Efficacy of Dexmedetomidine Versus Morphine as an Adjunct to Bupivacaine in Caudal Anesthesia.
NCT ID: NCT04445636
Last Updated: 2020-12-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
50 participants
INTERVENTIONAL
2020-06-28
2020-12-10
Brief Summary
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Detailed Description
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Randomization will be achieved by using an online random number generator. Patient codes will be placed into sequentially numbered sealed opaque envelopes by a research assistant who is not involved in the study. An anesthesia resident not involved in patient management will be responsible for opening the envelope. The anesthesia resident will prepare the study drug according to the instructions contained within each envelope and give it to the anesthesiologist.
Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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Dexmedetomidine group
A group which will receive dexamedetomidine as an adjunct to bupivacaine used in caudal anesthesia.
Dexmedetomidine
Caudal block with Dexametomedine as an adjuvant to bupivacaine.
Morphine group
A group which will receive morphine as an adjunct to bupivacaine used in caudal anesthesia.
Morphine
Addition of morphine as adjuvant to bupivacaine during caudal block.
Interventions
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Dexmedetomidine
Caudal block with Dexametomedine as an adjuvant to bupivacaine.
Morphine
Addition of morphine as adjuvant to bupivacaine during caudal block.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Patients undergoing lung cyst excision.
* Patients undergoing Patent Ductus Arteriosus ligation.
Exclusion Criteria
* Preoperative inotropic support
* History of mental retardation or delayed development that may interfere with pain intensity assessment
* Known or suspected coagulopathy,
* Any congenital anomalies of the sacrum or any infection at the site of injection.
* Known or suspected allergy to any of the studied drugs.
1 Year
6 Years
ALL
No
Sponsors
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Cairo University
OTHER
Responsible Party
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Ahmed Abdelaziz Ismail
Director
Principal Investigators
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AHMED ISMAIL, Lecturer
Role: STUDY_DIRECTOR
Cairo University
Locations
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Cairo University Hospitals
Cairo, , Egypt
Countries
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References
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Anand VG, Kannan M, Thavamani A, Bridgit MJ. Effects of dexmedetomidine added to caudal ropivacaine in paediatric lower abdominal surgeries. Indian J Anaesth. 2011 Jul;55(4):340-6. doi: 10.4103/0019-5049.84835.
El Shamaa HA, Ibrahim M. A comparative study of the effect of caudal dexmedetomidine versus morphine added to bupivacaine in pediatric infra-umbilical surgery. Saudi J Anaesth. 2014 Apr;8(2):155-60. doi: 10.4103/1658-354X.130677.
Nguyen KN, Byrd HS, Tan JM. Caudal analgesia and cardiothoracic surgery: a look at postoperative pain scores in a pediatric population. Paediatr Anaesth. 2016 Nov;26(11):1060-1063. doi: 10.1111/pan.12990. Epub 2016 Aug 23.
Other Identifiers
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N239-2020
Identifier Type: -
Identifier Source: org_study_id