Trial Outcomes & Findings for PEERS Using Peer Mentors to Deliver Depression Care (NCT NCT04319094)
NCT ID: NCT04319094
Last Updated: 2024-11-20
Results Overview
Depression will be assessed with the Patient Health Questionnaire (PHQ)-9. The PHQ-9 score is summed. There are 9 items in the questionnaire and scores range from 0 to 27. A score of 5 indicates mild depressive symptoms, 10 - 14 indicates moderate depression, 15-19 indicates moderately severe depression, 20-27 indicates severe depression.
Recruitment status
COMPLETED
Study phase
NA
Target enrollment
149 participants
Primary outcome timeframe
Baseline, post-intervention (8-week), 3 months after intervention, 6 months after intervention, 9 months after intervention, 12 months after intervention
Results posted on
2024-11-20
Participant Flow
Participant milestones
| Measure |
PEERS
Peer mentors who have experience of depression are trained and supervised to deliver depression care. Peers will meet with depressed older adults for 8 weekly meeting lasting approximately 45 -60 minutes. Peer mentors will provide social support defined as emotional, informational and appraisal support that includes coping strategies. Peers will be supervised by a mental health professional.
PEERS: Peer mentors deliver depression care that include social support and coping skills, focused on goal setting and small behavioral changes.
|
Social Interaction
A study staff member will provide eight weekly social interaction phone calls to the depressed older adult.
Social interaction: Study staff will provide a social interaction phone calls to the participants randomized to this condition.
|
|---|---|---|
|
Baseline
STARTED
|
75
|
74
|
|
Baseline
COMPLETED
|
69
|
65
|
|
Baseline
NOT COMPLETED
|
6
|
9
|
|
Post-Intervention
STARTED
|
69
|
65
|
|
Post-Intervention
COMPLETED
|
56
|
52
|
|
Post-Intervention
NOT COMPLETED
|
13
|
13
|
|
3-month
STARTED
|
57
|
55
|
|
3-month
COMPLETED
|
45
|
43
|
|
3-month
NOT COMPLETED
|
12
|
12
|
|
6-month
STARTED
|
54
|
50
|
|
6-month
COMPLETED
|
39
|
37
|
|
6-month
NOT COMPLETED
|
15
|
13
|
|
9-month
STARTED
|
53
|
46
|
|
9-month
COMPLETED
|
37
|
36
|
|
9-month
NOT COMPLETED
|
16
|
10
|
|
12-month
STARTED
|
45
|
41
|
|
12-month
COMPLETED
|
34
|
33
|
|
12-month
NOT COMPLETED
|
11
|
8
|
Reasons for withdrawal
| Measure |
PEERS
Peer mentors who have experience of depression are trained and supervised to deliver depression care. Peers will meet with depressed older adults for 8 weekly meeting lasting approximately 45 -60 minutes. Peer mentors will provide social support defined as emotional, informational and appraisal support that includes coping strategies. Peers will be supervised by a mental health professional.
PEERS: Peer mentors deliver depression care that include social support and coping skills, focused on goal setting and small behavioral changes.
|
Social Interaction
A study staff member will provide eight weekly social interaction phone calls to the depressed older adult.
Social interaction: Study staff will provide a social interaction phone calls to the participants randomized to this condition.
|
|---|---|---|
|
Baseline
Lost to Follow-up
|
4
|
5
|
|
Baseline
Protocol Violation
|
0
|
3
|
|
Baseline
Withdrawal by Subject
|
2
|
1
|
|
Post-Intervention
Death
|
0
|
1
|
|
Post-Intervention
Lost to Follow-up
|
4
|
4
|
|
Post-Intervention
Withdrawal by Subject
|
8
|
5
|
|
Post-Intervention
Incomplete Data Collection
|
1
|
3
|
|
3-month
Death
|
1
|
0
|
|
3-month
Lost to Follow-up
|
2
|
2
|
|
3-month
Withdrawal by Subject
|
0
|
3
|
|
3-month
Incomplete data collection
|
9
|
7
|
|
6-month
Lost to Follow-up
|
1
|
1
|
|
6-month
Withdrawal by Subject
|
0
|
3
|
|
6-month
Incomplete data collection
|
14
|
9
|
|
9-month
Lost to Follow-up
|
8
|
4
|
|
9-month
Withdrawal by Subject
|
0
|
1
|
|
9-month
Incomplete data collection
|
8
|
5
|
|
12-month
Lost to Follow-up
|
11
|
8
|
Baseline Characteristics
PEERS Using Peer Mentors to Deliver Depression Care
Baseline characteristics by cohort
| Measure |
PEERS
n=69 Participants
Peer mentors who have experience of depression are trained and supervised to deliver depression care. Peers will meet with depressed older adults for 8 weekly meeting lasting approximately 45 -60 minutes. Peer mentors will provide social support defined as emotional, informational and appraisal support that includes coping strategies. Peers will be supervised by a mental health professional.
