Trial Outcomes & Findings for Improving Health Insurance Experiences for Adolescent and Young Adult Cancer Patients (NCT NCT04448678)

NCT ID: NCT04448678

Last Updated: 2024-01-05

Results Overview

Comparing total number of individuals enrolled and randomized vs completed study (completion of both surveys for control or both surveys and all of the sessions for intervention.)

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

86 participants

Primary outcome timeframe

Post-Assessment survey (Weeks 13 (+/- 2 weeks))

Results posted on

2024-01-05

Participant Flow

We decided to overshoot our original target just to have the extra data.

Participant milestones

Participant milestones
Measure
HIEP Intervention
Participants will be randomized to receive the insurance navigation intervention from patient navigators, which includes four, one hour long, educational learning sessions. Randomization will be done by age at diagnosis and site. Health Insurance Education Program (HIEP): \[See arm/group descriptions\]
Usual Care
Participants will be randomized to receive standard navigation provided by patient navigators ("usual care"). Usual Care: \[See arm/group descriptions\]
Overall Study
STARTED
45
41
Overall Study
COMPLETED
25
39
Overall Study
NOT COMPLETED
20
2

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Some of the participants (n=4) did not fill in all of the fields required for us to analyze their COST score.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
HIEP Intervention
n=45 Participants
Participants will be randomized to receive the insurance navigation intervention from patient navigators, which includes four, one hour long, educational learning sessions. Randomization will be done by age at diagnosis and site. Health Insurance Education Program (HIEP): \[See arm/group descriptions\]
Usual Care
n=41 Participants
Participants will be randomized to receive standard navigation provided by patient navigators ("usual care"). Usual Care: \[See arm/group descriptions\]
Total
n=86 Participants
Total of all reporting groups
Age, Categorical
<=18 years
0 Participants
n=45 Participants
0 Participants
n=41 Participants
0 Participants
n=86 Participants
Age, Categorical
Between 18 and 65 years
45 Participants
n=45 Participants
41 Participants
n=41 Participants
86 Participants
n=86 Participants
Age, Categorical
>=65 years
0 Participants
n=45 Participants
0 Participants
n=41 Participants
0 Participants
n=86 Participants
Age, Continuous
28.96 Years
STANDARD_DEVIATION 7.19 • n=45 Participants
28.71 Years
STANDARD_DEVIATION 6.15 • n=41 Participants
28.84 Years
STANDARD_DEVIATION 6.68 • n=86 Participants
Age, Customized
Younger Group Age 18-25
17 Participants
n=45 Participants
13 Participants
n=41 Participants
30 Participants
n=86 Participants
Age, Customized
Older Group Age 26-39
28 Participants
n=45 Participants
28 Participants
n=41 Participants
56 Participants
n=86 Participants
Sex: Female, Male
Female
28 Participants
n=45 Participants
31 Participants
n=41 Participants
59 Participants
n=86 Participants
Sex: Female, Male
Male
17 Participants
n=45 Participants
10 Participants
n=41 Participants
27 Participants
n=86 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
6 Participants
n=45 Participants
10 Participants
n=41 Participants
16 Participants
n=86 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
39 Participants
n=45 Participants
30 Participants
n=41 Participants
69 Participants
n=86 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=45 Participants
1 Participants
n=41 Participants
1 Participants
n=86 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=45 Participants
0 Participants
n=41 Participants
0 Participants
n=86 Participants
Race (NIH/OMB)
Asian
2 Participants
n=45 Participants
2 Participants
n=41 Participants
4 Participants
n=86 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=45 Participants
0 Participants
n=41 Participants
0 Participants
n=86 Participants
Race (NIH/OMB)
Black or African American
0 Participants
n=45 Participants
0 Participants
n=41 Participants
0 Participants
n=86 Participants
Race (NIH/OMB)
White
36 Participants
n=45 Participants
26 Participants
n=41 Participants
62 Participants
n=86 Participants
Race (NIH/OMB)
More than one race
1 Participants
n=45 Participants
2 Participants
n=41 Participants
3 Participants
n=86 Participants
Race (NIH/OMB)
Unknown or Not Reported
6 Participants
n=45 Participants
11 Participants
n=41 Participants
17 Participants
n=86 Participants
Region of Enrollment
United States
45 participants
n=45 Participants
41 participants
n=41 Participants
86 participants
n=86 Participants
COmprehensive Score for financial Toxicity (COST)
19.72 Score on a scale
STANDARD_DEVIATION 9.72 • n=43 Participants • Some of the participants (n=4) did not fill in all of the fields required for us to analyze their COST score.
20.18 Score on a scale
STANDARD_DEVIATION 12.20 • n=39 Participants • Some of the participants (n=4) did not fill in all of the fields required for us to analyze their COST score.
19.94 Score on a scale
STANDARD_DEVIATION 10.90 • n=82 Participants • Some of the participants (n=4) did not fill in all of the fields required for us to analyze their COST score.
Health Insurance Literacy Measure (HILM)
22.64 Score on a scale
STANDARD_DEVIATION 5.21 • n=44 Participants • Some of the participants (n=1) did not fill in all of the fields required for us to analyze their HILM score.
22.46 Score on a scale
STANDARD_DEVIATION 5.81 • n=41 Participants • Some of the participants (n=1) did not fill in all of the fields required for us to analyze their HILM score.
22.55 Score on a scale
STANDARD_DEVIATION 5.48 • n=85 Participants • Some of the participants (n=1) did not fill in all of the fields required for us to analyze their HILM score.

