Peripheral Nerve Block Techniques During Cleft Palate

NCT ID: NCT04467463

Last Updated: 2020-10-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-11-01

Study Completion Date

2020-12-31

Brief Summary

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Regional blocks are commonly used in pediatric anesthesia to achieve adequate postoperative analgesia. Suprazygomatic Maxillary nerve block (SMN) and Greater Palatine nerve block (GPN) are regional blocks described for use during cleft palate (CP) repair surgery.The aim of this study was to compare the analgesic effect as well as the incidence of complications associated with the use of bilateral GPN and bilateral SMN blocks in children undergoing palatoplasty surgery.

Detailed Description

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Conditions

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Postoperative Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

The two study groups were:

* Group GPN, 20 patients received bilateral greater palatine nerve block.
* Group SMN, 20 patients received bilateral suprazygomatic maxillary nerve block.
Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Caregivers
masking from the aim of the study

Study Groups

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GPN

administrated bilateral greater palatine nerve block using levobupivacaine 0.25%

Group Type EXPERIMENTAL

peripheral nerve block by 0.25% levobupivacaine

Intervention Type PROCEDURE

SUBMANDIBULAR nerve block will be performed using a 25G 90 mm beveled needle . the entry point of the needle will be situated at the angle formed by the superior edge of the zygomatic arch below and the posterior orbital rim forward .The needle will be inserted perpendicular to the skin and advanced approximately 20 mm depth to reach the greater wing of the sphenoid deep to the pterygopalatine fossa. Injection of 1ml of 0.25% levobupivacaine will be done over 20 seconds afterensuring negative blood aspiration .greater Palatine Nerve will be blocked bilaterally as it leaves on palatal side through the foramen on the opposite direction of the anterior part of the 3rd molar orthe posterior part of the 2nd molar tooth.

SMN

administrated bilateral suprazygomatic nerve block using levobupivacaine 0.25%.

Group Type EXPERIMENTAL

peripheral nerve block by 0.25% levobupivacaine

Intervention Type PROCEDURE

SUBMANDIBULAR nerve block will be performed using a 25G 90 mm beveled needle . the entry point of the needle will be situated at the angle formed by the superior edge of the zygomatic arch below and the posterior orbital rim forward .The needle will be inserted perpendicular to the skin and advanced approximately 20 mm depth to reach the greater wing of the sphenoid deep to the pterygopalatine fossa. Injection of 1ml of 0.25% levobupivacaine will be done over 20 seconds afterensuring negative blood aspiration .greater Palatine Nerve will be blocked bilaterally as it leaves on palatal side through the foramen on the opposite direction of the anterior part of the 3rd molar orthe posterior part of the 2nd molar tooth.

Interventions

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peripheral nerve block by 0.25% levobupivacaine

SUBMANDIBULAR nerve block will be performed using a 25G 90 mm beveled needle . the entry point of the needle will be situated at the angle formed by the superior edge of the zygomatic arch below and the posterior orbital rim forward .The needle will be inserted perpendicular to the skin and advanced approximately 20 mm depth to reach the greater wing of the sphenoid deep to the pterygopalatine fossa. Injection of 1ml of 0.25% levobupivacaine will be done over 20 seconds afterensuring negative blood aspiration .greater Palatine Nerve will be blocked bilaterally as it leaves on palatal side through the foramen on the opposite direction of the anterior part of the 3rd molar orthe posterior part of the 2nd molar tooth.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* ASA I-III scheduled to undergo palatoplasty

Exclusion Criteria

* bleeding disorders,
* skin lesions or wounds at site of proposed needle insertion,
* congenital heart disease,
* respiratory or
* cardiovascular disorders,
* children scheduled for combined procedures like palatoplasty with cheiloplasty or submucosal alveolar bone grafting,
* known hypersensitivity to local anesthetics or opioids and
* lack of parental consent.
Minimum Eligible Age

6 Months

Maximum Eligible Age

5 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Mohamed Elsonbaty

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Cairo University hospitals

Cairo, Manial, Egypt

Site Status RECRUITING

anesthesia department at Cairo University

Cairo, , Egypt

Site Status COMPLETED

Countries

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Egypt

Central Contacts

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Sherif Abdullah Mohamed, M.D.

Role: CONTACT

+201002013497 ext. 02

Facility Contacts

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Ayman Hussam, M.D.

Role: primary

01004389020

References

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Pain terms: a list with definitions and notes on usage. Recommended by the IASP Subcommittee on Taxonomy. Pain. 1979 Jun;6(3):249. No abstract available.

Reference Type BACKGROUND
PMID: 460932 (View on PubMed)

Lee SJ, Ralston HJ, Drey EA, Partridge JC, Rosen MA. Fetal pain: a systematic multidisciplinary review of the evidence. JAMA. 2005 Aug 24;294(8):947-54. doi: 10.1001/jama.294.8.947.

Reference Type BACKGROUND
PMID: 16118385 (View on PubMed)

3. Tremlett M. Anaesthesia for cleft lip and palate surgery. Curr Anaesth Crit Care. 2004;15:309-16.

Reference Type BACKGROUND

Diewert VM. Development of human craniofacial morphology during the late embryonic and early fetal periods. Am J Orthod. 1985 Jul;88(1):64-76. doi: 10.1016/0002-9416(85)90107-1.

Reference Type BACKGROUND
PMID: 3860013 (View on PubMed)

Other Identifiers

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N-98-2019

Identifier Type: -

Identifier Source: org_study_id