Cognitive Behavioral Sleep Intervention for Prevention of Type 2 Diabetes

NCT ID: NCT04457440

Last Updated: 2021-10-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

SUSPENDED

Clinical Phase

NA

Total Enrollment

36 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-07-01

Study Completion Date

2021-12-30

Brief Summary

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The proposed study aims to evaluate if improving sleep could enhance the intensive lifestyle intervention for improving weight loss and glycemic control in prediabetic individuals who have insomnia with short sleep duration. A cognitive behavioral intervention for insomnia with adjustments aimed at increasing sleep duration (CBT-Sleep) will be used for this study.

Detailed Description

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Conditions

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PreDiabetes Insomnia Sleep Deprivation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Intensive Lifestyle Intervention (ILI)

The ILI will consist of 8 group-based 90-min sessions focusing on modifying dietary and exercise habits with the goal of reducing 450kcal of daily calories and increasing physical activity to 150 minutes of exercise per week.

Group Type ACTIVE_COMPARATOR

Intensive Lifestyle Intervention

Intervention Type BEHAVIORAL

This intervention is an abbreviated version of the Diabetes Prevention Program, which has been shown to be effective in reducing the risk of developing type 2 diabetes.

ILI enhanced with cognitive behavioral sleep intervention

The ILI+Sleep intervention will consist of the same 8 sessions of ILI with additions of sleep components in each session.

Group Type EXPERIMENTAL

Intensive Lifestyle Intervention enhanced with Cognitive Behavioral Sleep Intervention

Intervention Type BEHAVIORAL

This intervention will consist of the same 8 sessions of ILI with additions of sleep components in each session. The additional sleep components will include (a) psychoeducation about the importance of sleep in weight control and glycemic control, (b) sleep hygiene, (c) stimulus control, (d) modifying maladaptive beliefs about sleep, (e) and, setting individualized sleep schedule and reviewing sleep schedule.

Interventions

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Intensive Lifestyle Intervention

This intervention is an abbreviated version of the Diabetes Prevention Program, which has been shown to be effective in reducing the risk of developing type 2 diabetes.

Intervention Type BEHAVIORAL

Intensive Lifestyle Intervention enhanced with Cognitive Behavioral Sleep Intervention

This intervention will consist of the same 8 sessions of ILI with additions of sleep components in each session. The additional sleep components will include (a) psychoeducation about the importance of sleep in weight control and glycemic control, (b) sleep hygiene, (c) stimulus control, (d) modifying maladaptive beliefs about sleep, (e) and, setting individualized sleep schedule and reviewing sleep schedule.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* (a) Hong Kong residents,
* (b) BMI \> 23kg/m2,
* (c) aged 18 to 65 year-old,
* (d) have prediabetes, defined by a plasma fasting glucose concentration of 5.6 to 6.9 mmol/L, impaired glucose tolerance (2hglucose 7.8-11.0 on OGTT), or HbA1c 5.7-6.4%,
* (e) have average habitual sleep duration \< 6.5 hours, confirmed by actigraphy measure of sleep for 2 weeks or have insomnia, confirmed in a clinical sleep interview and actigraph-measure of greater than 30 minutes of sleep onset latency or nighttime awakening for 3 nights or more per week

Exclusion Criteria

* (a) have unmanaged sleep apnea or other sleep disorders,
* (b) have any current severe mental illnesses,
* (c) have any medical conditions or medication use that could undermine the efficacy of the sleep intervention,
* (d) have shift work schedules,
* (e) have any environmental constraints on the feasibility of implementing a sleep schedule of at least 7.5 hours
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The University of Hong Kong

OTHER

Sponsor Role lead

Responsible Party

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Dr. Chan Wai Sze

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Wai Sze Chan, PhD

Role: PRINCIPAL_INVESTIGATOR

The University of Hong Kong

Locations

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Queen Mary Hpspital

Hong Kong, , Hong Kong

Site Status

The University of Hong Kong

Hong Kong, , Hong Kong

Site Status

Countries

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Hong Kong

Other Identifiers

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UW20-245

Identifier Type: OTHER

Identifier Source: secondary_id

EA1909037

Identifier Type: -

Identifier Source: org_study_id