Eosinophil and Anticoagulation in COVID-19 Patients

NCT ID: NCT04507282

Last Updated: 2020-08-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-05-15

Study Completion Date

2020-07-15

Brief Summary

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Despite prophylactic anticoagulant treatments, thrombotic complications may develop in patients with Coronavirus disease 2019 (COVID-19). This study aimed to evaluate anti-Factor Xa levels to determine the anticoagulant activity of low molecular weight heparin (LMWH) in COVID-19 patients.

Detailed Description

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Conditions

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COVID-19

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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COVID 19 positive patients

LMWH

Intervention Type DRUG

COVID 19 positive patients anticogulation level, subprophylactic level and prophylactic level

Interventions

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LMWH

COVID 19 positive patients anticogulation level, subprophylactic level and prophylactic level

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients older than 18 years, who were diagnosed with COVID-19 and were administered LMWH,
* agreed to participate in the study were included

Exclusion Criteria

* Patients with previous coagulopathy,
* continuous indication of anticoagulant therapy (atrial fibrillation (AF), valve disease),
* glomerular filtration rate (GFR) \<30 mL/min or undergoing dialysis, or with known liver dysfunction were excluded from the study.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Bursa Postgraduate Hospital

OTHER

Sponsor Role lead

Responsible Party

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Hasan ARI

Medical Doctor of Cardiology

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Bursa Yüksek İhtisas Hastanesi

Yıldırım, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Ari S, Can V, Demir OF, Ari H, Agca FV, Melek M, Camci S, Dikis OS, Huysal K, Turk T. Elevated eosinophil count is related with lower anti-factor Xa activity in COVID-19 patients. J Hematop. 2020 Oct 8;13(4):249-258. doi: 10.1007/s12308-020-00419-3. eCollection 2020 Dec.

Reference Type DERIVED
PMID: 33046998 (View on PubMed)

Other Identifiers

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Bursa Postgraduate Hospital

Identifier Type: -

Identifier Source: org_study_id

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