PEERS: Peer mentors deliver depression care that include social support and coping skills, focused on goal setting and small behavioral changes.
|
Social Interaction
n=65 Participants
A study staff member will provide eight weekly social interaction phone calls to the depressed older adult.
Social interaction: Study staff will provide a social interaction phone calls to the participants randomized to this condition.
|
Total
n=134 Participants
Total of all reporting groups
|
|---|---|---|---|
|
Age, Continuous
|
69.0 Years
n=5 Participants
|
70.0 Years
n=7 Participants
|
69.5 Years
n=5 Participants
|
|
Sex: Female, Male
Female
|
58 Participants
n=5 Participants
|
55 Participants
n=7 Participants
|
113 Participants
n=5 Participants
|
|
Sex: Female, Male
Male
|
11 Participants
n=5 Participants
|
10 Participants
n=7 Participants
|
21 Participants
n=5 Participants
|
|
Ethnicity (NIH/OMB)
Hispanic or Latino
|
3 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
3 Participants
n=5 Participants
|
|
Ethnicity (NIH/OMB)
Not Hispanic or Latino
|
66 Participants
n=5 Participants
|
65 Participants
n=7 Participants
|
131 Participants
n=5 Participants
|
|
Ethnicity (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
American Indian or Alaska Native
|
1 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
1 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Asian
|
0 Participants
n=5 Participants
|
1 Participants
n=7 Participants
|
1 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Black or African American
|
35 Participants
n=5 Participants
|
35 Participants
n=7 Participants
|
70 Participants
n=5 Participants
|
|
Race (NIH/OMB)
White
|
27 Participants
n=5 Participants
|
28 Participants
n=7 Participants
|
55 Participants
n=5 Participants
|
|
Race (NIH/OMB)
More than one race
|
5 Participants
n=5 Participants
|
1 Participants
n=7 Participants
|
6 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Unknown or Not Reported
|
1 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
1 Participants
n=5 Participants
|
|
Region of Enrollment
United States
|
69 participants
n=5 Participants
|
65 participants
n=7 Participants
|
134 participants
n=5 Participants
|
|
Patient Health Questionnaire-9
|
10.81 units on a scale
STANDARD_DEVIATION 4.88 • n=5 Participants
|
10.4 units on a scale
STANDARD_DEVIATION 4.7 • n=7 Participants
|
10.6 units on a scale
STANDARD_DEVIATION 4.78 • n=5 Participants
|
PRIMARY outcome
Timeframe: Baseline, post-intervention (8-week), 3 months after intervention, 6 months after intervention, 9 months after intervention, 12 months after interventionPopulation: All participants with at least one assessment completed
Depression will be assessed with the Patient Health Questionnaire (PHQ)-9. The PHQ-9 score is summed. There are 9 items in the questionnaire and scores range from 0 to 27. A score of 5 indicates mild depressive symptoms, 10 - 14 indicates moderate depression, 15-19 indicates moderately severe depression, 20-27 indicates severe depression.
Outcome measures
| Measure |
PEERS
n=69 Participants
Peer mentors who have experience of depression are trained and supervised to deliver depression care. Peers will meet with depressed older adults for 8 weekly meeting lasting approximately 45 minutes. Peer mentors will provide social support defined as emotional, informational and appraisal support that includes coping strategies. Peers will be supervised by a mental health professional.
PEERS: Peer mentors deliver depression care that include social support and coping skills, focused on goal setting and small behavioral changes.
|
Social Interaction
n=65 Participants
A study staff member will provide eight weekly social interaction visits and phone calls to the depressed older adult.
