Trial Outcomes & Findings for COVID-19 Project ECHO in Nursing Homes (NCT NCT04499391)
NCT ID: NCT04499391
Last Updated: 2024-08-22
Results Overview
Rate of COVID-19 infection in enrolled nursing homes, as measured by the cumulative 4-week incidence at study points for Confirmed COVID-19 cases per 1,000 residents
Recruitment status
COMPLETED
Study phase
NA
Target enrollment
136 participants
Primary outcome timeframe
Baseline, 4, 6, 12, 18 months
Results posted on
2024-08-22
Participant Flow
Unit of analysis: Nursing homes
Participant milestones
| Measure |
ECHO Plus
Nursing homes in this arm will receive the intervention via real-time, interactive videoconferencing using Zoom at no cost to participants. Sessions will be 90 minutes in duration and held weekly for 6 months (25 sessions total) at regularly scheduled times. Participants in this arm will receive a 2 month (8 sessions total) refresher course in Fall 2021. Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation
Project ECHO: Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation. This differentiates ECHO from traditional learning and facilitates rapid dissemination of medical knowledge and increased capacity to deliver best-practice care.studying innovative approaches.
|
ECHO
Nursing homes in this arm will receive the intervention via real-time, interactive videoconferencing using Zoom at no cost to participants. Sessions will be 90 minutes in duration and held weekly for 6 months (25 sessions total) at regularly scheduled times. Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation
Project ECHO: Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation. This differentiates ECHO from traditional learning and facilitates rapid dissemination of medical knowledge and increased capacity to deliver best-practice care.studying innovative approaches.
|
|---|---|---|
|
Overall Study
STARTED
|
0 68
|
0 68
|
|
Overall Study
COMPLETED
|
0 64
|
0 62
|
|
Overall Study
NOT COMPLETED
|
0 4
|
0 6
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
Participant age data was not collected.
Baseline characteristics by cohort
| Measure |
ECHO Plus
n=64 Nursing home
Nursing homes in this arm will receive the intervention via real-time, interactive videoconferencing using Zoom at no cost to participants. Sessions will be 90 minutes in duration and held weekly for 6 months (25 sessions total) at regularly scheduled times. Participants in this arm will receive a 2 month (8 sessions total) refresher course in Fall 2021. Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation
Project ECHO: Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation. This differentiates ECHO from traditional learning and facilitates rapid dissemination of medical knowledge and increased capacity to deliver best-practice care.studying innovative approaches.
|
ECHO
n=62 Nursing home
Nursing homes in this arm will receive the intervention via real-time, interactive videoconferencing using Zoom at no cost to participants. Sessions will be 90 minutes in duration and held weekly for 6 months (25 sessions total) at regularly scheduled times. Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation
Project ECHO: Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation. This differentiates ECHO from traditional learning and facilitates rapid dissemination of medical knowledge and increased capacity to deliver best-practice care.studying innovative approaches.
|
Total
n=126 Nursing home
Total of all reporting groups
|
|---|---|---|---|
|
Age, Categorical
<=18 years
|
NA Nursing home
n=64 Nursing home • Participant age data was not collected.
|
NA Nursing home
n=62 Nursing home • Participant age data was not collected.
|
NA Nursing home
n=126 Nursing home • Participant age data was not collected.
|
|
Age, Categorical
Between 18 and 65 years
|
NA Nursing home
n=64 Nursing home • Participant age data was not collected.
|
NA Nursing home
n=62 Nursing home • Participant age data was not collected.
|
NA Nursing home
n=126 Nursing home • Participant age data was not collected.
|
|
Age, Categorical
>=65 years
|
NA Nursing home
n=64 Nursing home • Participant age data was not collected.
|
NA Nursing home
n=62 Nursing home • Participant age data was not collected.
|
NA Nursing home
n=126 Nursing home • Participant age data was not collected.
|
|
Sex: Female, Male
Female
|
NA Nursing home
n=64 Nursing home • Participant gender was not collected.
|
NA Nursing home
n=62 Nursing home • Participant gender was not collected.
|
NA Nursing home
n=126 Nursing home • Participant gender was not collected.
|
|
Sex: Female, Male
Male
|
NA Nursing home
n=64 Nursing home • Participant gender was not collected.
|
NA Nursing home
n=62 Nursing home • Participant gender was not collected.
|
NA Nursing home
n=126 Nursing home • Participant gender was not collected.
