0.12% Chlorhexidine Oral Care for the Prevention of Non-ventilator Hospital-acquired Pneumonia
NCT ID: NCT04403971
Last Updated: 2021-12-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
103 participants
INTERVENTIONAL
2020-05-25
2020-12-31
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
SEQUENTIAL
PREVENTION
TRIPLE
Study Groups
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0.12% chlorhexidine
Participants will be randomized to Chlorhexidine solution group, applied twice a day by care givers.
0.12% Chlorhexidine Oral Liquid Product
The intervention group 1 received 10ml 0.12% chlorhexidine solution for oral rinse twice a day.
Listerine
Participants will be randomized to Listerine solution group, applied twice a day by care givers.
Listerine Oral Liquid Product
The intervention group 2 received 10ml Listerine solution for oral rinse twice a day.
Normal saline
Participants will be randomized to Normal saline group, applied twice a day by care givers.
Normal Saline Product
The control group received 10ml normal saline for oral rinse twice a day.
Interventions
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0.12% Chlorhexidine Oral Liquid Product
The intervention group 1 received 10ml 0.12% chlorhexidine solution for oral rinse twice a day.
Listerine Oral Liquid Product
The intervention group 2 received 10ml Listerine solution for oral rinse twice a day.
Normal Saline Product
The control group received 10ml normal saline for oral rinse twice a day.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
20 Years
100 Years
ALL
No
Sponsors
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National Cheng-Kung University Hospital
OTHER
Responsible Party
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Chen, Yen-Chin
Vice Head Nurse and Clinical Assistant Professor
Locations
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Yen-Chin Chen
Tainan City, , Taiwan
Countries
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References
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Sangmuang P, Lucksiri A, Katip W. Factors Associated with Mortality in Immunocompetent Patients with Hospital-acquired Pneumonia. J Glob Infect Dis. 2019 Jan-Mar;11(1):13-18. doi: 10.4103/jgid.jgid_33_18.
Giuliano KK, Baker D, Quinn B. The epidemiology of nonventilator hospital-acquired pneumonia in the United States. Am J Infect Control. 2018 Mar;46(3):322-327. doi: 10.1016/j.ajic.2017.09.005. Epub 2017 Oct 16.
Quinn B, Baker DL, Cohen S, Stewart JL, Lima CA, Parise C. Basic nursing care to prevent nonventilator hospital-acquired pneumonia. J Nurs Scholarsh. 2014 Jan;46(1):11-9. doi: 10.1111/jnu.12050. Epub 2013 Sep 30.
Chou CC, Shen CF, Chen SJ, Chen HM, Wang YC, Chang WS, Chang YT, Chen WY, Huang CY, Kuo CC, Li MC, Lin JF, Lin SP, Ting SW, Weng TC, Wu PS, Wu UI, Lin PC, Lee SS, Chen YS, Liu YC, Chuang YC, Yu CJ, Huang LM, Lin MC; Infectious Diseases Society of Taiwan;; Taiwan Society of Pulmonary and Critical Care Medicine,; Medical Foundation in Memory of Dr. Deh-Lin Cheng;; Foundation of Professor Wei-Chuan Hsieh for Infectious Diseases Research and Education;; CY Lee's Research Foundation for Pediatric Infectious Diseases and Vaccines,; 4th Guidelines Recommendations for Evidence-based Antimicrobial agents use in Taiwan (GREAT) working group. Recommendations and guidelines for the treatment of pneumonia in Taiwan. J Microbiol Immunol Infect. 2019 Feb;52(1):172-199. doi: 10.1016/j.jmii.2018.11.004. Epub 2018 Dec 6.
Zhang J, Ab Malik N, McGrath C, Lam O. The effect of antiseptic oral sprays on dental plaque and gingival inflammation: A systematic review and meta-analysis. Int J Dent Hyg. 2019 Feb;17(1):16-26. doi: 10.1111/idh.12331. Epub 2018 Feb 6.
Other Identifiers
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A-ER-108-309
Identifier Type: -
Identifier Source: org_study_id