PRIMARY outcome

Timeframe: Post-Assessment survey (Weeks 13 (+/- 2 weeks))

Population: Insured cancer patients between the ages of 18-39 who are within their first year of treatment at Huntsman Cancer Institute or the Intermountain Network.

Comparing total number of individuals enrolled and randomized vs completed study (completion of both surveys for control or both surveys and all of the sessions for intervention.)

Outcome measures

Outcome measures
Measure
Usual Care
n=41 Participants
Number of participants who were randomized into care as usual versus those who completed the study (follow up survey).
HIEP Intervention
n=45 Participants
Number of participants who were randomized into the Health Insurance Educational Program versus those who completed the study (all 4 sessions and the follow up survey).
Combined
All participants
Feasibility Measurement
39 Participants
25 Participants

PRIMARY outcome

Timeframe: Post-Assessment interview (Weeks 18 (+/- 2 weeks))

Population: Analysis of participants satisfaction from questions asked in the exit interview. Only including participants who were randomized into the intervention, then the exit interviews, and completed at least one session of the HIEP.

Questions surrounding satisfaction with the HIEP. These will be asked at the post-assessment interview and will consist of participants responses surrounding satisfaction with the HIEP. We will report percentages of participants who did 1 or more session and reported satisfaction with the HIEP.

Outcome measures

Outcome measures
Measure
Usual Care
n=10 Participants
Number of participants who were randomized into care as usual versus those who completed the study (follow up survey).
HIEP Intervention
Number of participants who were randomized into the Health Insurance Educational Program versus those who completed the study (all 4 sessions and the follow up survey).
Combined
All participants
Acceptability - Module Satisfaction
10 Participants
0 Participants

PRIMARY outcome

Timeframe: Post-Assessment survey (Weeks 13 (+/- 2 weeks))

Population: Insured cancer patients between the ages of 18-39 who are within their first year of treatment at Huntsman Cancer Institute or the Intermountain Network.

Validated Patient Satisfaction with Navigator Interpersonal Relationship (PSN-I) measure at post assessment survey. This score ranges from 0-45 with higher scores indicating higher satisfaction. We will report the mean and standard deviation.

Outcome measures

Outcome measures
Measure
Usual Care
n=45 Participants
Number of participants who were randomized into care as usual versus those who completed the study (follow up survey).
HIEP Intervention
n=41 Participants
Number of participants who were randomized into the Health Insurance Educational Program versus those who completed the study (all 4 sessions and the follow up survey).
Combined
All participants
Navigator Satisfaction
30.84 score on a scale
Standard Deviation 16.15
30.32 score on a scale
Standard Deviation 12.95

SECONDARY outcome

Timeframe: Baseline (Week 0) and Post Assessment survey (Weeks 13 (+/- 2 weeks))

Population: Insured cancer patients between the ages of 18-39 who are within their first year of treatment at Huntsman Cancer Institute or the Intermountain Network.

