Effect of Behavioral Lifestyle Intervention on Frailty in Older Adults With Diabetes

NCT ID: NCT04440449

Last Updated: 2022-05-24

Study Results

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-07-15

Study Completion Date

2022-04-28

Brief Summary

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The study team want to see if changes in lifestyle and behaviors and self-monitoring of diet and physical activity in older adults who have type 2 Diabetes (T2D) may help to prevent or reduce frailty. Frailty occurs in older adults and leads people to have falls, become disabled, require nursing home placement, and have increased risk of death. T2D is one of the major risk factors for frailty. T2D is a significant problem in older adults and is known to increase the risk of future frailty.

Detailed Description

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Behavioral lifestyle intervention: Participants (N=40) will be randomized to the mHealth+ group Intervention group (Group A; n=20)and mHealth+ individual intervention group (Group B; n=20) group using a randomization table. (1) The mHealth+ group Intervention group (Group A) will receive a modified Look AHEAD behavior lifestyle intervention with smartphone-based self-monitoring of diet and physical activity. This comprises ten group sessions for lifestyle intervention in 6-months. The group will receive three weekly classes in the first month and then bi-weekly classes for month 2-3, and three monthly session in month four, five, and six. The frequency and layout of these classes will allow participants to master new skills gradually, then eventually wean off, and adopt the modified lifestyle as the part of their daily lives. (2) The mHealth+ individual intervention group (Group B) will receive an abbreviated behavior lifestyle intervention with smartphone-based self-monitoring of diet and physical activity in one face-to-face individual session at the beginning of the study. In addition, participants will receive self-study materials, from Look Ahead modules, and a monthly follow-up phone calls for the duration of the study (6-months). The goal for these follow up phone calls are to assess understanding of the modules, to promote continued engagement with the study material, and to provide clarification on materials as needed. Participants in the mHealth+ group Intervention group (Group A) and mHealth+ individual intervention group (Group B will receive instruction on how to download an app to help them record their diet and physical activity at the beginning of the study.

Fitbit offers a simple, easy-to-use tool for tracking food and physical activity. It helps set daily calorie budget, and set and work towards goals for nutrient intake, weight loss, exercise, and more. https://www.fitbit.com/inspire 04.12.20: Due to SARS-CoV2 (COVID-19) and social distancing order, the study team are adding hemoglobin Hba1c home test.

Conditions

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Frailty Weight, Body Type 2 Diabetes

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

* Group A - Mobile Health + group intervention
* Group B (control arm)
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Behavioral Lifestyle Intervention

The participants will receive behavioral lifestyle intervention with a smartphone-based self-monitoring for diet and physical activity. This group also includes a total of 10 Group sessions over 6 months.

Group Type EXPERIMENTAL

Lifestyle App

Intervention Type BEHAVIORAL

A mobile app used to assist with lifestyle changes

Look AHEAD behavior lifestyle intervention

Intervention Type BEHAVIORAL

A modified Look AHEAD behavior lifestyle intervention with smartphone-based self-monitoring of diet and physical activity

Group B control arm

Participants use the smart-phone app to record their daily diet and physical activity, with no group sessions.

Group Type OTHER

Lifestyle App

Intervention Type BEHAVIORAL

A mobile app used to assist with lifestyle changes

Abbreviated Look AHEAD behavior lifestyle intervention

Intervention Type BEHAVIORAL

An abbreviated Look AHEAD behavior lifestyle intervention with smartphone-based self-monitoring of diet and physical activity

Interventions

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Lifestyle App

A mobile app used to assist with lifestyle changes

Intervention Type BEHAVIORAL

Look AHEAD behavior lifestyle intervention

A modified Look AHEAD behavior lifestyle intervention with smartphone-based self-monitoring of diet and physical activity

Intervention Type BEHAVIORAL

Abbreviated Look AHEAD behavior lifestyle intervention

An abbreviated Look AHEAD behavior lifestyle intervention with smartphone-based self-monitoring of diet and physical activity

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Community-dwelling
* Age 65 and older
* Men and women of all ethnic groups
* Self-reported of provider-diagnosed with Type 2 Diabetes (T2D) for at-least 6 months.
* Received basic diabetes self-management education
* Stable medication regimen and no medication changes are expected over the next 6 months.
* Overweight/obese (Body Mass Index (BMI) ≥25 kg/m2
* Able to read and write in English
* Own a smartphone
* At PI discretion, participant is willing/able to comply with the protocol requirements

Exclusion Criteria

* Unsafe to walk using Exercise Assessment and Screening for You (EASY) criteria or clinical judgement of the PI.
* History of severe psychiatric disorders or cognitive impairment which interferes with active participation in the study
* Residence of long-term care facility
* History of substance abuse in the past year
* Unwilling to be randomized in a Mobile Health (mHealth+) individual intervention group
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The Claude D. Pepper Older Americans Independence Centers

OTHER

Sponsor Role collaborator

National Institute on Aging (NIA)

NIH

Sponsor Role collaborator

The University of Texas Health Science Center at San Antonio

OTHER

Sponsor Role lead

Responsible Party

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Rozmin Jiwani

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Rozmin Jiwani, RN, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Texas Health at San Antonio

Locations

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The University of Texas Health Science Center at San Antonio

San Antonio, Texas, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Related Links

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Other Identifiers

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P30AG044271

Identifier Type: NIH

Identifier Source: secondary_id

View Link

HSC20190019H

Identifier Type: -

Identifier Source: org_study_id

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