Trial Outcomes & Findings for Pilot Study Investigating the Efficacy of Fat Grafting as a Treatment for Male and Female Facial Acne Scarring (NCT NCT04559022)

Last Updated: 2024-10-26

Results Overview

The Goodman and Baron Qualitative Acne Scale will be used to assess acne scars. Grade 1- Macular Disease: Erythematous, hyper- or hypopigmented flat marks Grade 2- Mild Disease: Mild rolling, small soft papular Grade 3- Moderate Disease: More significant rolling, shallow "box car", mild to moderate hypertrophic or papular scars Garde 4- Severe disease: Punched out atrophic, "ice pick", bridges and tunnels, gross atrophy, dystrophic, scars significant hypertrophy or keloid

Recruitment status

COMPLETED

Study phase

Target enrollment

10 participants

Primary outcome timeframe

Baseline

Results posted on

2024-10-26

Participant Flow

Participant milestones

Participant milestones
Measure	Fat Grafting for Acne Scar Treatment This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face. Fat Grafting: This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face.
Overall Study STARTED	10
Overall Study COMPLETED	10
Overall Study NOT COMPLETED	0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Pilot Study Investigating the Efficacy of Fat Grafting as a Treatment for Male and Female Facial Acne Scarring

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	Fat Grafting for Acne Scar Treatment n=10 Participants This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face. Fat Grafting: This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face.
Age, Categorical <=18 years	0 Participants n=5 Participants
Age, Categorical Between 18 and 65 years	10 Participants n=5 Participants
Age, Categorical >=65 years	0 Participants n=5 Participants
Sex: Female, Male Female	7 Participants n=5 Participants
Sex: Female, Male Male	3 Participants n=5 Participants
Ethnicity (NIH/OMB) Hispanic or Latino	2 Participants n=5 Participants
Ethnicity (NIH/OMB) Not Hispanic or Latino	8 Participants n=5 Participants
Ethnicity (NIH/OMB) Unknown or Not Reported	0 Participants n=5 Participants
Race (NIH/OMB) American Indian or Alaska Native	0 Participants n=5 Participants
Race (NIH/OMB) Asian	0 Participants n=5 Participants
Race (NIH/OMB) Native Hawaiian or Other Pacific Islander	0 Participants n=5 Participants
Race (NIH/OMB) Black or African American	0 Participants n=5 Participants
Race (NIH/OMB) White	9 Participants n=5 Participants
Race (NIH/OMB) More than one race	1 Participants n=5 Participants
Race (NIH/OMB) Unknown or Not Reported	0 Participants n=5 Participants
Fitzpatrick Skin Score Type 1	0 Participants n=5 Participants
Fitzpatrick Skin Score Type 2	6 Participants n=5 Participants
Fitzpatrick Skin Score Type 3	1 Participants n=5 Participants
Fitzpatrick Skin Score Type 4	3 Participants n=5 Participants
Fitzpatrick Skin Score Type 5	0 Participants n=5 Participants
Fitzpatrick Skin Score Type 6	0 Participants n=5 Participants

PRIMARY outcome

Timeframe: Baseline

Outcome measures

Outcome measures
Measure	Fat Grafting for Acne Scar Treatment n=10 Participants This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face. Fat Grafting: This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face.	Clinician Assessment The Clinician GAIS was completed after study completion.	Reticular Dermis- Type I Collagen Microbiopsies were collected at baseline and follow up visits. Analysis was used to correlate changes seen with noninvasive skin measurements and clinical assessment with histological changes in ultrastructure.	Reticular Dermis- Type III Collagen Microbiopsies were collected at baseline and follow up visits. Analysis was used to correlate changes seen with noninvasive skin measurements and clinical assessment with histological changes in ultrastructure.	Matrix Metalloproteinase-2 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.	Tissue Growth Factor B1 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.	Tissue Growth Factor B3 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.
Subject Acne Severity Scale Grade 1: Macular	0 Participants	—	—	—	—	—	—
Subject Acne Severity Scale Grade 2: Mild	1 Participants	—	—	—	—	—	—
Subject Acne Severity Scale Grade 3: Moderate	2 Participants	—	—	—	—	—	—
Subject Acne Severity Scale Grade 4: Severe	7 Participants	—	—	—	—	—	—

PRIMARY outcome

Timeframe: Month 3 and Month 6

Subjects and Clinicians will evaluate efficacy of treatment at follow up visits. The photographs from follow up visits will be compared to their baseline photographs. Acne scars on patients will be assessed using the Global Aesthetic Improvement Scale by subject and clinician. CGAIS Rating 1. Very much improved: Optimal cosmetic result. 2. Much improved: Marked improvement in appearance from the initial condition, but not completely optimal. 3. Improved: Obvious improvement in appearance from initial condition. 4. No Change: The appearance is essentially the same as the original condition. 5. Worse: The appearance is worse than the original condition.