Social interaction: Study staff will provide a combination of 8 social interaction visits and phone calls to the participants randomized to this condition.
|
|---|---|---|
|
Patient Health Questionnaire-9
Post-intervention
|
6.66 score on a scale
Standard Deviation 4.51
|
7.33 score on a scale
Standard Deviation 4.28
|
|
Patient Health Questionnaire-9
3 Months
|
7.89 score on a scale
Standard Deviation 4.91
|
7.84 score on a scale
Standard Deviation 4.73
|
|
Patient Health Questionnaire-9
6 Months
|
7.95 score on a scale
Standard Deviation 4.81
|
8.03 score on a scale
Standard Deviation 5.35
|
|
Patient Health Questionnaire-9
9 Months
|
8.77 score on a scale
Standard Deviation 5.57
|
7.14 score on a scale
Standard Deviation 4.57
|
|
Patient Health Questionnaire-9
12 Months
|
8.09 score on a scale
Standard Deviation 5.05
|
8.42 score on a scale
Standard Deviation 5.01
|
SECONDARY outcome
Timeframe: Baseline, post-intervention (8-week), 3 months after intervention , 6 months after intervention, 9 months after intervention, 12 months interventionPopulation: All participants with at least one assessment completed
The RAND 36-Item Health Survey is a set of generic, coherent, and easily administered quality-of-life measures. Each item is scored on a 0 to 100 range. Higher scores indicate better functioning.The physical functioning subscale was calculated using the average of 10 of the 36 items (item 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
Outcome measures
| Measure |
PEERS
n=69 Participants
Peer mentors who have experience of depression are trained and supervised to deliver depression care. Peers will meet with depressed older adults for 8 weekly meeting lasting approximately 45 minutes. Peer mentors will provide social support defined as emotional, informational and appraisal support that includes coping strategies. Peers will be supervised by a mental health professional.
PEERS: Peer mentors deliver depression care that include social support and coping skills, focused on goal setting and small behavioral changes.
|
Social Interaction
n=65 Participants
A study staff member will provide eight weekly social interaction visits and phone calls to the depressed older adult.
Social interaction: Study staff will provide a combination of 8 social interaction visits and phone calls to the participants randomized to this condition.
|
|---|---|---|
|
Rand Health Survey Short Form 36 - Physical Functioning
Post-Intervention
|
47.64 score on a scale
Standard Deviation 28.82
|
50 score on a scale
Standard Deviation 30.07
|
|
Rand Health Survey Short Form 36 - Physical Functioning
3 Month
|
50.12 score on a scale
Standard Deviation 29.02
|
50.88 score on a scale
Standard Deviation 30.57
|
|
Rand Health Survey Short Form 36 - Physical Functioning
6 Month
|
43.48 score on a scale
Standard Deviation 27.34
|
49.69 score on a scale
Standard Deviation 29.13
|
|
Rand Health Survey Short Form 36 - Physical Functioning
9 Month
|
46.06 score on a scale
Standard Deviation 30.36
|
50.3 score on a scale
Standard Deviation 30.72
|
|
Rand Health Survey Short Form 36 - Physical Functioning
12 Month
|
49.62 score on a scale
Standard Deviation 26.09
|
44.46 score on a scale
Standard Deviation 29.04
|
SECONDARY outcome
Timeframe: Baseline, post-intervention (8-week), 3 months after intervention , 6 months after intervention, 9 months after intervention, 12 months interventionPopulation: All participants with at least one assessment completed
The RAND 36-Item Health Survey is a set of generic, coherent, and easily administered quality-of-life measures. Each item is scored on a 0 to 100 range. Higher scores indicate better functioning. The social functioning subscale was calculated using the average of 2 of the 36 items (item 20, 32)
Outcome measures
| Measure |
PEERS
n=69 Participants
Peer mentors who have experience of depression are trained and supervised to deliver depression care. Peers will meet with depressed older adults for 8 weekly meeting lasting approximately 45 minutes. Peer mentors will provide social support defined as emotional, informational and appraisal support that includes coping strategies. Peers will be supervised by a mental health professional.
PEERS: Peer mentors deliver depression care that include social support and coping skills, focused on goal setting and small behavioral changes.
|
Social Interaction
n=65 Participants
A study staff member will provide eight weekly social interaction visits and phone calls to the depressed older adult.
