Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
4 participants
INTERVENTIONAL
2026-07-01
2032-08-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
OTHER
NONE
Study Groups
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Controlled Dietary Study
Participants will consume the controlled diet for five days and be administered an intravenous (IV) load of glycolate. Participants will provide urine and blood samples both before the glycolate load to establish baseline levels and after the glycolate load to measure oxalate levels afterwards.
Controlled Diet
Participants will consume a controlled low oxalate diet for five days.
Glycolate Administration
Participants will come to the UAB Clinical Research Unit (CRU) and be administered a glycolate load via intravenous (IV) catheter.
Interventions
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Controlled Diet
Participants will consume a controlled low oxalate diet for five days.
Glycolate Administration
Participants will come to the UAB Clinical Research Unit (CRU) and be administered a glycolate load via intravenous (IV) catheter.
Eligibility Criteria
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Inclusion Criteria
* history of calcium oxalate stones
* heterozygous mutation of the AGXT gene, as evidenced by results from the Invitae Nephrolithiasis Panel
* willingness to comply with a controlled diet for five days
Exclusion Criteria
* individuals who are currently breast feeding
18 Years
ALL
No
Sponsors
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University of Alabama at Birmingham
OTHER
Responsible Party
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Kyle D. Wood
Principal Investigator
Principal Investigators
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Kyle Wood, MD
Role: PRINCIPAL_INVESTIGATOR
University of Alabama at Birmingham
Central Contacts
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Other Identifiers
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IRB-300005327
Identifier Type: -
Identifier Source: org_study_id
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