Reducing Weight and Elevated Stress Levels Using Educational and Behavioral Tools

NCT ID: NCT04335799

Last Updated: 2025-12-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

341 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-10-12

Study Completion Date

2027-03-31

Brief Summary

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The purpose of this protocol is to test the effects on weight of an evidence-based behavioral weight loss program enhanced with culturally targeted stress management strategies compared to the evidence-based weight loss program alone among adult black females with obesity and elevated stress levels. Participants will be randomized to receive either a behavioral weight loss intervention with a focus on stress management or the weight loss intervention alone for 26 sessions.

Detailed Description

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Conditions

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Obesity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Weight Loss Plus Stress Management

Diabetes Prevention Program Intensive Lifestyle Intervention augmented with stress management training

Group Type EXPERIMENTAL

Diabetes Prevention Program Intensive Lifestyle Intervention plus stress management training

Intervention Type BEHAVIORAL

12-month evidence based weight loss intervention with additional training on stress management strategies

Weight Loss Only

Diabetes Prevention Program Intensive Lifestyle Intervention plus general women's health topics

Group Type ACTIVE_COMPARATOR

Diabetes Prevention Program Intensive Lifestyle Intervention plus general women's health topics

Intervention Type BEHAVIORAL

12-month evidence based weight loss intervention with an attention control of general women's health topics

Interventions

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Diabetes Prevention Program Intensive Lifestyle Intervention plus stress management training

12-month evidence based weight loss intervention with additional training on stress management strategies

Intervention Type BEHAVIORAL

Diabetes Prevention Program Intensive Lifestyle Intervention plus general women's health topics

12-month evidence based weight loss intervention with an attention control of general women's health topics

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* BMI of at least 30 kg/m\^2
* elevated stress levels based on perceived stress scale score
* self-identified as black race

Exclusion Criteria

* pregnant or are planning to become pregnant in the next year
* known major medical or psychological condition known to influence body weight loss (e.g., medicated or poorly controlled diabetes (fasting blood glucose \> 126 mg/dL), cardiovascular event in the preceding 12 months, history of gastric bypass surgery, bariatric surgery, or eating disorder)
* history of psychiatric hospitalization in past 2 years
* history of substance abuse or eating disorder
* any condition for which a medical professional has suggested diet modification, physical activity, and/or weight reduction would be contraindicated.
* currently taking medications for weight loss
Minimum Eligible Age

21 Years

Maximum Eligible Age

75 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

Sponsor Role collaborator

H. Lee Moffitt Cancer Center and Research Institute

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Tiffany L Carson, PhD

Role: PRINCIPAL_INVESTIGATOR

Moffitt Cancer Center

Locations

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Moffitt Cancer Center

Tampa, Florida, United States

Site Status

Countries

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United States

References

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Buro AW, Baskin M, Miller D, Ward T, West DS, Gore LR, Gwede CK, Epel E, Carson TL. Rationale and study protocol for a randomized controlled trial to determine the effectiveness of a culturally relevant, stress management enhanced behavioral weight loss intervention on weight loss outcomes of black women. BMC Public Health. 2022 Jan 28;22(1):193. doi: 10.1186/s12889-022-12519-z.

Reference Type DERIVED
PMID: 35090433 (View on PubMed)

Related Links

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Other Identifiers

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R01DK125367

Identifier Type: NIH

Identifier Source: secondary_id

View Link

MCC-21236

Identifier Type: -

Identifier Source: org_study_id

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