Social interaction: Study staff will provide a combination of 8 social interaction visits and phone calls to the participants randomized to this condition.
|
|---|---|---|
|
Rand Health Survey Short Form 36 Item - Social Functioning
Post-intervention
|
60.29 score on a scale
Standard Deviation 30.18
|
59.56 score on a scale
Standard Deviation 25.32
|
|
Rand Health Survey Short Form 36 Item - Social Functioning
3 Month
|
64.29 score on a scale
Standard Deviation 32.26
|
66.88 score on a scale
Standard Deviation 26.18
|
|
Rand Health Survey Short Form 36 Item - Social Functioning
6 Month
|
59.47 score on a scale
Standard Deviation 25.59
|
63.71 score on a scale
Standard Deviation 28.75
|
|
Rand Health Survey Short Form 36 Item - Social Functioning
9 Month
|
38.75 score on a scale
Standard Deviation 28.58
|
60.61 score on a scale
Standard Deviation 32.79
|
|
Rand Health Survey Short Form 36 Item - Social Functioning
12 Month
|
5.73 score on a scale
Standard Deviation 61.54
|
53.88 score on a scale
Standard Deviation 28.76
|
SECONDARY outcome
Timeframe: Baseline, post-intervention (8-week), 3 months after intervention , 6 months after intervention, 9 months after intervention, 12 months interventionPopulation: All participants with at least one assessment completed
The RAND 36-Item Health Survey is a set of generic, coherent, and easily administered quality-of-life measures. Each item is scored on a 0 to 100 range. Higher scores indicate better functioning. The emotional functioning subscale was calculated using the average of 3 of the 36 items (item 17, 18, 19)
Outcome measures
| Measure |
PEERS
n=69 Participants
Peer mentors who have experience of depression are trained and supervised to deliver depression care. Peers will meet with depressed older adults for 8 weekly meeting lasting approximately 45 minutes. Peer mentors will provide social support defined as emotional, informational and appraisal support that includes coping strategies. Peers will be supervised by a mental health professional.
PEERS: Peer mentors deliver depression care that include social support and coping skills, focused on goal setting and small behavioral changes.
|
Social Interaction
n=65 Participants
A study staff member will provide eight weekly social interaction visits and phone calls to the depressed older adult.
Social interaction: Study staff will provide a combination of 8 social interaction visits and phone calls to the participants randomized to this condition.
|
|---|---|---|
|
Rand Health Survey Short Form 36 Item - Emotional Functioning
12 Month
|
51.28 score on a scale
Standard Deviation 41.34
|
44.83 score on a scale
Standard Deviation 41.09
|
|
Rand Health Survey Short Form 36 Item - Emotional Functioning
Post-intervention
|
44.44 score on a scale
Standard Deviation 42.95
|
52.94 score on a scale
Standard Deviation 44.81
|
|
Rand Health Survey Short Form 36 Item - Emotional Functioning
3 Month
|
49.21 score on a scale
Standard Deviation 41.8
|
61.67 score on a scale
Standard Deviation 43.72
|
|
Rand Health Survey Short Form 36 Item - Emotional Functioning
6 Month
|
48.96 score on a scale
Standard Deviation 43.16
|
57.58 score on a scale
Standard Deviation 40.2
|
|
Rand Health Survey Short Form 36 Item - Emotional Functioning
9 month
|
49.49 score on a scale
Standard Deviation 44.19
|
52.53 score on a scale
Standard Deviation 38.22
|
SECONDARY outcome
Timeframe: Baseline, post-intervention (8-week), 3 months after intervention, 6 months after intervention, 9 months after intervention, 12 months after interventionPopulation: All participants with at least one assessment completed
Health service use is measured with the Cornell Service Index, a questionnaire that includes both clinical and informal community-based health services and has been used in depression care studies among older adults. The index asks whether an individual has used a list of services in the 4 months prior, what type of provider was seen, the site of the service, and reasons for service use. Numbers reported indicate the number of participants who reported hospital and emergency service use at specified timepoints.
Outcome measures
| Measure |
PEERS
n=69 Participants
Peer mentors who have experience of depression are trained and supervised to deliver depression care. Peers will meet with depressed older adults for 8 weekly meeting lasting approximately 45 minutes. Peer mentors will provide social support defined as emotional, informational and appraisal support that includes coping strategies. Peers will be supervised by a mental health professional.
PEERS: Peer mentors deliver depression care that include social support and coping skills, focused on goal setting and small behavioral changes.
|
Social Interaction
n=65 Participants
A study staff member will provide eight weekly social interaction visits and phone calls to the depressed older adult.
