Usability, Safety and Efficacy of AspivixTM

NCT ID: NCT04441333

Last Updated: 2020-12-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

13 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-07-01

Study Completion Date

2020-12-02

Brief Summary

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Limited mobility of the uterine cervix and alignment with the vaginal canal is often required during insertion of an intrauterine contraceptive device (IUD). Currently, the available instruments are traumatic tenacula, which could cause pain and bleeding and therefore represent an obstacle for certain patients to pursue their medical follow-up.

AspivixTM is a new device, which enables atraumatic traction of the cervix while respecting its specific semi-circular anatomic shape through a system powered by a vacuum chamber.

The aim of our pilot study is to assess the usability, safety and efficacy of the device.

Note: Study is made of 2 phases (pilot phase followed by a comparative phase). Details regarding comparative study is registered separately.

Detailed Description

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Conditions

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IUD Insertion

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Pilot study: single-arm non-comparative study
Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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AspivixTM cervical vacuum tenaculum

Traction of the cervix for IUD insertion using the AspivixTM cervical vacuum tenaculum.

Group Type EXPERIMENTAL

AspivixTM cervical vacuum tenaculum

Intervention Type DEVICE

Traction of the cervix for IUD insertion using the AspivixTM cervical vacuum tenaculum

Interventions

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AspivixTM cervical vacuum tenaculum

Traction of the cervix for IUD insertion using the AspivixTM cervical vacuum tenaculum

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Participants older than 18 years
* Participants presenting at the outpatient clinic for Mirena IUD insertion.
* Participants able to provide informed consent as documented by signature with at least 24 hours of reflection time
* Good understanding of written and oral speaking used at the centre where the study will be carried out.

Exclusion Criteria

* Participants who are contraindicated for the insertion of the IUD Mirena
* Participants under use of excessive alcohol, narcotics or benzodiazepines prior to procedure
* Participants who do not wish to be informed of a chance discovery
* Participant receiving anaesthetics prior to IUD insertion procedure
* Participants on anticoagulant medication
* Participants under use of an analgesic
* Previous cervical operation
* Severe vaginal bleeding
* Participant previously enrolled in this study
* Cervix diameter smaller than 26 mm
* Mullerian anomalies with two cervices
* Nabothian cyst
* Cervical myomas
* Cervical condylomas
* Squamous intraepithelial lesion (Cervical dysplasia)
* Cervical endometriosis
* Cervical tears
* A well exposed cervix and / or well aligned vaginal and cervical canals where no traction is required for IUD insertion
* Other cervical abnormalities (cervical polyp, cervical lesion, or irregularity) which may contraindicate or complicate IUD insertion
* Large ectopy, for which it is not possible to find a suitable location near the ectopy where native tissue is present
* Large scar tissue, for which it is not possible to find a suitable location near the scar where native tissue is present
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Aspivix SA

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Patrice Mathevet, Prof.

Role: PRINCIPAL_INVESTIGATOR

DFME CHUV Lausanne

Locations

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Department Women, Mother & Child, University Hospital

Lausanne, Canton of Vaud, Switzerland

Site Status

Countries

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Switzerland

References

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Legardeur H, Masiello-Fonjallaz G, Jacot-Guillarmod M, Mathevet P. Safety and Efficacy of an Atraumatic Uterine Cervical Traction Device: A Pilot Study. Front Med (Lausanne). 2021 Dec 23;8:742182. doi: 10.3389/fmed.2021.742182. eCollection 2021.

Reference Type DERIVED
PMID: 35004719 (View on PubMed)

Other Identifiers

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Aspivix_IUD2019_Pilot

Identifier Type: -

Identifier Source: org_study_id