|
|
Race (NIH/OMB)
American Indian or Alaska Native
|
NA Nursing home
n=64 Nursing home
|
NA Nursing home
n=62 Nursing home
|
NA Nursing home
n=126 Nursing home
|
|
Race (NIH/OMB)
Asian
|
NA Nursing home
n=64 Nursing home
|
NA Nursing home
n=62 Nursing home
|
NA Nursing home
n=126 Nursing home
|
|
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
|
NA Nursing home
n=64 Nursing home
|
NA Nursing home
n=62 Nursing home
|
NA Nursing home
n=126 Nursing home
|
|
Race (NIH/OMB)
Black or African American
|
NA Nursing home
n=64 Nursing home
|
NA Nursing home
n=62 Nursing home
|
NA Nursing home
n=126 Nursing home
|
|
Race (NIH/OMB)
White
|
NA Nursing home
n=64 Nursing home
|
NA Nursing home
n=62 Nursing home
|
NA Nursing home
n=126 Nursing home
|
|
Race (NIH/OMB)
More than one race
|
NA Nursing home
n=64 Nursing home
|
NA Nursing home
n=62 Nursing home
|
NA Nursing home
n=126 Nursing home
|
|
Race (NIH/OMB)
Unknown or Not Reported
|
NA Nursing home
n=64 Nursing home
|
NA Nursing home
n=62 Nursing home
|
NA Nursing home
n=126 Nursing home
|
|
Location
Rural
|
26 Nursing home
n=64 Nursing home
|
27 Nursing home
n=62 Nursing home
|
53 Nursing home
n=126 Nursing home
|
|
Location
Urban
|
38 Nursing home
n=64 Nursing home
|
35 Nursing home
n=62 Nursing home
|
73 Nursing home
n=126 Nursing home
|
|
Facility Size
<60 Beds
|
17 Nursing home
n=64 Nursing home
|
19 Nursing home
n=62 Nursing home
|
36 Nursing home
n=126 Nursing home
|
|
Facility Size
>=60 beds
|
47 Nursing home
n=64 Nursing home
|
43 Nursing home
n=62 Nursing home
|
90 Nursing home
n=126 Nursing home
|
|
Facility Payment Model
For-profit
|
41 Nursing home
n=64 Nursing home
|
33 Nursing home
n=62 Nursing home
|
74 Nursing home
n=126 Nursing home
|
|
Facility Payment Model
Not-for-profit
|
23 Nursing home
n=64 Nursing home
|
29 Nursing home
n=62 Nursing home
|
52 Nursing home
n=126 Nursing home
|
|
Facility Type
Independent
|
27 Nursing home
n=64 Nursing home
|
32 Nursing home
n=62 Nursing home
|
59 Nursing home
n=126 Nursing home
|
|
Facility Type
Networked
|
37 Nursing home
n=64 Nursing home
|
30 Nursing home
n=62 Nursing home
|
67 Nursing home
n=126 Nursing home
|
|
Memory Care Status
Yes
|
17 Nursing home
n=64 Nursing home
|
10 Nursing home
n=62 Nursing home
|
27 Nursing home
n=126 Nursing home
|
|
Memory Care Status
No
|
47 Nursing home
n=64 Nursing home
|
52 Nursing home
n=62 Nursing home
|
99 Nursing home
n=126 Nursing home
|
|
Baseline Infection Rate
Some
|
53 Nursing home
n=64 Nursing home
|
55 Nursing home
n=62 Nursing home
|
108 Nursing home
n=126 Nursing home
|
|
Baseline Infection Rate
None
|
11 Nursing home
n=64 Nursing home
|
7 Nursing home
n=62 Nursing home
|
18 Nursing home
n=126 Nursing home
|
PRIMARY outcome
Timeframe: Baseline, 4, 6, 12, 18 monthsPopulation: Nursing homes were assigned to Arms/Groups, participant level data is not available
Rate of COVID-19 infection in enrolled nursing homes, as measured by the cumulative 4-week incidence at study points for Confirmed COVID-19 cases per 1,000 residents
Outcome measures
| Measure |
ECHO Plus
n=64 Nursing home
Nursing homes in this arm will receive the intervention via real-time, interactive videoconferencing using Zoom at no cost to participants. Sessions will be 90 minutes in duration and held weekly for 6 months (25 sessions total) at regularly scheduled times. Participants in this arm will receive a 2 month (8 sessions total) refresher course in Fall 2021. Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation
Project ECHO: Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation. This differentiates ECHO from traditional learning and facilitates rapid dissemination of medical knowledge and increased capacity to deliver best-practice care.studying innovative approaches.
