Lymphocyte - Monocyte Ratio As An Independent Predictor For Progression Of Illness In Patients With Covid-19

NCT ID: NCT04534712

Last Updated: 2023-04-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-09-01

Study Completion Date

2021-10-01

Brief Summary

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Corona virus disease 2019 (COVID 19), first identified in December 2019 in a cluster of population in a Chinese province, soon emerged as a pandemic, causing a huge strain on healthcare system and mortality all over the world. An ideal marker for predicting course of this illness should be easily available and reproducible; as the disease burden has spread to third world countries whose healthcare system is resource limited. Our study is aimed to study the utility of lymphocyte- monocyte ratio in the early stages to predict the progression of COVID 19 pneumonia.

Detailed Description

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Conditions

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Covid19

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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PROGRESSION

Cohort A with patients who progressed to next stage of illness or continue to remain in the same stage

LYMPHOCYTE MONOCYTE RATIO

Intervention Type DIAGNOSTIC_TEST

Absolute lymphicyte and absolute monocyte counts are recorded on admission of COVID -19 positive patient and ratio is derived. the patients are followed up for any progression of disease stage.

NON PROGRESSION

Cohort B with those who improved by two points on the ordinal scale without any further progression

LYMPHOCYTE MONOCYTE RATIO

Intervention Type DIAGNOSTIC_TEST

Absolute lymphicyte and absolute monocyte counts are recorded on admission of COVID -19 positive patient and ratio is derived. the patients are followed up for any progression of disease stage.

Interventions

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LYMPHOCYTE MONOCYTE RATIO

Absolute lymphicyte and absolute monocyte counts are recorded on admission of COVID -19 positive patient and ratio is derived. the patients are followed up for any progression of disease stage.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* All adults of age 18-80 years tested positive for SARS-CoV-2 reverse-transcriptase - polymerase chain reaction (rt-PCR) and presented within 7 days of symptom(s) onset

Exclusion Criteria

* Pregnancy
* Sepsis
* Malignancy
* Patients on immunosuppressant therapy
* Chronic inflammatory conditions
* Cases lost to follow up
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sir Ganga Ram Hospital

OTHER

Sponsor Role collaborator

Post Graduate Institute of Medical Education and Research, Chandigarh

OTHER

Sponsor Role lead

Responsible Party

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VAMSIDHAR

DNB Trainee

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Sir Ganga Ram Hospital

New Delhi, National Capital Territory of Delhi, India

Site Status

Countries

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India

Other Identifiers

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yet to be assigned

Identifier Type: -

Identifier Source: org_study_id

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