Trial Outcomes & Findings for LLIN Evaluation in Uganda Project (NCT NCT04566510)
NCT ID: NCT04566510
Last Updated: 2024-11-14
Results Overview
Number of cases of laboratory-confirmed malaria diagnosed at the MRC among patients residing in the catchment areas per unit time/the population of the catchment areas
Recruitment status
COMPLETED
Study phase
NA
Target enrollment
32895 participants
Primary outcome timeframe
24 months following LLIN distribution
Results posted on
2024-11-14
Participant Flow
Households from each of the 64 clusters was randomly selected for participation in each of the community surveys. Within each cluster (MRC target area), households were randomly sampled from a list of households enumerated by the study team, until 50 households with children aged 2-10 years were sampled per cluster.
Only participants in the MRC target areas who participated in cross sectional surveys were considered enrolled while all other persons living in the target areas were not enrolled.
Unit of analysis: MRC target area
Participant milestones
| Measure |
Royal Guard
alpha-cypermethrin + pyriproxyfen (PPF)
long lasting insecticidal nets with alpha-cypermethrin + pyriproxyfen (PPF LLIN, Royal Guard)): Next-generation bed net combining insecticides with different modes of action
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
PermaNet 3.0
deltamethrin + piperonyl butoxide (PBO)
long lasting insecticidal nets with deltamethrin + piperonyl butoxide (PBO LLIN, PermaNet 3.0)): Next-generation bed net combining an insecticide with a synergist
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
|---|---|---|
|
12 Month Cross Sectional Survey
STARTED
|
7940 32
|
8249 32
|
|
12 Month Cross Sectional Survey
COMPLETED
|
7940 32
|
8249 32
|
|
12 Month Cross Sectional Survey
NOT COMPLETED
|
0 0
|
0 0
|
|
24 Month Cross Sectional Period
STARTED
|
8306 32
|
8400 32
|
|
24 Month Cross Sectional Period
COMPLETED
|
8306 32
|
8400 32
|
|
24 Month Cross Sectional Period
NOT COMPLETED
|
0 0
|
0 0
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
LLIN Evaluation in Uganda Project
Baseline characteristics by cohort
| Measure |
Royal Guard
n=92648 Participants
alpha-cypermethrin + pyriproxyfen (PPF)
long lasting insecticidal nets with alpha-cypermethrin + pyriproxyfen (PPF LLIN, Royal Guard)): Next-generation bed net combining insecticides with different modes of action
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
PermaNet 3.0
n=99132 Participants
deltamethrin + piperonyl butoxide (PBO)
long lasting insecticidal nets with deltamethrin + piperonyl butoxide (PBO LLIN, PermaNet 3.0)): Next-generation bed net combining an insecticide with a synergist
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
Total
n=191780 Participants
Total of all reporting groups
|
|---|---|---|---|
|
Age, Continuous
|
19.7 years
STANDARD_DEVIATION 17.6 • n=5 Participants
|
19.9 years
STANDARD_DEVIATION 17.3 • n=7 Participants
|
19.8 years
STANDARD_DEVIATION 17.4 • n=5 Participants
|
|
Sex: Female, Male
Female
|
46324 Participants
n=5 Participants
|
49566 Participants
n=7 Participants
|
95890 Participants
n=5 Participants
|
|
Sex: Female, Male
Male
|
46324 Participants
n=5 Participants
|
49566 Participants
n=7 Participants
|
95890 Participants
n=5 Participants
|
|
Race (NIH/OMB)
American Indian or Alaska Native
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Asian
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Black or African American
|
92648 Participants
n=5 Participants
|
99132 Participants
n=7 Participants
|
191780 Participants
n=5 Participants
|
|
Race (NIH/OMB)
White
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
More than one race
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Incidence of malaria in residence of all ages from MRC target areas
|
15621 episodes of malaria over 3 months
n=5 Participants
|
16763 episodes of malaria over 3 months
n=7 Participants
|
32384 episodes of malaria over 3 months
n=5 Participants
|
PRIMARY outcome