Differences between Health Insurance Literacy Measure (HILM) reported at the intro baseline and exit post-assessment survey. For this study, the last two sections (3\&4) of the HILM were used. Scores range from 9-36 with lower scores indicate lower health insurance literacy and worse outcomes. Differences will be examined by age group and by treatment arm. We report mean and standard deviation. Please note that not all participants, filled out all necessary questions at both timepoints to be assessed.

Outcome measures

Outcome measures
Measure
Usual Care
n=36 Participants
Number of participants who were randomized into care as usual versus those who completed the study (follow up survey).
HIEP Intervention
n=36 Participants
Number of participants who were randomized into the Health Insurance Educational Program versus those who completed the study (all 4 sessions and the follow up survey).
Combined
n=72 Participants
All participants
Changes in Efficacy- Health Insurance Literacy
5.39 Score on a scale
Standard Deviation 6.44
2.30 Score on a scale
Standard Deviation 6.06
3.84 Score on a scale
Standard Deviation 6.40

SECONDARY outcome

Timeframe: Baseline (Week 0) and Post Assessment survey (Weeks 13 (+/- 2 weeks))

Population: Insured cancer patients between the ages of 18-39 who are within their first year of treatment at Huntsman Cancer Institute or the Intermountain Network.

Questions surrounding familiarity with the ACA reported at the baseline and post-assessment survey. Values range from 0 to 28 with higher scores indicating better familiarity with ACA concepts. We will report the mean and standard deviation of the difference in response scores between baseline and post assessment for the control and intervention. Please note that not all participants, filled out all necessary questions at both timepoints to be assessed.

Outcome measures

Outcome measures
Measure
Usual Care
n=37 Participants
Number of participants who were randomized into care as usual versus those who completed the study (follow up survey).
HIEP Intervention
n=37 Participants
Number of participants who were randomized into the Health Insurance Educational Program versus those who completed the study (all 4 sessions and the follow up survey).
Combined
n=74 Participants
All participants
Changes in Efficacy- Affordable Care Act (ACA) Familiarity
5.84 Score on a scale
Standard Deviation 6.30
2.03 Score on a scale
Standard Deviation 4.89
3.93 Score on a scale
Standard Deviation 5.92

SECONDARY outcome

Timeframe: Baseline (Week 0) and Post Assessment survey ( Weeks 13 (+/- 2 weeks))

Differences between COmprehensive Score for financial Toxicity (COST) reported at the baseline and post-assessment survey. Values range from 0 to 44 where lower COST scores indicate worse financial toxicity. Differences will be examined by age group and by treatment arm. We will report mean and standard deviation. Please note that not all participants, filled out all necessary questions at both timepoints to be assessed.

Outcome measures

Outcome measures
Measure
Usual Care
n=35 Participants
Number of participants who were randomized into care as usual versus those who completed the study (follow up survey).
HIEP Intervention
n=36 Participants
Number of participants who were randomized into the Health Insurance Educational Program versus those who completed the study (all 4 sessions and the follow up survey).
Combined
n=71 Participants
All participants
Changes in Efficacy-Financial Distress
Younger group (18-25)
3.70 Score on a scale
Standard Deviation 9.59
2.89 Score on a scale
Standard Deviation 9.44
3.32 Score on a scale
Standard Deviation 9.26
Changes in Efficacy-Financial Distress
Older group (26-39)
3.08 Score on a scale
Standard Deviation 8.45
0.741 Score on a scale
Standard Deviation 6.42
1.87 Score on a scale
Standard Deviation 7.48
Changes in Efficacy-Financial Distress
Combined (18-39)
3.25 Score on a scale
Standard Deviation 8.65
1.28 Score on a scale
Standard Deviation 7.20
2.25 Score on a scale
Standard Deviation 7.95

Adverse Events

HIEP Intervention

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Usual Care

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Anne Kirchhoff

University of Utah

Phone: 801-587-4084

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place