Social interaction: Study staff will provide a combination of 8 social interaction visits and phone calls to the participants randomized to this condition.
|
|---|---|---|
|
Cornell Health Service Index - ER Service Use
9 Month
|
13 Participants
|
9 Participants
|
|
Cornell Health Service Index - ER Service Use
12 Month
|
4 Participants
|
9 Participants
|
|
Cornell Health Service Index - ER Service Use
Post-intervention
|
5 Participants
|
8 Participants
|
|
Cornell Health Service Index - ER Service Use
3 Month
|
12 Participants
|
2 Participants
|
|
Cornell Health Service Index - ER Service Use
6 Month
|
7 Participants
|
7 Participants
|
SECONDARY outcome
Timeframe: Intervention 1-8 weeksPopulation: All participants with at least one assessment completed
Engagement (adherence) was measured by percentage of attendance of meetings as reported by the peer mentors, with a threshold of 80% of meetings attended.
Outcome measures
| Measure |
PEERS
n=69 Participants
Peer mentors who have experience of depression are trained and supervised to deliver depression care. Peers will meet with depressed older adults for 8 weekly meeting lasting approximately 45 minutes. Peer mentors will provide social support defined as emotional, informational and appraisal support that includes coping strategies. Peers will be supervised by a mental health professional.
PEERS: Peer mentors deliver depression care that include social support and coping skills, focused on goal setting and small behavioral changes.
|
Social Interaction
n=65 Participants
A study staff member will provide eight weekly social interaction visits and phone calls to the depressed older adult.
Social interaction: Study staff will provide a combination of 8 social interaction visits and phone calls to the participants randomized to this condition.
|
|---|---|---|
|
Engagement - Adherence
Week 1
|
67 Participants
|
62 Participants
|
|
Engagement - Adherence
Week 2
|
64 Participants
|
61 Participants
|
|
Engagement - Adherence
Week 3
|
61 Participants
|
60 Participants
|
|
Engagement - Adherence
Week 4
|
61 Participants
|
59 Participants
|
|
Engagement - Adherence
Week 5
|
60 Participants
|
58 Participants
|
|
Engagement - Adherence
Week 6
|
59 Participants
|
56 Participants
|
|
Engagement - Adherence
Week 7
|
57 Participants
|
56 Participants
|
|
Engagement - Adherence
Week 8
|
57 Participants
|
56 Participants
|
SECONDARY outcome
Timeframe: Intervention weeks 1-8Population: All participants in the PEERS intervention with at least one assessment completed
Working alliance was measured on a weekly basis only in the intervention arm with the Working Alliance Inventory-SF. The survey has 12 items with subscales that measure affective bond, and agreement on tasks and goals and are scored using a Likert scale. The goal subscore was calculated by summing items 1, 6, 8, and 11. The subscale ranges from scores of 4-28, with higher scores indicating better agreement on goals.
Outcome measures
| Measure |
PEERS
n=69 Participants
Peer mentors who have experience of depression are trained and supervised to deliver depression care. Peers will meet with depressed older adults for 8 weekly meeting lasting approximately 45 minutes. Peer mentors will provide social support defined as emotional, informational and appraisal support that includes coping strategies. Peers will be supervised by a mental health professional.
PEERS: Peer mentors deliver depression care that include social support and coping skills, focused on goal setting and small behavioral changes.
|
Social Interaction
A study staff member will provide eight weekly social interaction visits and phone calls to the depressed older adult.
Social interaction: Study staff will provide a combination of 8 social interaction visits and phone calls to the participants randomized to this condition.
|
|---|---|---|
|
Working Alliance Inventory - Goal
Week 1
|
21.85 score on a scale
Standard Deviation 5.28
|
—
|
|
Working Alliance Inventory - Goal
Week 2
|
23.17 score on a scale
Standard Deviation 3.83
|
—
|
|
Working Alliance Inventory - Goal
Week 3
|
23.98 score on a scale
Standard Deviation 3.81
|
—
|
|
Working Alliance Inventory - Goal
Week 4
|
25.05 score on a scale
Standard Deviation 2.95
|
—
|
|
Working Alliance Inventory - Goal
Week 5
|
24.85 score on a scale
Standard Deviation 3.23
|
—
|
|
Working Alliance Inventory - Goal
Week 6
|
25.1 score on a scale
Standard Deviation 3.22
|
—
|
|
Working Alliance Inventory - Goal
Week 7
|
25.63 score on a scale
Standard Deviation 3
|
—
|
|
Working Alliance Inventory - Goal
Week 8
|
26.21 score on a scale
Standard Deviation 2.33
|
—
|
SECONDARY outcome
Timeframe: Intervention weeks 1-8Population: All participants in the PEERS intervention with at least one assessment completed
Working alliance was measured on a weekly basis only in the intervention arm with the Working Alliance Inventory-SF. The survey has 12 items with subscales that measure affective bond, and agreement on tasks and goals and are scored using a Likert scale. The bond subscore was calculated by summing items 3, 5, 7, and 9. The subscale ranges from 4-28. A higher subscore indicates higher affective bond.
