Trial Outcomes & Findings for The Effect of Dapagliflozin on Platelet Function testinG Profiles in Diabetic PatiEnts. (NCT NCT04400760)

Last Updated: 2023-11-07

Results Overview

Platelet Reaction units at baseline and post-DAPA Tx treatment with dapagliflozin

Recruitment status

COMPLETED

Study phase

PHASE2/PHASE3

Target enrollment

40 participants

Primary outcome timeframe

Baseline (0 weeks) to Completion (2 weeks) after Dapagliflozin

Results posted on

2023-11-07

Participant milestones
Measure	DAPA Tx This arm will comprise the participants who are administered Dapagliflozin 10mg per oral once daily for 2 weeks. DAPA Tx: The intervention, dapagliflozin will be administered 10mg per oral daily for two weeks.
Overall Study STARTED	40
Overall Study COMPLETED	27
Overall Study NOT COMPLETED	13

Withdrawal data not reported

The Effect of Dapagliflozin on Platelet Function testinG Profiles in Diabetic PatiEnts.

Baseline characteristics by cohort
Measure	DAPA Tx n=27 Participants This arm will comprise the participants who are administered Dapagliflozin 10mg per oral once daily for 2 weeks. DAPA Tx: The intervention, dapagliflozin will be administered 10mg per oral daily for two weeks.
Age, Continuous	63.5 years STANDARD_DEVIATION 1 • n=5 Participants
Sex: Female, Male Female	12 Participants n=5 Participants
Sex: Female, Male Male	15 Participants n=5 Participants
Race (NIH/OMB) American Indian or Alaska Native	0 Participants n=5 Participants
Race (NIH/OMB) Asian	20 Participants n=5 Participants
Race (NIH/OMB) Native Hawaiian or Other Pacific Islander	0 Participants n=5 Participants
Race (NIH/OMB) Black or African American	4 Participants n=5 Participants
Race (NIH/OMB) White	0 Participants n=5 Participants
Race (NIH/OMB) More than one race	3 Participants n=5 Participants
Race (NIH/OMB) Unknown or Not Reported	0 Participants n=5 Participants
PRU	160.93 PRU STANDARD_DEVIATION 1 • n=5 Participants

Timeframe: Baseline (0 weeks) to Completion (2 weeks) after Dapagliflozin

Platelet Reaction units at baseline and post-DAPA Tx treatment with dapagliflozin

Outcome measures
Measure	DAPA Tx n=27 Participants This arm will comprise the participants who are administered Dapagliflozin 10mg per oral once daily for 2 weeks. DAPA Tx: The intervention, dapagliflozin will be administered 10mg per oral daily for two weeks.
Platelet Reactions Units Pre-DAPA Tx and Post-DAPA Tx	160.93 PRU Interval 129.28 to 192.57

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Adverse event data not reported

Adverse event data not reported

The University of the West Indies, St. Augustine

Phone: 18687537686