Timeframe: 24 months following LLIN distributionPopulation: estimated number of residents of all ages from MRC target areas; these estimates came from routine surveillance data that did not involve consent or enrollment
Number of cases of laboratory-confirmed malaria diagnosed at the MRC among patients residing in the catchment areas per unit time/the population of the catchment areas
Outcome measures
| Measure |
Royal Guard
n=96360 Participants
alpha-cypermethrin + pyriproxyfen (PPF)
long lasting insecticidal nets with alpha-cypermethrin + pyriproxyfen (PPF LLIN, Royal Guard)): Next-generation bed net combining insecticides with different modes of action
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
PermaNet 3.0
n=103106 Participants
deltamethrin + piperonyl butoxide (PBO)
long lasting insecticidal nets with deltamethrin + piperonyl butoxide (PBO LLIN, PermaNet 3.0)): Next-generation bed net combining an insecticide with a synergist
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
|---|---|---|
|
Malaria Incidence
|
90466 episodes of malaria over 24 months
|
95898 episodes of malaria over 24 months
|
SECONDARY outcome
Timeframe: 12 months following LLIN distributionPopulation: children 2-10 years of age enrolled in cross-sectional surveys
Proportion of children aged 2-10 years at the time of cross-sectional surveys with blood smears positive for parasites by microscopy
Outcome measures
| Measure |
Royal Guard
n=2482 Participants
alpha-cypermethrin + pyriproxyfen (PPF)
long lasting insecticidal nets with alpha-cypermethrin + pyriproxyfen (PPF LLIN, Royal Guard)): Next-generation bed net combining insecticides with different modes of action
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
PermaNet 3.0
n=2411 Participants
deltamethrin + piperonyl butoxide (PBO)
long lasting insecticidal nets with deltamethrin + piperonyl butoxide (PBO LLIN, PermaNet 3.0)): Next-generation bed net combining an insecticide with a synergist
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
|---|---|---|
|
Prevalence of Parasitaemia
|
654 participants with parasitemia
|
521 participants with parasitemia
|
SECONDARY outcome
Timeframe: 24 months following LLIN distributionPopulation: children 2-10 years of age enrolled in cross-sectional surveys
Proportion children aged 2-10 years at the time of cross-sectional surveys with blood smears positive for parasites by microscopy
Outcome measures
| Measure |
Royal Guard
n=2208 Participants
alpha-cypermethrin + pyriproxyfen (PPF)
long lasting insecticidal nets with alpha-cypermethrin + pyriproxyfen (PPF LLIN, Royal Guard)): Next-generation bed net combining insecticides with different modes of action
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
PermaNet 3.0
n=2311 Participants
deltamethrin + piperonyl butoxide (PBO)
long lasting insecticidal nets with deltamethrin + piperonyl butoxide (PBO LLIN, PermaNet 3.0)): Next-generation bed net combining an insecticide with a synergist
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
|---|---|---|
|
Prevalence of Parasitaemia
|
651 participants with parasitemia
|
602 participants with parasitemia
|
SECONDARY outcome
Timeframe: 12 months following LLIN distributionPopulation: children 2-4 years of age enrolled in cross-sectional surveys
Proportion of children aged 2-4 years with haemoglobin \< 11 g/dL at the time of cross-sectional surveys
Outcome measures
| Measure |
Royal Guard
n=1022 Participants
alpha-cypermethrin + pyriproxyfen (PPF)
long lasting insecticidal nets with alpha-cypermethrin + pyriproxyfen (PPF LLIN, Royal Guard)): Next-generation bed net combining insecticides with different modes of action
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
PermaNet 3.0
n=1065 Participants
deltamethrin + piperonyl butoxide (PBO)
long lasting insecticidal nets with deltamethrin + piperonyl butoxide (PBO LLIN, PermaNet 3.0)): Next-generation bed net combining an insecticide with a synergist
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
|---|---|---|
|
Prevalence of Anaemia
|
347 participants with hemoglobin <11g/dL
|
385 participants with hemoglobin <11g/dL
|
SECONDARY outcome
