Behavioral Weight Loss Program for Cancer Survivors in Maryland

NCT ID: NCT04534309

Last Updated: 2023-10-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

340 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-09-22

Study Completion Date

2023-06-30

Brief Summary

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Behavioral Weight Loss for Overweight and Obese Cancer Survivors in Maryland: A Demonstration Project

Detailed Description

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The objective of the ASPIRE Project is to design, implement, and evaluate a real-world, lifestyle-based, support for overweight or obese cancer survivors in both urban and rural areas of Maryland. The project will provide three options of support to encourage lifestyle change to achieve and maintain a healthy weight for cancer survivors:

1. Self-Directed Weight Loss: educational materials only;
2. App-Directed Weight Loss: educational materials, weight loss app with weekly e-mail support; and
3. Coach-Directed Weight Loss: educational materials, weight loss app, weekly e-mail support and one-to-one weekly telephonic coach support.

Conditions

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Breast Cancer Prostate Cancer Melanoma (Skin) Endometrial Cancer Gallbladder Cancer Rectal Cancer Kidney Cancer Bladder Cancer

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Self-Directed Weight Loss with year-long weight tracking

Written Weight Loss Material.

Group Type OTHER

Written Weight Loss Material

Intervention Type BEHAVIORAL

Participants will receive written weight loss material by email.

App-Directed Weight Loss with year-long weight tracking

Smart phone Weight Loss App.

Group Type OTHER

Weight Loss App

Intervention Type BEHAVIORAL

Participants will receive written weight loss material as well as instructions for using a free weight loss app on their phone or computer.

Coach-Directed Weight Loss with year-long weight tracking

Behavioral Lifestyle Weight Loss Intervention with Smart phone Weight Loss App.

Group Type OTHER

Weight Loss App

Intervention Type BEHAVIORAL

Participants will receive written weight loss material as well as instructions for using a free weight loss app on their phone or computer.

Behavioral Lifestyle Weight Loss Intervention (Coaching)

Intervention Type BEHAVIORAL

Participants will receive weekly coaching phone calls to encourage regular dietary, exercise, and self-monitoring practices which encourage gradual, healthy weight loss.

Interventions

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Written Weight Loss Material

Participants will receive written weight loss material by email.

Intervention Type BEHAVIORAL

Weight Loss App

Participants will receive written weight loss material as well as instructions for using a free weight loss app on their phone or computer.

Intervention Type BEHAVIORAL

Behavioral Lifestyle Weight Loss Intervention (Coaching)

Participants will receive weekly coaching phone calls to encourage regular dietary, exercise, and self-monitoring practices which encourage gradual, healthy weight loss.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* previously diagnosed with a malignant solid tumor,
* completed all required surgical, and/or chemotherapy and/or radiation curative intent therapy at least three months prior to enrollment,
* anticipated treatment-free life span of 12 months or longer.
* chemoprophylaxis with tamoxifen or aromatase inhibitors for breast cancer in women will be permitted
* anti- Luteinizing-hormone releasing therapy for prostate cancer in men will be permitted.
* BMI ≥ 25 kg/m2 (BMI ≥ 23 kg/m2 for Asians) and weight ≤ 400 lbs.
* have an email address for regular personal use

Additional criteria for participants in weight tracking (self-directed or app directed)

* willingness to record/transmit quarterly weights for 12 months

Additional criteria for App-Directed Program:

* willingness to change diet and increase physical activity and track weight, diet and physical activity
* have a smart phone for personal use
* sufficient data plan/Internet to support daily use of weight loss app\*

Additional Criteria for Coach-Directed Weight Loss Program

* willingness to lose weight by changing diet and physical activity habits
* willingness to track weight, diet and physical activity
* willingness to record/transmit quarterly weights for 12 months
* smart phone for personal use
* data plan/Internet to support daily use of weight loss app\*
* willingness to complete coaching calls (12 weekly calls and 3 monthly calls)
* sufficient call plan to support coaching calls

* a corresponding website could be used, then daily Internet access is required for person use.

Exclusion Criteria

* received any chemotherapy (unless anti-hormonal therapy) and/or radiation three months or less prior to the proposed program date
* women who are breastfeeding, pregnant, or planning pregnancy within the next year


* self-identification of uncontrolled concurrent medical condition likely to limit compliance with the program as determined by investigators.
* current involvement in another organized weight loss program
* current use of steroids or other medication known to affect body weight
* bariatric surgery scheduled within the next 6 months, or
* plan to move outside the continental US in the next 12 months
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Maryland Cigarette Restitution Fund

OTHER_GOV

Sponsor Role collaborator

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jessica Yeh, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Johns Hopkins University

Locations

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Johns Hopkins ProHealth

Baltimore, Maryland, United States

Site Status

Countries

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United States

References

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Jerome GJ, Appel LJ, Bunyard L, Dalcin AT, Durkin N, Charleston JB, Kanarek NF, Carducci MA, Wang NY, Yeh HC. Behavioral Weight Loss Programs for Cancer Survivors Throughout Maryland: Protocol for a Pragmatic Trial and Participant Characteristics. JMIR Res Protoc. 2024 Jun 12;13:e54126. doi: 10.2196/54126.

Reference Type DERIVED
PMID: 38865181 (View on PubMed)

Other Identifiers

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IRB00229163

Identifier Type: -

Identifier Source: org_study_id

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