Sample Collection Study in Patients With Suspected Melanoma Utilizing DermTech's Non-invasive Adhesive Patch Biopsy Kits

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

652 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-03-01

Study Completion Date

2022-07-15

Brief Summary

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A multi-center sample collection study in patients presenting with pigmented lesion(s) suspicious for melanoma. All suspicious lesions should meet at least one of the "ABCDE" criteria.

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Detailed Description

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A multi-center sample collection study in patients presenting with pigmented lesion(s) suspicious for melanoma. All suspicious lesions should meet at least one of the "ABCDE" (asymmetry, border, color, diameter, evolving) criteria. Patients will be consented for the study and screened against the inclusion and exclusion criteria. Once the patient is determined to be acceptable for the study they will be assigned a unique patient number and tissue collection will begin. Tissue from the lesion will be collected using DermTech's non-invasive adhesive patch kit according to the instructions for use followed by surgical biopsy. Digital dermoscopy of the lesion is preferred but not required.

Conditions

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Melanoma (Skin) Pigmented Skin Nevus

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

1. Males and females at least 21 years of age
2. Have a pigmented lesion suspicious for melanoma the pigmented lesion meets at least one of the "ABCDE" criteria
3. The pigmented lesion mst be at least 3mm and not more than 16mm in diameter
4. Patient is willing to follow the start of care to test and treat the pigmented lesion as determined by the treating physician
5. Willing to have DermTech adhesive patch biopsies performed
6. Must be able to complete study procedures as required by the protocol
7. Willing to provide informed consent to participate in this trial

Exclusion Criteria

1. Require a surgical biopsy or excision of the lesion of interest prior to the DermTech non-invasive patch biopsy(ies)
2. Has an ulcerated or bleeding lesion that could confound the biopsy results
3. Has a suspicious lesion(s) in an area that was previously surgically biopsied
4. Has a lesion that is classified as "clinically" evident melanoma appropriate for excision
5. The lesion to be sampled is on the mucosal surface, palmoplantar surface or other area where adhesive patch biopsies cannot be performed
6. Has a known sensitivity to adhesive patches
7. Any significant medical condition that would indicate an unreasonable risk to the patient or potential interference with the study
8. Lesion is in a location were sufficient removal of non-vellus hair cannot be achieved (e.g., scalp)
9. Suspected non-melanoma skin cancer
10. Patients with contraindication(s) to surgical biopsy -

Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No