Motion Syros: A Study to Investigate the Efficacy of Tradipitant in Subjects Affected by Motion Sickness
NCT ID: NCT04327661
Last Updated: 2024-12-11
Study Results
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View full resultsBasic Information
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COMPLETED
PHASE3
366 participants
INTERVENTIONAL
2021-11-15
2023-04-12
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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Tradipitant High Dose
Tradipitant
Oral Capsule
Tradipitant Low Dose
Tradipitant
Oral Capsule
Placebo
Placebo
Oral Capsule
Interventions
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Tradipitant
Oral Capsule
Placebo
Oral Capsule
Eligibility Criteria
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Inclusion Criteria
* Age 18-75
Exclusion Criteria
* BMI\>40
* History of intolerance and/or hypersensitivity to Neurokinin-1 Receptor antagonists
18 Years
75 Years
ALL
No
Sponsors
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Vanda Pharmaceuticals
INDUSTRY
Responsible Party
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Locations
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Pacific Research Network, LLC
San Diego, California, United States
Santa Monica Clinical Trials
Santa Monica, California, United States
Gulfcoast Psychiatric Associates
Fort Myers, Florida, United States
Harmony Clinical Research
North Miami Beach, Florida, United States
Avita Clinical Research
Tampa, Florida, United States
Beacon Clinical Research
Quincy, Massachusetts, United States
Manhattan Medical Research
New York, New York, United States
Countries
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References
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Polymeropoulos VM, Kiely L, Bushman ML, Sutherland EB, Goldberg AR, Pham AX, Miller CR, Mourad R, Davis TR, Pham NV, Morgan DB, Giles AK, Xiao C, Polymeropoulos CM, Birznieks G, Polymeropoulos MH. Motion Syros: tradipitant effective in the treatment of motion sickness; a multicenter, randomized, double-blind, placebo-controlled study. Front Neurol. 2025 Mar 4;16:1550670. doi: 10.3389/fneur.2025.1550670. eCollection 2025.
Provided Documents
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Document Type: Study Protocol and Statistical Analysis Plan
Other Identifiers
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VP-VLY-686-3401
Identifier Type: -
Identifier Source: org_study_id