Outcome measures
| Measure |
PEERS
n=69 Participants
Peer mentors who have experience of depression are trained and supervised to deliver depression care. Peers will meet with depressed older adults for 8 weekly meeting lasting approximately 45 minutes. Peer mentors will provide social support defined as emotional, informational and appraisal support that includes coping strategies. Peers will be supervised by a mental health professional.
PEERS: Peer mentors deliver depression care that include social support and coping skills, focused on goal setting and small behavioral changes.
|
Social Interaction
A study staff member will provide eight weekly social interaction visits and phone calls to the depressed older adult.
Social interaction: Study staff will provide a combination of 8 social interaction visits and phone calls to the participants randomized to this condition.
|
|---|---|---|
|
Working Alliance Inventory - Bond
Week 1
|
23.28 score on a scale
Standard Deviation 5.14
|
—
|
|
Working Alliance Inventory - Bond
Week 2
|
24.49 score on a scale
Standard Deviation 3.38
|
—
|
|
Working Alliance Inventory - Bond
Week 3
|
24.63 score on a scale
Standard Deviation 3.31
|
—
|
|
Working Alliance Inventory - Bond
Week 4
|
25.02 score on a scale
Standard Deviation 2.95
|
—
|
|
Working Alliance Inventory - Bond
Week 5
|
25.02 score on a scale
Standard Deviation 3.38
|
—
|
|
Working Alliance Inventory - Bond
Week 6
|
25.45 score on a scale
Standard Deviation 3.02
|
—
|
|
Working Alliance Inventory - Bond
Week 7
|
25.51 score on a scale
Standard Deviation 2.86
|
—
|
|
Working Alliance Inventory - Bond
Week 8
|
26.17 score on a scale
Standard Deviation 2.53
|
—
|
SECONDARY outcome
Timeframe: Intervention weeks 1-8Population: All participants in the PEERS intervention with at least one assessment completed
Working alliance was measured on a weekly basis only in the intervention arm with the Working Alliance Inventory-SF. The survey has 12 items with subscales that measure affective bond, and agreement on tasks and goals and are scored using a Likert scale. The task subscore was calculated by summing items 2, 4, 10, and 12. The subscale ranges from 4-28. A higher subscore indicates higher agreement on tasks.
Outcome measures
| Measure |
PEERS
n=69 Participants
Peer mentors who have experience of depression are trained and supervised to deliver depression care. Peers will meet with depressed older adults for 8 weekly meeting lasting approximately 45 minutes. Peer mentors will provide social support defined as emotional, informational and appraisal support that includes coping strategies. Peers will be supervised by a mental health professional.
PEERS: Peer mentors deliver depression care that include social support and coping skills, focused on goal setting and small behavioral changes.
|
Social Interaction
A study staff member will provide eight weekly social interaction visits and phone calls to the depressed older adult.
Social interaction: Study staff will provide a combination of 8 social interaction visits and phone calls to the participants randomized to this condition.
|
|---|---|---|
|
Working Alliance Inventory - Task
Week 1
|
21.24 score on a scale
Standard Deviation 4.39
|
—
|
|
Working Alliance Inventory - Task
Week 2
|
20.97 score on a scale
Standard Deviation 4.15
|
—
|
|
Working Alliance Inventory - Task
Week 3
|
22.67 score on a scale
Standard Deviation 4.12
|
—
|
|
Working Alliance Inventory - Task
Week 4
|
23.13 score on a scale
Standard Deviation 4.32
|
—
|
|
Working Alliance Inventory - Task
Week 5
|
23.03 score on a scale
Standard Deviation 4.25
|
—
|
|
Working Alliance Inventory - Task
Week 6
|
23.31 score on a scale
Standard Deviation 4.11
|
—
|
|
Working Alliance Inventory - Task
Week 7
|
24.12 score on a scale
Standard Deviation 3.82
|
—
|
|
Working Alliance Inventory - Task
Week 8
|
24.69 score on a scale
Standard Deviation 3.62
|
—
|
SECONDARY outcome
Timeframe: Baseline, post-intervention (8-week), 3 months after intervention, 6 months after intervention, 9 months after intervention, 12 months after interventionPopulation: All participants with at least one assessment completed
The 20-item R-UCLA loneliness scale measures one's subjective feelings of loneliness as well as feelings of social isolation. Items are summed to create a score. The scores range from 20-80 and higher scores indicating higher level of loneliness. A total score of 20-34 represents low degree of loneliness; 35-49 represent moderate degree of loneliness; 50-64 represent moderately high degree of loneliness; and 65 or above represent high degree of loneliness.