Timeframe: 24 months following LLIN distributionPopulation: children 2-4 years of age enrolled in cross-sectional surveys
Proportion of children aged 2-4 years with haemoglobin \< 11 g/dL at the time of cross-sectional surveys
Outcome measures
| Measure |
Royal Guard
n=937 Participants
alpha-cypermethrin + pyriproxyfen (PPF)
long lasting insecticidal nets with alpha-cypermethrin + pyriproxyfen (PPF LLIN, Royal Guard)): Next-generation bed net combining insecticides with different modes of action
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
PermaNet 3.0
n=971 Participants
deltamethrin + piperonyl butoxide (PBO)
long lasting insecticidal nets with deltamethrin + piperonyl butoxide (PBO LLIN, PermaNet 3.0)): Next-generation bed net combining an insecticide with a synergist
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
|---|---|---|
|
Prevalence of Anaemia
|
178 participants with hemoglobin <11g/dL
|
191 participants with hemoglobin <11g/dL
|
SECONDARY outcome
Timeframe: 12 months following LLIN distributionPopulation: households enrolled in 12 month cross-sectional surveys
Proportion of households with at least one LLIN at the time of cross-sectional surveys
Outcome measures
| Measure |
Royal Guard
n=1747 households
alpha-cypermethrin + pyriproxyfen (PPF)
long lasting insecticidal nets with alpha-cypermethrin + pyriproxyfen (PPF LLIN, Royal Guard)): Next-generation bed net combining insecticides with different modes of action
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
PermaNet 3.0
n=1771 households
deltamethrin + piperonyl butoxide (PBO)
long lasting insecticidal nets with deltamethrin + piperonyl butoxide (PBO LLIN, PermaNet 3.0)): Next-generation bed net combining an insecticide with a synergist
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
|---|---|---|
|
Proportion of Households That Owned at Least One LLIN
|
1571 households with at least 1 LLIN
|
1628 households with at least 1 LLIN
|
SECONDARY outcome
Timeframe: 24 months following LLIN distributionPopulation: households enrolled in 24 month cross-sectional surveys
Proportion of households with at least one LLIN at the time of cross-sectional surveys
Outcome measures
| Measure |
Royal Guard
n=1682 households
alpha-cypermethrin + pyriproxyfen (PPF)
long lasting insecticidal nets with alpha-cypermethrin + pyriproxyfen (PPF LLIN, Royal Guard)): Next-generation bed net combining insecticides with different modes of action
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
PermaNet 3.0
n=1690 households
deltamethrin + piperonyl butoxide (PBO)
long lasting insecticidal nets with deltamethrin + piperonyl butoxide (PBO LLIN, PermaNet 3.0)): Next-generation bed net combining an insecticide with a synergist
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
|---|---|---|
|
Proportion of Households That Owned at Least One LLIN
|
1345 households with at least 1 LLIN
|
1384 households with at least 1 LLIN
|
SECONDARY outcome
Timeframe: 12 months following LLIN distributionPopulation: households enrolled in 12 month cross-sectional surveys
Proportion of households with at least one LLIN per every two occupants at the time of cross-sectional surveys
Outcome measures
| Measure |
Royal Guard
n=1747 households
alpha-cypermethrin + pyriproxyfen (PPF)
long lasting insecticidal nets with alpha-cypermethrin + pyriproxyfen (PPF LLIN, Royal Guard)): Next-generation bed net combining insecticides with different modes of action
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
PermaNet 3.0
n=1771 households
deltamethrin + piperonyl butoxide (PBO)
long lasting insecticidal nets with deltamethrin + piperonyl butoxide (PBO LLIN, PermaNet 3.0)): Next-generation bed net combining an insecticide with a synergist
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
|---|---|---|
|
Proportion of Households That Owned at Least One LLIN for Every Two Occupants
|
987 households with at least 1 LLIN/2persons
|
1060 households with at least 1 LLIN/2persons
|
SECONDARY outcome
Timeframe: 24 months following LLIN distributionPopulation: households enrolled in 24 month cross-sectional surveys
