Compare the Pharmacokinetics and Safety of CKD-391

NCT ID: NCT04354987

Last Updated: 2020-04-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

44 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-10-30

Study Completion Date

2020-01-09

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

phase I clinical trial to compare the pharmacokinetics and safety of CKD-391 with co-administration of D090 and D337 in healthy adult volunteers

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Hyperlipidemias

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Group A

R+R+T+T Period 1 : R Period 2 : R Period 3 : T Period 4 : T

Group Type EXPERIMENTAL

CKD-391 10/10mg

Intervention Type DRUG

Drug T: CKD-391 10/10mg(Other Name: Test Drug)

D090, D337

Intervention Type DRUG

D090 and D337 co-administration(Other Name: Reference drug)

Group B

R+T+R+T Period 1 : R Period 2 : T Period 3 : R Period 4 : T

Group Type EXPERIMENTAL

CKD-391 10/10mg

Intervention Type DRUG

Drug T: CKD-391 10/10mg(Other Name: Test Drug)

D090, D337

Intervention Type DRUG

D090 and D337 co-administration(Other Name: Reference drug)

Group C

T+R+T+R Period 1 : T Period 2 : R Period 3 : T Period 4 : R

Group Type EXPERIMENTAL

CKD-391 10/10mg

Intervention Type DRUG

Drug T: CKD-391 10/10mg(Other Name: Test Drug)

D090, D337

Intervention Type DRUG

D090 and D337 co-administration(Other Name: Reference drug)

Group D

T+T+R+R Period 1 : T Period 2 : T Period 3 : R Period 4 : R

Group Type EXPERIMENTAL

CKD-391 10/10mg

Intervention Type DRUG

Drug T: CKD-391 10/10mg(Other Name: Test Drug)

D090, D337

Intervention Type DRUG

D090 and D337 co-administration(Other Name: Reference drug)

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

CKD-391 10/10mg

Drug T: CKD-391 10/10mg(Other Name: Test Drug)

Intervention Type DRUG

D090, D337

D090 and D337 co-administration(Other Name: Reference drug)

Intervention Type DRUG

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Test Drug (T) Reference Drug (R)

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

1. Between 19 aged and 45 aged in healthy male adult
2. Subjects in good health as determined by physical exams and medical examinations. No congenital or chronic diseases and no abnormal signs determined by medical examinations.
3. Not abnormal or not clinically significant lab values.
4. Subjects who signed informed consent form with good understandings after explanations by investigators.

Exclusion Criteria

1. No history or presence of clinically significant diseases.
2. Subjects showing adverse reaction to investigational product
3. Genetic problems in galactose intolerance, Lapp lactose deficiency, or glucose-galactose malabsorption.
4. History of myopathy
5. unable to stop drinking and smoking during clinical trials
6. Subjects who donated whole blood within 60 days or donated component blood within 30 days or received blood transfusion within 30 days
7. History of drug abuse
8. Disagree to contraception
9. Subjects who are in any conditions impossible participating in the clinical trials
Minimum Eligible Age

19 Years

Maximum Eligible Age

45 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Seoul National University Bundang Hospital

OTHER

Sponsor Role collaborator

Chong Kun Dang Pharmaceutical

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Jae-Yong Chung

Gyeonggi-do, Seongnam-si, South Korea

Site Status

Countries

Review the countries where the study has at least one active or historical site.

South Korea

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

152BE18037

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.