Sofosbuvir in Treatment of COVID 19

NCT ID: NCT04460443

Last Updated: 2020-12-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE2/PHASE3

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-08-01

Study Completion Date

2021-08-31

Brief Summary

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Sofosbuvir containing treatment in treatment of COVID 19 Egyptian patients

Detailed Description

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Sofosbuvir containing treatment of COVID 19 Egyptian patients: a randomized-controlled trial

Conditions

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COVID

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Sofosbuvir and ledipsavir

Sofosbuvir and ledipsavir plus standard of care treatment.

Group Type EXPERIMENTAL

Sofosbuvir ledipsavir

Intervention Type DRUG

Sofosbuvir ledipsavir once daily

Sofosbuvir and Daklatasuvir

Sofosbuvir and Daklatasuvir plus standard of card treatment..

Group Type EXPERIMENTAL

sofosbuvir

Intervention Type DRUG

Sofosbuvir once daily

Daclatasvir

Intervention Type DRUG

Daklatasuvir tablets

Standard treatment

Standard treatment alone

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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sofosbuvir

Sofosbuvir once daily

Intervention Type DRUG

Sofosbuvir ledipsavir

Sofosbuvir ledipsavir once daily

Intervention Type DRUG

Daclatasvir

Daklatasuvir tablets

Intervention Type DRUG

Other Intervention Names

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Mpiviropack, Sovaldy, soflanork mpiviropack plus daklinza

Eligibility Criteria

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Inclusion Criteria

* Covid positive patients.

Exclusion Criteria

* Contraindication to sofosbuvir or ribavirin.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tanta University

OTHER

Sponsor Role lead

Responsible Party

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Sherief Abd-Elsalam

Ass. Prof. Tropical Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Marwa Salama, Consultant

Role: PRINCIPAL_INVESTIGATOR

Tanta University - Faculty of Medicine

Locations

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Sherief Abd-Elsalam

Tanta, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Sherief Abd-Elsalam, ass. prof.

Role: CONTACT

Phone: 00201147773440

Email: [email protected]

sherief abd-elsalan, ass. prof.

Role: CONTACT

Phone: 00201147773440

Email: [email protected]

Facility Contacts

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Sherief Abd-Elsalam, Ass. Prof.

Role: primary

Other Identifiers

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sofosbuvir

Identifier Type: -

Identifier Source: org_study_id