|
ECHO
n=64 Nursing home
Nursing homes in this arm will receive the intervention via real-time, interactive videoconferencing using Zoom at no cost to participants. Sessions will be 90 minutes in duration and held weekly for 6 months (25 sessions total) at regularly scheduled times. Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation
Project ECHO: Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation. This differentiates ECHO from traditional learning and facilitates rapid dissemination of medical knowledge and increased capacity to deliver best-practice care.studying innovative approaches.
|
|---|---|---|
|
Infection Rate
Baseline
|
141.91 infections per 1,000 residents in 4 week
Standard Deviation 266.23
|
106.57 infections per 1,000 residents in 4 week
Standard Deviation 192.49
|
|
Infection Rate
4m
|
1.54 infections per 1,000 residents in 4 week
Standard Deviation 6.62
|
2.86 infections per 1,000 residents in 4 week
Standard Deviation 14.11
|
|
Infection Rate
6m
|
2.08 infections per 1,000 residents in 4 week
Standard Deviation 16.67
|
0.83 infections per 1,000 residents in 4 week
Standard Deviation 5.04
|
|
Infection Rate
12m
|
28.01 infections per 1,000 residents in 4 week
Standard Deviation 54.48
|
26.56 infections per 1,000 residents in 4 week
Standard Deviation 50.17
|
|
Infection Rate
18m
|
33.07 infections per 1,000 residents in 4 week
Standard Deviation 66.81
|
30.5 infections per 1,000 residents in 4 week
Standard Deviation 74.18
|
SECONDARY outcome
Timeframe: Baseline, 4, 6, 12, 18 monthsPopulation: Nursing homes were assigned to Arms/Groups, participant level data is not available
Number of COVID-19 hospitalizations from enrolled nursing homes, as measured by Cumulative 4-week incidence at study points for Total COVID-19 admissions
Outcome measures
| Measure |
ECHO Plus
n=64 Nursing home
Nursing homes in this arm will receive the intervention via real-time, interactive videoconferencing using Zoom at no cost to participants. Sessions will be 90 minutes in duration and held weekly for 6 months (25 sessions total) at regularly scheduled times. Participants in this arm will receive a 2 month (8 sessions total) refresher course in Fall 2021. Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation
Project ECHO: Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation. This differentiates ECHO from traditional learning and facilitates rapid dissemination of medical knowledge and increased capacity to deliver best-practice care.studying innovative approaches.
|
ECHO
n=62 Nursing home
Nursing homes in this arm will receive the intervention via real-time, interactive videoconferencing using Zoom at no cost to participants. Sessions will be 90 minutes in duration and held weekly for 6 months (25 sessions total) at regularly scheduled times. Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation
Project ECHO: Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation. This differentiates ECHO from traditional learning and facilitates rapid dissemination of medical knowledge and increased capacity to deliver best-practice care.studying innovative approaches.
|
|---|---|---|
|
Hospitalization
6m
|
5.55 per 1,000 residents in 4 weeks
Standard Deviation 30.40
|
5.18 per 1,000 residents in 4 weeks
Standard Deviation 37.47
|
|
Hospitalization
12m
|
24.57 per 1,000 residents in 4 weeks
Standard Deviation 113.55
|
7.87 per 1,000 residents in 4 weeks
Standard Deviation 24.71
|
|
Hospitalization
18m
|
7.27 per 1,000 residents in 4 weeks
Standard Deviation 21.31
|
13.58 per 1,000 residents in 4 weeks
Standard Deviation 55.54
|
|
Hospitalization
Baseline
|
40.05 per 1,000 residents in 4 weeks
Standard Deviation 83.13
|
39.12 per 1,000 residents in 4 weeks
Standard Deviation 83.88
|
|
Hospitalization
4m
|
3.09 per 1,000 residents in 4 weeks
Standard Deviation 14.01
|
4.72 per 1,000 residents in 4 weeks
Standard Deviation 21.33
|
SECONDARY outcome
Timeframe: Baseline, 4, 6, 12, 18 monthsPopulation: Nursing homes were assigned to Arms/Groups, participant level data is not available
Number of COVID-19 deaths from enrolled nursing homes, as measured by Cumulative 4-week incidence at study points for Total COVID-19 deaths
Outcome measures
| Measure |
ECHO Plus
n=64 Nursing home
Nursing homes in this arm will receive the intervention via real-time, interactive videoconferencing using Zoom at no cost to participants. Sessions will be 90 minutes in duration and held weekly for 6 months (25 sessions total) at regularly scheduled times. Participants in this arm will receive a 2 month (8 sessions total) refresher course in Fall 2021. Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation
Project ECHO: Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation. This differentiates ECHO from traditional learning and facilitates rapid dissemination of medical knowledge and increased capacity to deliver best-practice care.studying innovative approaches.
