efficacy in removal of local fat on thigh by cryolipolysis through Zeltiq machine.

Cryolipolysis was found to be safe for 12 week clinical trial.

Detailed Description

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this study is conducted to investigate the clinical efficacy and safety of cryolipolysis on fat removal of thigh through cryolipolysis.

Healthy premenopausal volunteered women had been conducted to assess their anthropometrical, social, and cardio-metabolic, and femoral fat amount by computer tomography, and adverse events at initial, 4 week, 12 week visit.

Conditions

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Body Weight Changes

Keywords

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fat cryolipolysis Women femoral fat

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SEQUENTIAL

the sequential split-body trials
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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cryolipolysis machine on Left inner thigh

Zeltiq machine as intervention procedure was carried out on left inner thigh (treated side) for 1 hour through cool sculpting procedure with CIF (Cooling Intensity Factor: -73 mW/cm2).

Group Type ACTIVE_COMPARATOR

zeltiq

Intervention Type DEVICE

Zeltiq prototype device (Zeltiq Aesthetics, Pleasanton, CA) approved by FDA 2010

radiofrequency on right thigh

The radio frequency method was applied on right thigh (control side) as sham procedure for 30 minutes through 3000 Hz- amplitude modulated frequency at once.

Group Type SHAM_COMPARATOR

placebo

Intervention Type DEVICE

radiofrequency with 3000 Hz

Interventions

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zeltiq

Zeltiq prototype device (Zeltiq Aesthetics, Pleasanton, CA) approved by FDA 2010

Intervention Type DEVICE

placebo

radiofrequency with 3000 Hz

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* pre-menopausal healthy women
* subjects with body mass index ≥ 18
* subjects with visible fat on both thigh
* subjects to understand and agree to this study protocol

Exclusion Criteria

* subjects with cryoglobulinemia, cold urticaria, or paroxysmal cold hemogobulinemia
* subjects with pregnancy or lactation within 6 months or next 3 months
* subjects with any laboratory, or metabolic abnormalities
* uncooperative subjects to comply with the study protocol
* women taking any medication/ over the counter/herbal supplements to regulate weight or fat mass over 6 months
* subjects with menstrual irregularities
* subjects to change over 10% of the former weight within the past 6 months - any procedure such as liposuction, or another surgical procedure or mesotherapy to reduce fat within 6 months
* subjects with any dermatologic abnormalities on the target areas (thigh)
* subjects with any injection into the area of intended treatment (e.g. cortisone) within 6 months
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Wonik Trade Company, Korea

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Kyu R Lee, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Hongik General Hospital

Locations

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Bariatric clinic/Family medicine, Hong-Ik General Hospital

Seoul, , South Korea

Site Status

Countries

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South Korea

Related Links

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http://dx.doi.org/10.4172/2165-7904.1000203

clinical efficacy of fat reduction on the thigh of Korean women through cryolipolysis

Other Identifiers

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01177787

Identifier Type: -

Identifier Source: org_study_id