Impact of Anesthetic Environment the Sex Ratio of the Children of Female Assistants

NCT ID: NCT04532502

Last Updated: 2021-12-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

143 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-10-02

Study Completion Date

2021-12-02

Brief Summary

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The aims of this multi center retrospective study was to determine:

* whether the sex ratio of the offspring of female assistants in anesthesia-resuscitation differs from that of the population at large
* whether the assistants' work environment at the time of their offspring's conception influences the sex of their offspring

Detailed Description

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Conditions

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Anesthesia, General Anesthetics Adverse Reaction

Keywords

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Anesthesia care providers offspring sex ratio Inhalation induction of anesthesia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Study group

All female assistants in anesthesia

Anesthetics, Inhalation

Intervention Type DRUG

Work environmental exposure

Interventions

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Anesthetics, Inhalation

Work environmental exposure

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Female assistants in anesthesia-resuscitation in the Wallonia-Brussels Federation (Belgium) who conceived one or more children in the course of their training between 2009 and 2019 and who delivered before the end of 2019 (cut-off: midnight on 31 December 2019)

Exclusion Criteria

* Male assistants in anesthesia-resuscitation
* Female assistants in anesthesia-resuscitation who trained before 2009 or after 2019.
* Female assistants in anesthesia-resuscitation who relied on medically assisted reproduction.
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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University of Liege

OTHER

Sponsor Role lead

Responsible Party

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Jean François Brichant

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Philippe J Van der Linden, MD

Role: STUDY_DIRECTOR

CHU Brugmann, Free University of Brussels, Belgium

Locations

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ULiege

Liège, , Belgium

Site Status

Countries

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Belgium

References

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Gupta D, Kaminski E, McKelvey G, Wang H. Firstborn offspring sex ratio is skewed towards female offspring in anesthesia care providers: A questionnaire-based nationwide study from United States. J Anaesthesiol Clin Pharmacol. 2013 Apr;29(2):221-7. doi: 10.4103/0970-9185.111728.

Reference Type BACKGROUND
PMID: 23878446 (View on PubMed)

Leroy C, Daelemans C, Debauche C, Van Leeuw V. Santé périnatale en Wallonie - année 2017, Centre d'Epidémiologie Périnatale 2019.

Reference Type BACKGROUND

Other Identifiers

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GENREANES

Identifier Type: -

Identifier Source: org_study_id