|
ECHO
n=62 Nursing home
Nursing homes in this arm will receive the intervention via real-time, interactive videoconferencing using Zoom at no cost to participants. Sessions will be 90 minutes in duration and held weekly for 6 months (25 sessions total) at regularly scheduled times. Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation
Project ECHO: Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation. This differentiates ECHO from traditional learning and facilitates rapid dissemination of medical knowledge and increased capacity to deliver best-practice care.studying innovative approaches.
|
|---|---|---|
|
Death
4m
|
0.82 per 1,000 residents in 4 weeks
Standard Deviation 4.39
|
0.00 per 1,000 residents in 4 weeks
Standard Deviation 0.00
|
|
Death
6m
|
0.46 per 1,000 residents in 4 weeks
Standard Deviation 2.61
|
0.30 per 1,000 residents in 4 weeks
Standard Deviation 2.35
|
|
Death
12m
|
3.60 per 1,000 residents in 4 weeks
Standard Deviation 12.51
|
3.71 per 1,000 residents in 4 weeks
Standard Deviation 11.37
|
|
Death
18m
|
2.00 per 1,000 residents in 4 weeks
Standard Deviation 7.28
|
0.19 per 1,000 residents in 4 weeks
Standard Deviation 1.49
|
|
Death
Baseline
|
30.22 per 1,000 residents in 4 weeks
Standard Deviation 61.59
|
31.98 per 1,000 residents in 4 weeks
Standard Deviation 66.2
|
SECONDARY outcome
Timeframe: Baseline, 4, 6, 12, 18 monthsPopulation: Nursing homes were assigned to Arms/Groups, participant level data is not available
Number of flu-like illnesses reported from enrolled nursing homes, as measured by Cumulative 4-week incidence at study points for Total confirmed new influenza per 1,000 residents in 4 weeks
Outcome measures
| Measure |
ECHO Plus
n=64 Nursing home
Nursing homes in this arm will receive the intervention via real-time, interactive videoconferencing using Zoom at no cost to participants. Sessions will be 90 minutes in duration and held weekly for 6 months (25 sessions total) at regularly scheduled times. Participants in this arm will receive a 2 month (8 sessions total) refresher course in Fall 2021. Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation
Project ECHO: Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation. This differentiates ECHO from traditional learning and facilitates rapid dissemination of medical knowledge and increased capacity to deliver best-practice care.studying innovative approaches.
|
ECHO
n=62 Nursing home
Nursing homes in this arm will receive the intervention via real-time, interactive videoconferencing using Zoom at no cost to participants. Sessions will be 90 minutes in duration and held weekly for 6 months (25 sessions total) at regularly scheduled times. Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation
Project ECHO: Project ECHO utilizes case-based, collaborative learning to support discussion of learners' challenges and barriers to guideline implementation. This differentiates ECHO from traditional learning and facilitates rapid dissemination of medical knowledge and increased capacity to deliver best-practice care.studying innovative approaches.
|
|---|---|---|
|
Flu-like Illness
Baseline
|
0.65 per 1,000 residents in 4 weeks
Standard Deviation 5.21
|
0.00 per 1,000 residents in 4 weeks
Standard Deviation 0.00
|
|
Flu-like Illness
4m
|
0.00 per 1,000 residents in 4 weeks
Standard Deviation 0.00
|
0.00 per 1,000 residents in 4 weeks
Standard Deviation 0.00
|
|
Flu-like Illness
6m
|
0.00 per 1,000 residents in 4 weeks
Standard Deviation 0.00
|
0.62 per 1,000 residents in 4 weeks
Standard Deviation 4.88
|
|
Flu-like Illness
12m
|
0.35 per 1,000 residents in 4 weeks
Standard Deviation 2.78
|
1.36 per 1,000 residents in 4 weeks
Standard Deviation 8.01
|
|
Flu-like Illness
18m
|
0.00 per 1,000 residents in 4 weeks
Standard Deviation 0.00
|
0.00 per 1,000 residents in 4 weeks
Standard Deviation 0.00
|
Adverse Events
ECHO Plus
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
ECHO
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Dr. Jennifer Kraschnewski
Penn State College of Medicine
Phone: 717-531-8161
Email: [email protected]
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place