Outcome measures
| Measure |
PEERS
n=69 Participants
Peer mentors who have experience of depression are trained and supervised to deliver depression care. Peers will meet with depressed older adults for 8 weekly meeting lasting approximately 45 minutes. Peer mentors will provide social support defined as emotional, informational and appraisal support that includes coping strategies. Peers will be supervised by a mental health professional.
PEERS: Peer mentors deliver depression care that include social support and coping skills, focused on goal setting and small behavioral changes.
|
Social Interaction
n=65 Participants
A study staff member will provide eight weekly social interaction visits and phone calls to the depressed older adult.
Social interaction: Study staff will provide a combination of 8 social interaction visits and phone calls to the participants randomized to this condition.
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|---|---|---|
|
UCLA Loneliness Scale
Baseline
|
51.54 score on a scale
Standard Deviation 15.75
|
47.67 score on a scale
Standard Deviation 15.43
|
|
UCLA Loneliness Scale
Post-intervention
|
44.56 score on a scale
Standard Deviation 14.91
|
42.72 score on a scale
Standard Deviation 12.69
|
|
UCLA Loneliness Scale
3 Months
|
43.9 score on a scale
Standard Deviation 13.5
|
39.24 score on a scale
Standard Deviation 12.91
|
|
UCLA Loneliness Scale
6 Months
|
41.79 score on a scale
Standard Deviation 16.24
|
42.52 score on a scale
Standard Deviation 13.44
|
|
UCLA Loneliness Scale
9 Months
|
43.71 score on a scale
Standard Deviation 17.05
|
39.94 score on a scale
Standard Deviation 14.12
|
|
UCLA Loneliness Scale
12 Months
|
42.93 score on a scale
Standard Deviation 17.76
|
40.17 score on a scale
Standard Deviation 14.56
|
SECONDARY outcome
Timeframe: Baseline, post-intervention (8-week), 3 months after intervention, 6 months after intervention, 9 months after intervention, 12 months after interventionPopulation: All participants with at least one assessment completed
The General Self-Efficacy Scale assess a general sense of perceived self-efficacy with the aim in mind to predict coping with daily hassles as well as adaptation after experiencing all kinds of stressful life events. GSES score is calculated by summing all item scores. The score ranges from 10-40 and higher scores indicating more self-efficacy.
Outcome measures
| Measure |
PEERS
n=69 Participants
Peer mentors who have experience of depression are trained and supervised to deliver depression care. Peers will meet with depressed older adults for 8 weekly meeting lasting approximately 45 minutes. Peer mentors will provide social support defined as emotional, informational and appraisal support that includes coping strategies. Peers will be supervised by a mental health professional.
PEERS: Peer mentors deliver depression care that include social support and coping skills, focused on goal setting and small behavioral changes.
|
Social Interaction
n=65 Participants
A study staff member will provide eight weekly social interaction visits and phone calls to the depressed older adult.
Social interaction: Study staff will provide a combination of 8 social interaction visits and phone calls to the participants randomized to this condition.
