Ambulance Calls for Substance Use and Alcohol in a Pandemic (ASAP)
NCT ID: NCT04474444
Last Updated: 2024-12-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
55000 participants
OBSERVATIONAL
2019-03-23
2021-03-23
Brief Summary
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Detailed Description
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A time series analysis will be conducted to examine the calls over the course of the year prior to the lockdown, and then compare this to the period of lockdown and following months. This will use the 'Interrupted Time Series' (ITS) approach. To explore this regression models will be built that examine the causal models for attendance prior to the pandemic and compared to the lockdown time frame.
A multivariable regression model will be built. Initially a Directed Acyclic Graph (DAG) will allow the identification of confounders and exposures relevant to the model. A logistic regression model will be used to calculate the relative risk of call during lockdown compared to the data prior to lockdown. The model will be fit using p\<0.05 as the definition of statistical significance.
Descriptive statistics, trend analysis and predictive analysis will be conducted on the data set to determine trends across time, factors that predict patients requiring ambulance attendance, and factors that predict treatment outcomes. Missing data will be examined for systematic bias, and where found to be missing at random will be excluded from analysis. Where not missing at random, sensitivity analysis will be conducted.
Analysis will examine covariates. Age will be defined as single year continuous variable and examined in categories such as 5-year age groups. Ethnicity will be categorised as groups, such as black, Asian, other minority and mixed ethnic groups will be explored. Census data such as the deprivation, rurality, income, employment, disability and education will look at the decile as defined.
Conditions
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Study Design
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CASE_ONLY
RETROSPECTIVE
Study Groups
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Hear and treat
phone call, treatment, not attended
No interventions assigned to this group
See and treat
Ambulance crew attended
attendance by ambulance crew
hear, attendance, convey
Interventions
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attendance by ambulance crew
hear, attendance, convey
Eligibility Criteria
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Inclusion Criteria
* Patient requested ambulance attendance between 23rd March 2019 and 22nd March 2021
* The patient record is held by East Midlands Ambulance Service
* Patient records that have recorded a clinical impression related to alcohol and substance use will be included in the data set alongside a word search in the free text response box for the following words/phrases: narcotic, spice, mamba, alcohol, substance use, drug use, illicit drug, overdose, intoxication, intoxicated, drunk, high.
Exclusion Criteria
* The patient record is not accessible via EMAS
ALL
Yes
Sponsors
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University of Lincoln
OTHER
Responsible Party
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Principal Investigators
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Graham Law, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Lincoln
Locations
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University of Lincoln
Lincoln, , United Kingdom
Countries
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Other Identifiers
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ASAP01
Identifier Type: -
Identifier Source: org_study_id