Retinol-binding Protein 4 (RBP4) Metabolizm in Type 2 Diabetes Progression and Associated Cardiovascular Complications
NCT ID: NCT04325126
Last Updated: 2022-12-23
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
500 participants
OBSERVATIONAL
2020-04-01
2023-01-31
Brief Summary
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Detailed Description
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Blood pressure, WC, hip circumference (HC), body weight and body height were measured by a trained physician. The participants enrolled in the study provided written informed consent.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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RBP4 in diabetes
RBP4 in diagnosed diabetes.
Exposure factors
Exposure factors，such as diet，exercise，environment
RBP4 in pre-diabetes (pre-DM)
RBP4 in pre-diabetes (pre-DM).
Exposure factors
Exposure factors，such as diet，exercise，environment
RBP4 in DM-CVD
RBP4 in diabetic cardiovascular disease.
Exposure factors
Exposure factors，such as diet，exercise，environment
RBP4 in CVD
RBP4 in single coronary artery disease.
Exposure factors
Exposure factors，such as diet，exercise，environment
RBP4 in NC
RBP4 in healthy controls.
Exposure factors
Exposure factors，such as diet，exercise，environment
Interventions
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Exposure factors
Exposure factors，such as diet，exercise，environment
Eligibility Criteria
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Inclusion Criteria
* Fasting plasma glucose (FPG)≥7.0 mmol/l;
* 2 h plasma glucose (2hPG) ≥11.1 mmol/l;
* glycated hemoglobin (HbA1c) level ≥6.5%;
* random plasma glucose ≥11.1 mmol/l plus symptoms of hyperglycemia;
* T2DM diagnosed previously.
Pre-DM was defned as follows:
* FPG ≥5.6-6.9 mmol/l
* 2hPG 7.8-11.0 mmol/l
* HbA1c 5.7-6.4%.
Exclusion Criteria
* liver or kidney disorders.
18 Years
70 Years
ALL
Yes
Sponsors
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First Affiliated Hospital Xi'an Jiaotong University
OTHER
Responsible Party
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Principal Investigators
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Jing Sui, doctor
Role: STUDY_DIRECTOR
First Affiliated Hospital Xi'an Jiaotong University
Locations
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The First Affiliated Hospital of Xi'an Jiaotong University
Xi'an, Shaanxi, China
Countries
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Central Contacts
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Facility Contacts
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Jing Sui, doctor
Role: primary
Other Identifiers
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XJTU 2020 G-66
Identifier Type: -
Identifier Source: org_study_id