International Spontaneous Coronary Artery Dissection (SCAD) "iSCAD" Registry
NCT ID: NCT04496687
Last Updated: 2024-12-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
1000 participants
OBSERVATIONAL
2019-03-08
2025-12-31
Brief Summary
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The ultimate goal of iSCAD Registry is to facilitate the development of best practices and clinical guidelines for preventing SCAD or its recurrence. This observational study will be prospective and retrospective in its recruitment and will collect clinical information to better understand the natural history and prognosis for SCAD.
Detailed Description
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SCAD strikes generally healthy, younger individuals (average age 42) who do not have traditional cardiac risk factors. Warning signs of SCAD encompass the full range of ACS and MI symptoms, from vague to classic. The cause of SCAD is currently unknown and the psychosocial impact of SCAD is traumatizing. The work of the iSCAD Registry will encompass the physical and psychosocial study of SCAD.
Conditions
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Keywords
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Study Design
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COHORT
OTHER
Eligibility Criteria
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Inclusion Criteria
1. Inpatient wards of the enrolling medical centers during the acute presentation of SCAD, or
2. Outpatient cardiovascular clinics of enrolling medical centers.
Participants must be:
* 18 years of age or older
* Diagnosis of SCAD or history of SCAD based on coronary angiography, either catheter-based or coronary CTA
* Suspected SCAD by coronary angiography
Exclusion Criteria
2. Inability to provide informed consent
3. Inability to complete study-related patient questionnaires
4. Inability to understand and complete patient questionnaires independently
18 Years
ALL
No
Sponsors
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PERFUSE Study Group
UNKNOWN
SCAD Alliance
OTHER
Responsible Party
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Principal Investigators
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Esther Kim, MD
Role: STUDY_CHAIR
Chair, Steering Committee
Malissa Wood, MD
Role: PRINCIPAL_INVESTIGATOR
Member, Steering Committee
Sahar Naderi, MD
Role: PRINCIPAL_INVESTIGATOR
Member, Steering Committee
Locations
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Cedars Sinai
Los Angeles, California, United States
UCLA (University of California, Los Angeles)
Los Angeles, California, United States
Kaiser Permanente Northern California
San Francisco, California, United States
University of Colorado
Aurora, Colorado, United States
Hartford Hospital
Hartford, Connecticut, United States
University of South Florida
Tampa, Florida, United States
Emory Healthcare System
Atlanta, Georgia, United States
Northwestern Medicine
Chicago, Illinois, United States
University of Kentucky
Lexington, Kentucky, United States
Johns Hopkins
Baltimore, Maryland, United States
Massachusetts General Hospital
Boston, Massachusetts, United States
St. Luke's Mid America
Kansas City, Missouri, United States
Washington University
St Louis, Missouri, United States
Dartmouth-Hitchcock
Lebanon, New Hampshire, United States
Catholic Medical Center
Manchester, New Hampshire, United States
Mount Sinai
New York, New York, United States
Columbia University Medical Center
New York, New York, United States
Atrium Health Sanger Heart and Vascular Institute
Charlotte, North Carolina, United States
University Hospitals--Case Western
Cleveland, Ohio, United States
Oklahoma Heart
Oklahoma City, Oklahoma, United States
Providence
Portland, Oregon, United States
University of Pennsylvania
Philadelphia, Pennsylvania, United States
Allegheny General Hospital, Allegheny Health Network
Pittsburgh, Pennsylvania, United States
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, United States
Vanderbilt University Medical Center
Nashville, Tennessee, United States
UT Southwestern
Dallas, Texas, United States
Intermountain
Murray, Utah, United States
University of Virginia
Charlottesville, Virginia, United States
Inova Heart & Vascular Institute
Fairfax, Virginia, United States
University of Washington Medicine
Seattle, Washington, United States
Victor Chang Cardiac Research Institute
Darlinghurst, New South Wales, Australia
Countries
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Central Contacts
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Facility Contacts
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Ana Iribarren, MD
Role: primary
Tim Canan, MD
Role: primary
Marcie Calfon Press, MD
Role: backup
Sahar Naderi, MD
Role: primary
Connie Hess, MD
Role: primary
Kylie Boynton
Role: backup
Stephanie Saucier, MD
Role: primary
Erika Zahina, MD
Role: backup
Daniela Crousillat, MD
Role: primary
Bryan Wells, MD
Role: primary
Mutsa Seremwe
Role: backup
Ranya Sweis, MD
Role: primary
Jeff Trost, MD
Role: primary
Anum Minhas, MD
Role: backup
Nandita Scott, MD
Role: primary
Anna Grodzinsky, MD
Role: primary
Carmen Butcher
Role: backup
Hannah Chaudry, MD
Role: primary
Michelle Ouellette, MD
Role: primary
Jennifer Driscoll
Role: backup
Daniella Kadian-Dodov, MD
Role: primary
Kimberly Capustin
Role: backup
Sonia Tolani, MD
Role: primary
Esther SH Kim, MD, MPH
Role: primary
Heather Gornik, MD
Role: primary
Nasla Tonni
Role: backup
Lori Tam, MD
Role: primary
Shawnna Verburg
Role: backup
Jennifer Lewey, MD
Role: primary
Tiffany Sharkosi
Role: backup
Indu Poornima, MD
Role: primary
Agnes Koczo, MD
Role: primary
Kathryn Lindley, MD
Role: primary
Olivia Patridge
Role: backup
Dharam Kumbhani, MD
Role: primary
Rina Mauricio, MD
Role: backup
James Orford, MD
Role: primary
Lorlie Evans
Role: backup
Patricia Rodriguez Lozano, MD
Role: primary
Linda Bryceland
Role: backup
Garima Sharma, MD
Role: primary
Kelley Branch, MD
Role: primary
Kate Kearney, MD
Role: backup
Jason C Kovacic, MBBS, PhD
Role: primary
Stephanie Hessleson, PhD
Role: backup
References
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Sumner JA, Kim ESH, Wood MJ, Chi G, Nolen J, Grodzinsky A, Gornik HL, Kadian-Dodov D, Wells BJ, Hess CN, Lewey J, Tam L, Henkin S, Orford J, Wells G, Kumbhani DJ, Lindley KJ, Gibson CM, Leon KK, Naderi S. Posttraumatic Stress Disorder After Spontaneous Coronary Artery Dissection: A Report of the International Spontaneous Coronary Artery Dissection Registry. J Am Heart Assoc. 2024 Apr 2;13(7):e032819. doi: 10.1161/JAHA.123.032819. Epub 2024 Mar 27.
Related Links
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iSCAD Registry Home Page
iSCAD Registry FAQs and sponsor page
Other Identifiers
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20190308
Identifier Type: -
Identifier Source: org_study_id