Environmental Design for Behavioral Regulation in People With Dementia

NCT ID: NCT04555616

Last Updated: 2023-04-12

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-01-25

Study Completion Date

2021-10-13

Brief Summary

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Individuals with dementia present with changes in behaviors throughout the continuum of cognitive decline. Environmental features may be influential in behavioral regulation. The purpose of this study is to assess the feasibility of environmental design protocols in older adults with dementia and their caregivers. Thirty subjects with moderate to severe Alzheimer's disease as primary dementia type, and their caregivers, will be randomly assigned to one of three arms: standard care; standard environmental design protocol; or personalized environmental design protocol.

Detailed Description

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Conditions

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Alzheimer Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Control Group

Alzheimer's disease patients and caregivers.

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type BEHAVIORAL

Participants' caregivers will receive a set script of placebo modifications.

Standard Environmental Design

Alzheimer's disease patients and caregivers.

Group Type EXPERIMENTAL

Standard Environmental Design

Intervention Type BEHAVIORAL

Participants' caregivers will receive set script of physical environmental modifications (i.e., declutter living space, reduce background noise, increase natural light), and social environment training script will include caregiving techniques: training for calming demeanor (emotional contagion), needs-driven care to decrease behavioral disruption, and accepting and accommodating approach to behavioral disruption. A pre-selected sensory stimulation kit will be provided to each participants' caregiver for administration throughout the day.

Individualized Environmental Design Protocol

Alzheimer's disease patients and caregivers.

Group Type EXPERIMENTAL

Individual Environmental Design

Intervention Type BEHAVIORAL

Participants' caregivers will receive set script of physical environmental modifications and social environment training script in a standard protocol. Following initial assessments, individualized sensory stimulation kits will be developed using subjects' preferred sensory stimuli (as determined by the Adult Sensory Profile assessment and informant report) and will be provided via caregiver administration throughout the day to promote maintained behavioral regulation.

Interventions

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Standard Environmental Design

Participants' caregivers will receive set script of physical environmental modifications (i.e., declutter living space, reduce background noise, increase natural light), and social environment training script will include caregiving techniques: training for calming demeanor (emotional contagion), needs-driven care to decrease behavioral disruption, and accepting and accommodating approach to behavioral disruption. A pre-selected sensory stimulation kit will be provided to each participants' caregiver for administration throughout the day.

Intervention Type BEHAVIORAL

Individual Environmental Design

Participants' caregivers will receive set script of physical environmental modifications and social environment training script in a standard protocol. Following initial assessments, individualized sensory stimulation kits will be developed using subjects' preferred sensory stimuli (as determined by the Adult Sensory Profile assessment and informant report) and will be provided via caregiver administration throughout the day to promote maintained behavioral regulation.

Intervention Type BEHAVIORAL

Placebo

Participants' caregivers will receive a set script of placebo modifications.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Men or women aged 21-90, inclusive.
* Living at home in the community with one primary caregiver.
* Diagnosis of Alzheimer's disease as primary dementia type of moderate to severe stages
* Stable medical condition for one month prior to screening visit
* Stable medications for 4 weeks prior to screening visit
* Caregiver report of challenges related to behaviors within 4 weeks of study enrollment
* Caregiver willing to participant throughout duration of study

Exclusion Criteria

* Unstable medical conditions for 3 months prior to screening
* Wheelchair or bed bound.
* Residence in skilled nursing facility or facility-based care.
* Skin lesions or skin abnormalities throughout upper extremities.
Minimum Eligible Age

21 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Institute on Aging (NIA)

NIH

Sponsor Role collaborator

Elizabeth K Rhodus

OTHER

Sponsor Role lead

Responsible Party

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Elizabeth K Rhodus

Assistant Professor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Gregory Jicha, MD-PhD

Role: STUDY_DIRECTOR

University of Kentucky

Locations

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University of Kentcuky

Lexington, Kentucky, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol, Statistical Analysis Plan, and Informed Consent Form

View Document

Other Identifiers

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T32AG057461

Identifier Type: NIH

Identifier Source: secondary_id

View Link

61291

Identifier Type: -

Identifier Source: org_study_id

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