Apnoea-Hypopnoea-Indices Determined Via Continuous Positive Airway Pressure vs Those Determined by Polysomnography

NCT ID: NCT04526366

Last Updated: 2021-10-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-03-31

Study Completion Date

2021-05-31

Brief Summary

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To date, no published systematic review and meta-analysis has compared AHI-CPAPflow and AHI-PSGgold. Therefore, the primary objective of this study is to compare published data for AHI-PSGgold and AHI-CPAPflow in patients treated by CPAP.

Detailed Description

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The secondary objectives are to evaluate, in a manner similar to the primary objective, data for apnoea indices (AI), hypopnoea indices (HI), respiratory disturbance indices (RDI) and respiratory effort related arousals (RERAs) and to perform subgroup analyses focusing on the inclusion/exclusion of central apnoea patients, BMI levels, CPAP device brands, pressure titration modes, use of a predetermined and fixed pressure level or not, and the impact of a 4%-PSG desaturation criteria versus 3%-PSG on index accuracy.

Conditions

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Sleep Apnea Syndromes

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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The study population

All (full scientific) study designs and publication types written in English and reporting Bland-Altman test results (or other tests suggesting the presence of the required data) between simultaneous, paired, polysomnography (PSG)-derived AND Continuous Positive Airway Pressure (CPAP)-derived data describing sleep disordered breathing.

Continuous Positive Airway Pressure

Intervention Type DEVICE

Continuous Positive Airway Pressure device deployed for at least one night synchronously with polysomnography.

Polysomnography

Intervention Type DEVICE

Polysomnography deployed for at least one night synchronously with Continuous Positive Airway Pressure.

Interventions

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Continuous Positive Airway Pressure

Continuous Positive Airway Pressure device deployed for at least one night synchronously with polysomnography.

Intervention Type DEVICE

Polysomnography

Polysomnography deployed for at least one night synchronously with Continuous Positive Airway Pressure.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* All (full scientific) study designs and publication types written in English and reporting Bland-Altman test results (or other tests suggesting the presence of the required data) between simultaneous, paired, polysomnography (PSG)-derived AND Continuous Positive Airway Pressure (CPAP)-derived data describing sleep disordered breathing.

Exclusion Criteria

* Duplicates
* Does not refer to a full scientific article (e.g. case reports are excluded).
* Meta-analysis
* Paediatric populations (populations \<18 years are excluded).
* Absence of appropriate paired results: synchronized polysomnography (PSG)-derived AND Continuous Positive Airway Pressure (CPAP)-derived data must be reported for ≥1 of the following measures: Apnoea-Hypopnoea-Indices (AHI), Apnoea-Indices (AI), Hypopnoea-Indices(HI), respiratory disturbance index (RDI), respiratory effort related arousals (RERA).
* Absence of appropriate test comparing paired results: the study must use ≥1 of the fol-lowing tests to compare the previously mentioned PSG-vs-CPAP-derived data: a bland-altman or correlation test, other conformity tests, tests of differences in centrality.
* Inappropriate PSG scoring 1: PSG-derived variables must be coded following the American Academy of Sleep Medicine 2007 (or more recent) guidelines.
* Inappropriate PSG scoring 2: PSG-derived variables must be scored manually.
* Inappropriate PSG scoring 3: oxygen desaturation level used for scoring must be mentioned and at 3% or 4%.
* Inappropriate CPAP description: brand/device names must be mentioned.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Montpellier

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Dany Jaffuel, MD,PhD

Role: STUDY_DIRECTOR

University Hospitals of Montpellier

Locations

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University Hospitals of Montpellier

Montpellier, , France

Site Status

Countries

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France

References

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Bertelli F, Suehs CM, Mallet JP, Rotty MC, Pepin JL, Gagnadoux F, Matzner-Lober E, Bourdin A, Molinari N, Jaffuel D. Apnoea-hypopnoea indices determined via continuous positive airway pressure (AHI-CPAPflow) versus those determined by polysomnography (AHI-PSGgold): a protocol for a systematic review and meta-analysis. BMJ Open. 2021 May 10;11(5):e044499. doi: 10.1136/bmjopen-2020-044499.

Reference Type BACKGROUND
PMID: 33972338 (View on PubMed)

Related Links

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https://osf.io/gycw2/

Meta IAHflow on the Open Science Framework.

Other Identifiers

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RECHMPL20_0395

Identifier Type: -

Identifier Source: org_study_id