Assessment Psychological Distress for Cancer Heredity Test

NCT ID: NCT04428710

Last Updated: 2021-02-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

800 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-10-01

Study Completion Date

2021-12-31

Brief Summary

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The study of hereditary cancer related syndromes allows reducing the risk of suffering in cancer to patients and close relatives. The objective of this study will be to evaluate the prevelance of psychological morbidity in patients attended at cancer genetic counselling unit, and to determine the socio-demographic and clinical factors that influence it.

A descriptive cross-sectional study will be carried out. Patients attented at the cancer genetic counselling unit, who have criteria for conducting a genetic syndrome test related to hererditary cancer, will be consecutively evaluated.

To knowing the psychological morbidity it is relevant to providing care for these patients.

Detailed Description

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Nowadays several familial cancer syndromes that confer a high lifetime risk of cancer can be identified with genetic testing. The psychological impact of genetic testing and the rates of psychological distress in patients undergoing genetic testing vary between 6 to 65% depending on socio-demographic or clinical characteristics.

The effect of baseline distress on post-testing assessments tended to decrease or show little change over time, it may be important to target patients with high baseline distress for additional counseling or intervention both pre-testing and over time.The most robust predictor of future distress is baseline distress, additional factors were associated with cancer risk perception considering family history of cancer, patient's affected or unaffected with cancer, etc...

It is relevant to developing and providing care for these patients, it has been demonstrated that enhanced genetic counseling with clinical psychologist to facilitate decision-making process, managing family concerns promoting their communication with and involvement of family members, and attending their emotional distress, can be beneficial. Also, cancer genetic counseling may promote patient use of personal resources and enhance patient health literacy about their syndrome.

Conditions

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Cancer Psychological Distress Hereditary Diseases Genetic Counseling

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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patients admitted to cancer genetic counseling test

Participants were recruited from all consecutive patients referred to the Cancer Genetic Program at the Hospital Universitari i Politècnic la Fe.

assessment with psychometric questionnaire

Intervention Type OTHER

At the initial genetic consultation patients are informed about hereditary cancer risk and the genetic testing process. At the second genetic counseling appointment, after patients done tests, all participants were informed about the study purpose, and they signed the informed consent before the psychometric assessment. Those patients who agreed to participate, they were given the questionnaires to fill in. Also, background characteristics were reported including age, marital relationship, level of education, psychiatric antecedents.

The time for completion the self-report measures was about 10 minutes. The psychometric assessment was occurred prior to delivering the results of genetic testing.

Interventions

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assessment with psychometric questionnaire

At the initial genetic consultation patients are informed about hereditary cancer risk and the genetic testing process. At the second genetic counseling appointment, after patients done tests, all participants were informed about the study purpose, and they signed the informed consent before the psychometric assessment. Those patients who agreed to participate, they were given the questionnaires to fill in. Also, background characteristics were reported including age, marital relationship, level of education, psychiatric antecedents.

The time for completion the self-report measures was about 10 minutes. The psychometric assessment was occurred prior to delivering the results of genetic testing.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age between 18 and 80 years
* Factors presumed predictive for hereditary cáncer
* They agreed to participate in the research.

Exclusion Criteria

* Patients with cognitive impairment
* Patients with difficulties to read and understand Spanish language.
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Hospital Universitario La Fe

OTHER

Sponsor Role lead

Responsible Party

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Gemma Costa Requena

PhD Clinical psychologist

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Hospital Universitari i Politècnic La Fe

Valencia, , Spain

Site Status

Countries

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Spain

References

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Costa-Requena G, Garcia-Garijo M, Richart-Aznar P, Segura-Huerta A. Comparison of psychological distress for breast, ovarian and colorectal cancer predisposition in a Spanish sample at high risk of hereditary cancer. Eur J Cancer Prev. 2022 Sep 1;31(5):482-486. doi: 10.1097/CEJ.0000000000000734. Epub 2021 Dec 15.

Reference Type DERIVED
PMID: 36165038 (View on PubMed)

Costa-Requena G, Garcia-Garijo M, Richart-Aznar P, Segura-Huerta A. Psychiatric symptoms in a Spanish sample with hereditary cancer risk. J Community Genet. 2022 Jun;13(3):339-346. doi: 10.1007/s12687-022-00580-5. Epub 2022 Feb 8.

Reference Type DERIVED
PMID: 35133604 (View on PubMed)

Other Identifiers

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Cancer Genetic Counseling.PSI

Identifier Type: -

Identifier Source: org_study_id

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