Post-marketing Surveillance of EVRENZO® Tablets (Roxadustat) in Patients With Renal Anemia

NCT ID: NCT04408820

Last Updated: 2025-07-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

2104 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-06-01

Study Completion Date

2025-06-23

Brief Summary

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The purpose of this study is to assess the safety and efficacy, including the incidence of thromboembolism, in renal anemia patients treated with roxadustat (EVRENZO® Tablets) in actual clinical settings.

Detailed Description

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This is a post-marketing long-term specified drug use-result survey study required for products in Japan. In the survey, patient registration and data collection will be conducted using post-marketing survey data collection system, PostMaNet via the Internet.

Patients who are eligible for the survey will be registered within 14 days after the start of treatment with roxadustat (including the start day of treatment). For all registered patients (including discontinuations/dropouts), the investigator will enter the necessary information in the case report form (CRF) and send it immediately after the end of the specified observation period for each patient.

Conditions

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Renal Anemia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Roxadustat

Participants will receive oral dose of roxadustat.

Roxadustat

Intervention Type DRUG

Oral

Interventions

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Roxadustat

Oral

Intervention Type DRUG

Other Intervention Names

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ASP1517 Evrenzo

Eligibility Criteria

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Inclusion Criteria

* Renal anemia patients who are naïve to roxadustat.

Exclusion Criteria

* Not applicable
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Astellas Pharma Inc

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Astellas Pharma Inc.

Role: STUDY_DIRECTOR

Astellas Pharma Inc

Locations

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Site JP00023

Aichi, , Japan

Site Status

Site JP00005

Akita, , Japan

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Site JP00002

Aomori, , Japan

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Site JP00012

Chiba, , Japan

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Site JP00038

Ehime, , Japan

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Site JP00018

Fukui, , Japan

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Site JP00040

Fukuoka, , Japan

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Site JP00007

Fukushima, , Japan

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Site JP00021

Gifu, , Japan

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Site JP00010

Gunma, , Japan

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Site JP00034

Hiroshima, , Japan

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Site JP00001

Hokkaido, , Japan

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Site JP00028

Hyōgo, , Japan

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Site JP00008

Ibaraki, , Japan

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Site JP00017

Ishikawa, , Japan

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Site JP00037

Kagawa, , Japan

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Site JP00046

Kagoshima, , Japan

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Site JP00014

Kanagawa, , Japan

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Site JP00039

Kochi, , Japan

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Site JP00043

Kumamoto, , Japan

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Site JP00026

Kyoto, , Japan

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Site JP00024

Mie, , Japan

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Site JP00004

Miyagi, , Japan

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Site JP00045

Miyazaki, , Japan

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Site JP00020

Nagano, , Japan

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Site JP00042

Nagasaki, , Japan

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Site JP00029

Nara, , Japan

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Site JP00015

Niigata, , Japan

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Site JP00003

Numakunai, , Japan

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Site JP00033

Okayama, , Japan

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Site JP00047

Okinawa, , Japan

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Site JP00027

Osaka, , Japan

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Site JP00044

Ōita, , Japan

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Site JP00041

Saga, , Japan

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Site JP00011

Saitama, , Japan

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Site JP00025

Shiga, , Japan

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Site JP00032

Shimane, , Japan

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Site JP00022

Shizuoka, , Japan

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Site JP00009

Tochigi, , Japan

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Site JP00036

Tokushima, , Japan

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Site JP00013

Tokyo, , Japan

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Site JP00031

Tottori, , Japan

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Site JP00016

Toyama, , Japan

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Site JP00030

Wakayama, , Japan

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Site JP00006

Yamagata, , Japan

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Site JP00035

Yamaguchi, , Japan

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Site JP00019

Yamanashi, , Japan

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Countries

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Japan

References

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Tsuruya K, Sugamori H, Tanaka Y, Wakasugi N, Ito Y. Real-world safety and effectiveness of roxadustat in patients with anemia of chronic kidney disease: interim results from a post-marketing surveillance study in Japan. Expert Opin Pharmacother. 2025 Mar;26(4):503-517. doi: 10.1080/14656566.2025.2462181. Epub 2025 Feb 7.

Reference Type DERIVED
PMID: 39899733 (View on PubMed)

Other Identifiers

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1517-MA-3318

Identifier Type: -

Identifier Source: org_study_id

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