Short Term Outcome of Laparoscopic Trans-abdominal Preperitoneal Inguinal Hernia Repair Without Mesh Fixation

NCT ID: NCT04532983

Last Updated: 2020-08-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

46 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-07-01

Study Completion Date

2020-06-30

Brief Summary

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comparison between two groups of participants suffering inguinal hernia each group 23 individual all underwent laparoscopic trans-abdominal inguinal hernia repair first group received mesh fixation the second underwent no fixation , results of follow up in the first year were compared together

Detailed Description

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This comparative study was performed in Zagazig university hospitals, general surgery department in the time period between july 2018 and june 2020 0n 46 patients undergoing laparoscopic trans abdominal preperitoneal (TAPP) repair for un complicated unilateral inguinal hernia.

Patient selection; In this study we enrolled patients above

* 18 years old suffering unilateral,
* non -recurrent,
* un-complicated inguinal hernia. We excluded patients with
* previous abdominal or pelvic surgery,
* unfit with laparoscopic surgery,
* those with ascites,
* abdominal malignancy
* on chemotherapy and immune-compromised patients.

Randomization; using computer generated random numbers , the study participants were randomly allocated into two equal groups each group 23 individual, the first group; group A; patients underwent laparoscopic TAPP repair of inguinal hernia and the mesh prosthesis was fixed in position using absorbable Vicryl tacks (abstack30 medtronic), and group B patient underwent laparoscopic TAPP repair of inguinal hernia and the mesh prosthesis was placed in position without fixation.

All the study participants were subjected to thorough history taking, detailed clinical examination, determination of the presence of inguinal hernia, measurement of the hernia defect diameter by ultrasound or computerized tomography in difficult cases, preoperative laboratory tests were performed as per usual

Follow up Early postoperative data during the admission were collected, a; pain score (measured by visual analogue scale (VAS), hematoma formation, early recurrence, time needed for ambulation.

Follow up was carried out in outpatients clinics by the attending surgeon after 1 week, 1 month,3 months and 6 months of the operation , the recorded follow up data included wound complications, seroma formation, foreign body sensation and recurrence.

The study was approved by the local ethical committee and institutional review board (IRB) of our university hospitals, all patients signed an informed written consent before participation in this study Preoperative, demographic, operative and postoperative data were collected and properly analyzed using t test, Z test in SPSS 22 program package

Conditions

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Inguinal Hernia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

; group A; patients underwent laparoscopic TAPP repair of inguinal hernia and the mesh prosthesis was fixed in position using absorbable Vicryl tacks (abstack30 medtronic), and group B patient underwent laparoscopic TAPP repair of inguinal hernia and the mesh prosthesis was placed in position without fixation.
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Caregivers
the participants and the follow up surgeon don't know which received fixation

Study Groups

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fixation group

; group A; patients underwent laparoscopic TAPP repair of inguinal hernia and the mesh prosthesis was fixed in position using absorbable Vicryl tacks (abstack30 medtronic),

Group Type ACTIVE_COMPARATOR

fixation of mesh prosthesis

Intervention Type PROCEDURE

in the first group mesh was fixed in position with laparoscopic tacks

non fixation group

group B patient underwent laparoscopic TAPP repair of inguinal hernia and the mesh prosthesis was placed in position without fixation.

Group Type ACTIVE_COMPARATOR

mesh placement without fixation

Intervention Type PROCEDURE

mesh placement in preperitoneal space without fixation

Interventions

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fixation of mesh prosthesis

in the first group mesh was fixed in position with laparoscopic tacks

Intervention Type PROCEDURE

mesh placement without fixation

mesh placement in preperitoneal space without fixation

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* 18 years old suffering unilateral,
* non -recurrent,
* un-complicated inguinal hernia.

Exclusion Criteria

* previous abdominal or pelvic surgery,
* unfit with laparoscopic surgery,
* those with ascites,
* abdominal malignancy
* on chemotherapy and immune-compromised patients.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Zagazig University

OTHER_GOV

Sponsor Role lead

Responsible Party

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Hazem Nour Abdellatif

Assistant professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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hazem nour

Role: PRINCIPAL_INVESTIGATOR

zag university

Locations

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Zagazig Faculty of Medicine

Zagazig, Sharqya, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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hazem tapp no fix

Identifier Type: -

Identifier Source: org_study_id