Outcome measures

Outcome measures
Measure	Fat Grafting for Acne Scar Treatment n=10 Participants This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face. Fat Grafting: This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face.	Clinician Assessment n=10 Participants The Clinician GAIS was completed after study completion.	Reticular Dermis- Type I Collagen Microbiopsies were collected at baseline and follow up visits. Analysis was used to correlate changes seen with noninvasive skin measurements and clinical assessment with histological changes in ultrastructure.	Reticular Dermis- Type III Collagen Microbiopsies were collected at baseline and follow up visits. Analysis was used to correlate changes seen with noninvasive skin measurements and clinical assessment with histological changes in ultrastructure.	Matrix Metalloproteinase-2 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.	Tissue Growth Factor B1 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.	Tissue Growth Factor B3 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.
Facial Photograph Assessments- Global Aesthetic Improvement Scale Month 3	2.7 units on a scale Standard Error .36	3 units on a scale Standard Error .37	—	—	—	—	—
Facial Photograph Assessments- Global Aesthetic Improvement Scale Month 6	2.8 units on a scale Standard Error .26	3.2 units on a scale Standard Error .25	—	—	—	—	—

PRIMARY outcome

Timeframe: Baseline and 6 Months

MiraVex will be used to assess changes in texture (roughness) of the subjects facial acne scars.

Outcome measures

Outcome measures
Measure	Fat Grafting for Acne Scar Treatment n=10 Participants This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face. Fat Grafting: This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face.	Clinician Assessment n=10 Participants The Clinician GAIS was completed after study completion.	Reticular Dermis- Type I Collagen Microbiopsies were collected at baseline and follow up visits. Analysis was used to correlate changes seen with noninvasive skin measurements and clinical assessment with histological changes in ultrastructure.	Reticular Dermis- Type III Collagen Microbiopsies were collected at baseline and follow up visits. Analysis was used to correlate changes seen with noninvasive skin measurements and clinical assessment with histological changes in ultrastructure.	Matrix Metalloproteinase-2 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.	Tissue Growth Factor B1 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.	Tissue Growth Factor B3 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.
Topographical Analysis of Texture Maximum Depth of Depressions (mm)	0.1495 mm Standard Error 0.019	0.0536 mm Standard Error 0.017	—	—	—	—	—
Topographical Analysis of Texture Roughness (Ra)	17.55 mm Standard Error 1.5	16.58 mm Standard Error 1.6	—	—	—	—	—

PRIMARY outcome

Timeframe: Baseline, 3 Months and 6 Months

Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.

Outcome measures

Outcome measures
Measure	Fat Grafting for Acne Scar Treatment n=10 Participants This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face. Fat Grafting: This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face.	Clinician Assessment n=10 Participants The Clinician GAIS was completed after study completion.	Reticular Dermis- Type I Collagen n=10 Participants Microbiopsies were collected at baseline and follow up visits. Analysis was used to correlate changes seen with noninvasive skin measurements and clinical assessment with histological changes in ultrastructure.	Reticular Dermis- Type III Collagen n=10 Participants Microbiopsies were collected at baseline and follow up visits. Analysis was used to correlate changes seen with noninvasive skin measurements and clinical assessment with histological changes in ultrastructure.	Matrix Metalloproteinase-2 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.	Tissue Growth Factor B1 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.	Tissue Growth Factor B3 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.
Histological Analysis Baseline	1.00 percentage change from baseline Standard Error 0.09	1.00 percentage change from baseline Standard Error .25	1.0 percentage change from baseline Standard Error .18	1.0 percentage change from baseline Standard Error .26	—	—	—
Histological Analysis Month 3	1.07 percentage change from baseline Standard Error 0.13	0.87 percentage change from baseline Standard Error 0.24	0.76 percentage change from baseline Standard Error 0.10	0.74 percentage change from baseline Standard Error 0.08	—	—	—
Histological Analysis Month 6	0.85 percentage change from baseline Standard Error 0.05	0.76 percentage change from baseline Standard Error 0.15	0.85 percentage change from baseline Standard Error 0.06	0.62 percentage change from baseline Standard Error 0.13	—	—	—

PRIMARY outcome

Timeframe: Baseline, 3 Months and 6 Months

Biopsies of the treated are will be taken prior to treatment and post treatment for gene expression analysis. This analysis will identify gene expression related to collagen formation and increased cell turnover.