Proportion of households with at least one LLIN per every two occupants at the time of cross-sectional surveys
Outcome measures
| Measure |
Royal Guard
n=1682 households
alpha-cypermethrin + pyriproxyfen (PPF)
long lasting insecticidal nets with alpha-cypermethrin + pyriproxyfen (PPF LLIN, Royal Guard)): Next-generation bed net combining insecticides with different modes of action
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
PermaNet 3.0
n=1690 households
deltamethrin + piperonyl butoxide (PBO)
long lasting insecticidal nets with deltamethrin + piperonyl butoxide (PBO LLIN, PermaNet 3.0)): Next-generation bed net combining an insecticide with a synergist
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
|---|---|---|
|
Proportion of Households That Owned at Least One LLIN for Every Two Occupants
|
650 households with at least 1LLIN/2persons
|
695 households with at least 1LLIN/2persons
|
SECONDARY outcome
Timeframe: 12 months following LLIN distributionPopulation: household residents enrolled in 12 month cross-sectional surveys
Proportion of households residents who report sleeping under LLIN the previous night at the time of cross-sectional surveys
Outcome measures
| Measure |
Royal Guard
n=7940 Participants
alpha-cypermethrin + pyriproxyfen (PPF)
long lasting insecticidal nets with alpha-cypermethrin + pyriproxyfen (PPF LLIN, Royal Guard)): Next-generation bed net combining insecticides with different modes of action
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
PermaNet 3.0
n=8249 Participants
deltamethrin + piperonyl butoxide (PBO)
long lasting insecticidal nets with deltamethrin + piperonyl butoxide (PBO LLIN, PermaNet 3.0)): Next-generation bed net combining an insecticide with a synergist
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
|
|---|---|---|
|
Proportion of Household Residents Who Slept Under an LLIN the Previous Night
|
6045 residents reported sleeping under LLIN
|
6121 residents reported sleeping under LLIN
|
SECONDARY outcome
Timeframe: 24 months following LLIN distributionPopulation: household residents enrolled in 24 month cross-sectional surveys
Proportion of households residents who report sleeping under LLIN the previous night at the time of cross-sectional surveys
Outcome measures
| Measure |
Royal Guard
n=8306 Participants
alpha-cypermethrin + pyriproxyfen (PPF)
long lasting insecticidal nets with alpha-cypermethrin + pyriproxyfen (PPF LLIN, Royal Guard)): Next-generation bed net combining insecticides with different modes of action
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
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PermaNet 3.0
n=8400 Participants
deltamethrin + piperonyl butoxide (PBO)
long lasting insecticidal nets with deltamethrin + piperonyl butoxide (PBO LLIN, PermaNet 3.0)): Next-generation bed net combining an insecticide with a synergist
Social behaviour change communication: SBCC activities will use digital and other platforms, similar to those used for the COVID-19 response, including the following: (1) LLIN launch on television and radio; (2) regional advocacy meetings on Zoom; (3) mass media platforms (for advertisements, mini skits, DJ mentions, radio spots, interactive talks); (4) social media platforms; (5) VHTs; (6) operation hotlines and toll-free call centres; (7) community mobilisation (megaphones); and (8) use of appropriate information, education, and communication materials. Communication will include messages about COVID-19, malaria, and use, care, repair and repurposing of LLINs.
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|---|---|---|
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Proportion of Household Residents Who Slept Under an LLIN the Previous Night
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5117 residents reporting sleeping under LLIN
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5341 residents reporting sleeping under LLIN
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Adverse Events
Royal Guard
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
PermaNet 3.0
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place