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Cardiac Dysfunction in Critically Ill Patients With COVID-19

NCT ID: NCT04524234

Last Updated: 2020-12-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

132 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-04-20

Study Completion Date

2020-09-30

Brief Summary

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Cardiac dysfunction has been reported to be common in patients infected with COVID-19. The aim of this study is to evaluate the clinical importance of cardiac dysfunction in critically ill patients infected with COVID-19.

Detailed Description

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Cardiac dysfunction has been reported to be common in patients infected with COVID-19. The aim of this study is to evaluate the clinical importance of cardiac dysfunction in critically ill patients with COVID-19. Patients admitted to the intensive care unit, with COVID-19 are examined with echocardiography for assessment of left and right ventricular dysfunction within 72 hours from admission and repeated after four to seven days.

Cardiac dysfunction was defined as having either left ventricular (LV) dysfunction, defined as having an ejection fraction \<50% and/or regional hypokinesia, or right ventricular (RV) dysfunction, defined as having a tricuspid annular plane excursion (TAPSE) \<17mm or a moderate/severe RV dysfunction assessed visually.

The cardiac biomarkers troponin and NTproBNP and clinical data are recorded at time of each echo. Mortality status is recorded at 30 days.

Conditions

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Covid19 Left Ventricular Dysfunction Right Ventricular Dysfunction Pulmonary Hypertension

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Echocardiography

Echocardiography for assessment of cardiac function

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sahlgrenska University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Jonatan Oras

Associate professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jonatan Oras, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Sahlgrenska University Hospital

Locations

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Södersjukhuset

Stockholm, Region Stockholm, Sweden

Site Status

Sahlgrenska University Hospital/Mölndal

Gothenburg, Västra Götaland County, Sweden

Site Status

Sahlgrenska University Hospital/Östra

Gothenburg, Västra Götaland County, Sweden

Site Status

Sahlgrenska University Hospital

Gothenburg, Västra Götaland County, Sweden

Site Status

North Älvsborg County Hospital

Trollhättan, Västra Götalandsregionen, Sweden

Site Status

Countries

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Sweden

Other Identifiers

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CARDY CRIT COVID

Identifier Type: -

Identifier Source: org_study_id