Outcome measures

Outcome measures
Measure	Fat Grafting for Acne Scar Treatment n=10 Participants This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face. Fat Grafting: This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face.	Clinician Assessment n=10 Participants The Clinician GAIS was completed after study completion.	Reticular Dermis- Type I Collagen n=10 Participants Microbiopsies were collected at baseline and follow up visits. Analysis was used to correlate changes seen with noninvasive skin measurements and clinical assessment with histological changes in ultrastructure.	Reticular Dermis- Type III Collagen n=10 Participants Microbiopsies were collected at baseline and follow up visits. Analysis was used to correlate changes seen with noninvasive skin measurements and clinical assessment with histological changes in ultrastructure.	Matrix Metalloproteinase-2 n=10 Participants Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.	Tissue Growth Factor B1 n=10 Participants Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.	Tissue Growth Factor B3 n=10 Participants Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.
Gene Expression Baseline	1.13 percentage change from baseline Standard Error 0.20	1.21 percentage change from baseline Standard Error 0.34	1.31 percentage change from baseline Standard Error 0.49	1.46 percentage change from baseline Standard Error 0.58	1.17 percentage change from baseline Standard Error 0.24	1.19 percentage change from baseline Standard Error 0.32	1.37 percentage change from baseline Standard Error 0.55
Gene Expression Month 3	1.48 percentage change from baseline Standard Error 0.83	1.68 percentage change from baseline Standard Error 1.00	0.45 percentage change from baseline Standard Error 0.19	0.69 percentage change from baseline Standard Error 0.32	0.66 percentage change from baseline Standard Error 0.28	0.65 percentage change from baseline Standard Error 0.07	0.40 percentage change from baseline Standard Error 0.01
Gene Expression Month 6	0.58 percentage change from baseline Standard Error 0.13	0.58 percentage change from baseline Standard Error 0.12	0.59 percentage change from baseline Standard Error 0.27	0.53 percentage change from baseline Standard Error 0.12	0.43 percentage change from baseline Standard Error 0.12	0.61 percentage change from baseline Standard Error 0.12	0.56 percentage change from baseline Standard Error 0.14

PRIMARY outcome

Timeframe: Baseline and 6 Months

MiraVex will be used to assess changes in depressions of the subjects facial acne scars.

Outcome measures

Outcome measures
Measure	Fat Grafting for Acne Scar Treatment n=10 Participants This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face. Fat Grafting: This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face.	Clinician Assessment n=10 Participants The Clinician GAIS was completed after study completion.	Reticular Dermis- Type I Collagen Microbiopsies were collected at baseline and follow up visits. Analysis was used to correlate changes seen with noninvasive skin measurements and clinical assessment with histological changes in ultrastructure.	Reticular Dermis- Type III Collagen Microbiopsies were collected at baseline and follow up visits. Analysis was used to correlate changes seen with noninvasive skin measurements and clinical assessment with histological changes in ultrastructure.	Matrix Metalloproteinase-2 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.	Tissue Growth Factor B1 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.	Tissue Growth Factor B3 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.
Topographical Analysis of Depressions	11.45 mm^3 Standard Error 2.36	10.64 mm^3 Standard Error 2.4	—	—	—	—	—

SECONDARY outcome

Timeframe: Month 3 and Month 6

Transepidermal Water Loss (TEWL) was measured at baseline and 6 months after treatment.

Outcome measures

Outcome measures
Measure	Fat Grafting for Acne Scar Treatment n=10 Participants This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face. Fat Grafting: This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face.	Clinician Assessment n=10 Participants The Clinician GAIS was completed after study completion.	Reticular Dermis- Type I Collagen Microbiopsies were collected at baseline and follow up visits. Analysis was used to correlate changes seen with noninvasive skin measurements and clinical assessment with histological changes in ultrastructure.	Reticular Dermis- Type III Collagen Microbiopsies were collected at baseline and follow up visits. Analysis was used to correlate changes seen with noninvasive skin measurements and clinical assessment with histological changes in ultrastructure.	Matrix Metalloproteinase-2 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.	Tissue Growth Factor B1 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.	Tissue Growth Factor B3 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.
Noninvasive Skin Assessments- TEWL	8.74 percentage change from baseline Standard Deviation 3.41	35.37 percentage change from baseline Standard Deviation 11.18	—	—	—	—	—

SECONDARY outcome

Timeframe: Month 3 and Month 6

Ultrasonography was used to measure epidermal/dermal thickness/density 3 and 6 months after treatment. Percent change from baseline results are reflected.

