Effect of Lidocaine and Adrenaline Soaked Gauze Versus Normal Saline Soaked at Skin Graft Donor Site of Thigh
NCT ID: NCT04344483
Last Updated: 2020-11-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
60 participants
INTERVENTIONAL
2019-12-10
2020-06-10
Brief Summary
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Haemostatic effect, epithelization and post operative pain will be assessed on follow up.
Detailed Description
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Group A will be receiving 2% lidocaine and 1:100,000 adrenaline soaked gauze while group B will be given only normal saline soaked gauze at donor-site for ten minutes.
The primary end point of study is intraoperative bleeding. The secondary end points of study include no. of dressings required in first 24 hours after surgery, donor site epithelization at 14th post-operative day, post-operative pain in first 24 hours after surgery along with systemic analgesia requirement after surgery.
Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
SINGLE
Study Groups
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Group A ( Lidocaine + Adrenaline)
Group A patients will receive 2% Lidocaine and 1:100,000 adrenaline soaked gauze over skin graft donor site of thigh per operatively for 10 minutes. After 10 minutes this dressing will be removed and sufratul dressing will be applied over donor site.
2% Lidocaine and 1:100,000 Adrenaline
Topical application of 2% Lidocaine and 1:100,000 Adrenaline in the form of dressing will be applied over skin graft donor site of thigh for 10 minutes.
Group B ( Normal Saline)
Group B patients will receive normal saline soaked gauze over skin graft donor site of thigh intraoperatively for 10 minutes. After 10 minutes this dressing will be removed and sufratul dressing will be applied over donor site
Normal saline
Topical application of Normal saline will be applied over skin graft donor site of thigh as a control group.
Interventions
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2% Lidocaine and 1:100,000 Adrenaline
Topical application of 2% Lidocaine and 1:100,000 Adrenaline in the form of dressing will be applied over skin graft donor site of thigh for 10 minutes.
Normal saline
Topical application of Normal saline will be applied over skin graft donor site of thigh as a control group.
Eligibility Criteria
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Inclusion Criteria
* Multiple donor-sites
Exclusion Criteria
* Concomitant injuries
* Donor site other than thigh
* Previously harvested donor-site
* Patients on antiplatelet medications
15 Years
ALL
Yes
Sponsors
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Dow University of Health Sciences
OTHER
Responsible Party
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Zaara Zahid
Principle investigator
Locations
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Zaara Zahid
Karachi, Sindh, Pakistan
Countries
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References
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Gacto P, Miralles F, Pereyra JJ, Perez A, Martinez E. Haemostatic effects of adrenaline-lidocaine subcutaneous infiltration at donor sites. Burns. 2009 May;35(3):343-7. doi: 10.1016/j.burns.2008.06.019. Epub 2008 Oct 23.
Related Links
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Gacto P, Miralles F, Pereyra J, Perez A, Martinez E. Haemostatic effects of adrenaline-lidocaine subcutaneous infiltration at donor sites. Burns. 2009;35(3):343-7.
Other Identifiers
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1506
Identifier Type: -
Identifier Source: org_study_id