Success in Comaneci-assist Coils Embolization Surveillance Study (SUCCESS)

NCT ID: NCT04518670

Last Updated: 2026-01-21

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

90 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-11-24

Study Completion Date

2024-07-07

Brief Summary

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The Comaneci Embolization Assist Device is indicated for use in the neurovasculature as a temporary endovascular device used to assist in the coil embolization of wide-necked intracranial aneurysms with a neck width ≤ 10 mm. A wide-necked intracranial aneurysm (IA) defines the neck width as ≥ 4 mm or a dome-to-neck ratio \< 2.

The objective of the Postmarket Surveillance Plan is to assess safety and performance as used in postmarket clinical practice in the U.S.

Detailed Description

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Conditions

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Intracranial Aneurysm

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Interventions

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Comaneci Embolization Assist Device

assist in the coil embolization of wide-necked intracranial aneurysms with a neck width ≤ 10 mm.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Patient has a documented intracranial ruptured or unruptured aneurysm, suitable for embolization by coils.
2. Patient is considered for treatment with coil embolization assisted by the Comaneci Device for wide-necked intracranial aneurysms with neck width ≤ 10 mm. A wide-necked intracranial aneurysm is defined by the neck width as ≥ 4 mm or a dome-to-neck ratio \< 2.
3. A signed informed consent by the patient or legally authorized representative

Exclusion Criteria

1\. Patient with known hypersensitivity to nickel-titanium
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Rapid Medical

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Hanel Ricardo, Dr.

Role: PRINCIPAL_INVESTIGATOR

Baptist Neurological Institute

Locations

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USA Health University Hospital

Mobile, Alabama, United States

Site Status

Carondelet St. Joseph's Hospital (Tenet)

Tucson, Arizona, United States

Site Status

Santa Barbara Cottage

Santa Barbara, California, United States

Site Status

Los Robles

Thousand Oaks, California, United States

Site Status

Baptist Health Research Institute

Jacksonville, Florida, United States

Site Status

St. Mary's Medical Ctr (Tenet)

West Palm Beach, Florida, United States

Site Status

University of Buffalo

Buffalo, New York, United States

Site Status

Texas Stroke Institute (Sarah Cannon TN)

Dallas, Texas, United States

Site Status

Countries

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United States

References

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Davies JM, Taqi MA, Coon AL, Lin LM, Bohnstedt B, Mascitelli J, Levy EI, Siddiqui A, Birnbaum L, Rodriguez P, Noufal M, Taussky P, Kilburg C, Gooch MR, Puri AS, Diaz O, Fifi JT, Majidi S, Yoo AJ, Soomro J, Bhuva P, Taylor RA, Oni-Orisan AO, Chen M, Sauvageau E, Cordina SM, Sugg RM, Singh J, Goren O, Liebeskind DS, Hanel RA. Comaneci-assisted embolization of wide-necked aneurysms: results from the SUCCESS postmarket US study. J Neurointerv Surg. 2025 Nov 19:jnis-2025-024136. doi: 10.1136/jnis-2025-024136. Online ahead of print.

Reference Type DERIVED
PMID: 41260918 (View on PubMed)

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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CLN-Co-001

Identifier Type: -

Identifier Source: org_study_id

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