Outcome measures

Outcome measures
Measure	Fat Grafting for Acne Scar Treatment n=10 Participants This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face. Fat Grafting: This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face.	Clinician Assessment n=10 Participants The Clinician GAIS was completed after study completion.	Reticular Dermis- Type I Collagen Microbiopsies were collected at baseline and follow up visits. Analysis was used to correlate changes seen with noninvasive skin measurements and clinical assessment with histological changes in ultrastructure.	Reticular Dermis- Type III Collagen Microbiopsies were collected at baseline and follow up visits. Analysis was used to correlate changes seen with noninvasive skin measurements and clinical assessment with histological changes in ultrastructure.	Matrix Metalloproteinase-2 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.	Tissue Growth Factor B1 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.	Tissue Growth Factor B3 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.
Noninvasive Skin Assessments- High-resolution Ultrasonography Epidermal Thickness	-4.28 percentage change from baseline Standard Deviation 12.37	-0.63 percentage change from baseline Standard Deviation 10.98	—	—	—	—	—
Noninvasive Skin Assessments- High-resolution Ultrasonography Epidermal Density	21.34 percentage change from baseline Standard Deviation 22.05	-2.9 percentage change from baseline Standard Deviation 11.96	—	—	—	—	—
Noninvasive Skin Assessments- High-resolution Ultrasonography Dermal Thickness	-26.4 percentage change from baseline Standard Deviation 212.46	-19.4 percentage change from baseline Standard Deviation 330.59	—	—	—	—	—
Noninvasive Skin Assessments- High-resolution Ultrasonography Dermal Density	53.5 percentage change from baseline Standard Deviation 11.248	-12.9 percentage change from baseline Standard Deviation 5.41	—	—	—	—	—

SECONDARY outcome

Timeframe: Month 3 and Month 6

biomechanical analysis of skin deformation was used to measure skin laxity, skin elasticity, viscoelastic deformation, ultimate deformation, stiffness and energy absorption at 3 and 6 months after treatment. Percent change from baseline results are reflected.

Outcome measures

Outcome measures
Measure	Fat Grafting for Acne Scar Treatment n=10 Participants This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face. Fat Grafting: This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face.	Clinician Assessment n=10 Participants The Clinician GAIS was completed after study completion.	Reticular Dermis- Type I Collagen Microbiopsies were collected at baseline and follow up visits. Analysis was used to correlate changes seen with noninvasive skin measurements and clinical assessment with histological changes in ultrastructure.	Reticular Dermis- Type III Collagen Microbiopsies were collected at baseline and follow up visits. Analysis was used to correlate changes seen with noninvasive skin measurements and clinical assessment with histological changes in ultrastructure.	Matrix Metalloproteinase-2 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.	Tissue Growth Factor B1 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.	Tissue Growth Factor B3 Relative changes in protein abundance in biopsies taken at post treatment compare to control or entreated group will be quantified using an image processing software based on fluorescence signal intensity. The change from baseline was calculated at each time frame.
Noninvasive Skin Assessments- Skin Deformation Skin Laxity	-5.88 percentage change from baseline Standard Deviation 0.33	-5.16 percentage change from baseline Standard Deviation 0.36	—	—	—	—	—
Noninvasive Skin Assessments- Skin Deformation Skin Elasticity	7.36 percentage change from baseline Standard Deviation 0.18	-5.62 percentage change from baseline Standard Deviation 0.34	—	—	—	—	—
Noninvasive Skin Assessments- Skin Deformation Viscoelastic Deformation	3.57 percentage change from baseline Standard Deviation 0.03	2.38 percentage change from baseline Standard Deviation 0.34	—	—	—	—	—
Noninvasive Skin Assessments- Skin Deformation Ultimate Deformation	-6.90 percentage change from baseline Standard Deviation 0.25	-11.61 percentage change from baseline Standard Deviation 0.35	—	—	—	—	—
Noninvasive Skin Assessments- Skin Deformation Stiffness	-1.53 percentage change from baseline Standard Deviation 46.22	4.05 percentage change from baseline Standard Deviation 49.68	—	—	—	—	—
Noninvasive Skin Assessments- Skin Deformation Energy Absorption	-2.35 percentage change from baseline Standard Deviation 11.30	-6.07 percentage change from baseline Standard Deviation 0.820	—	—	—	—	—

Adverse Events

Fat Grafting for Acne Scar Treatment

Serious events: 0 serious events

Other events: 1 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Other adverse events
Measure	Fat Grafting for Acne Scar Treatment n=10 participants at risk This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face. Fat Grafting: This single-center, clinical trial will assess the efficacy and tolerability of the autologous fat grafting when used on men and women with acne scars on the face.
General disorders Covid	10.0% 1/10 • Number of events 1 • 18 months

Additional Information

Research Coordinator

UT Southwestern

Phone: 2146458907

Email: [email protected]

Results disclosure agreements

Principal investigator is a sponsor employee
Publication restrictions are in place