|
|---|---|---|
|
General Self-Efficacy Scale
Post-intervention
|
27.98 score on a scale
Standard Deviation 5.33
|
27.92 score on a scale
Standard Deviation 4.59
|
|
General Self-Efficacy Scale
3 Months
|
27.93 score on a scale
Standard Deviation 5.21
|
26.62 score on a scale
Standard Deviation 3.91
|
|
General Self-Efficacy Scale
6 Months
|
26.15 score on a scale
Standard Deviation 5.33
|
27.91 score on a scale
Standard Deviation 4.06
|
|
General Self-Efficacy Scale
9 Months
|
27.39 score on a scale
Standard Deviation 4.7
|
28.65 score on a scale
Standard Deviation 4.28
|
|
General Self-Efficacy Scale
12 Months
|
27.93 score on a scale
Standard Deviation 3.8
|
28 score on a scale
Standard Deviation 4.93
|
SECONDARY outcome
Timeframe: Baseline, post-intervention (8-week), 3 months after intervention, 6 months after intervention, 9 months after intervention, 12 months after interventionPopulation: All participants with at least one assessment completed
The Brief-COPE is a 28 item self-report questionnaire designed to measure effective and ineffective ways to cope with a stressful life event. Reliance on adaptive coping strategies were calculated as the sum of the following subscales: active coping (item 2, 7), emotional support (item 5, 15), use of informational support (item 10, 23), positive reframing (item 12, 17), planning (item 14,25), acceptance (item 20, 24), religion (item 22, 27). Each of the subscales ranges from 2-8. The range of scores for adaptive coping is 14-56, with higher scores indicating higher adaptive coping.
Outcome measures
| Measure |
PEERS
n=69 Participants
Peer mentors who have experience of depression are trained and supervised to deliver depression care. Peers will meet with depressed older adults for 8 weekly meeting lasting approximately 45 minutes. Peer mentors will provide social support defined as emotional, informational and appraisal support that includes coping strategies. Peers will be supervised by a mental health professional.
PEERS: Peer mentors deliver depression care that include social support and coping skills, focused on goal setting and small behavioral changes.
|
Social Interaction
n=65 Participants
A study staff member will provide eight weekly social interaction visits and phone calls to the depressed older adult.
Social interaction: Study staff will provide a combination of 8 social interaction visits and phone calls to the participants randomized to this condition.
|
|---|---|---|
|
Brief COPE - Adaptive Coping
Post-intervention
|
44.12 score on a scale
Standard Deviation 8.5
|
41.31 score on a scale
Standard Deviation 7.43
|
|
Brief COPE - Adaptive Coping
3 Months
|
44.5 score on a scale
Standard Deviation 7.86
|
39.62 score on a scale
Standard Deviation 7.87
|
|
Brief COPE - Adaptive Coping
6 Months
|
42.7 score on a scale
Standard Deviation 7.44
|
41.22 score on a scale
Standard Deviation 6.99
|
|
Brief COPE - Adaptive Coping
9 Months
|
44.36 score on a scale
Standard Deviation 8.13
|
42.64 score on a scale
Standard Deviation 7.24
|
|
Brief COPE - Adaptive Coping
12 Months
|
44.08 score on a scale
Standard Deviation 7.78
|
39.57 score on a scale
Standard Deviation 9.22
|
Adverse Events
PEERS
Serious events: 1 serious events
Other events: 0 other events
Deaths: 1 deaths
Social Interaction
Serious events: 4 serious events
Other events: 0 other events
Deaths: 2 deaths
Serious adverse events
| Measure |
PEERS
n=75 participants at risk
Peer mentors who have experience of depression are trained and supervised to deliver depression care. Peers will meet with depressed older adults for 8 weekly meeting lasting approximately 45 -60 minutes. Peer mentors will provide social support defined as emotional, informational and appraisal support that includes coping strategies. Peers will be supervised by a mental health professional.
PEERS: Peer mentors deliver depression care that include social support and coping skills, focused on goal setting and small behavioral changes.
|
Social Interaction
n=74 participants at risk
A study staff member will provide eight weekly social interaction phone calls to the depressed older adult.
Social interaction: Study staff will provide a social interaction phone calls to the participants randomized to this condition.
|
|---|---|---|
|
Respiratory, thoracic and mediastinal disorders
Hospitalization
|
0.00%
0/75 • Adverse event data is collected through study completion, an average of 18 months.
|
1.4%
1/74 • Number of events 1 • Adverse event data is collected through study completion, an average of 18 months.
|
|
General disorders
Death
|
0.00%
0/75 • Adverse event data is collected through study completion, an average of 18 months.
|
1.4%
1/74 • Number of events 1 • Adverse event data is collected through study completion, an average of 18 months.
|
|
General disorders
Admission to Hospice
|
0.00%
0/75 • Adverse event data is collected through study completion, an average of 18 months.
|
1.4%
1/74 • Number of events 1 • Adverse event data is collected through study completion, an average of 18 months.
|
|
Reproductive system and breast disorders
Death
|
1.3%
1/75 • Number of events 1 • Adverse event data is collected through study completion, an average of 18 months.
|
0.00%
0/74 • Adverse event data is collected through study completion, an average of 18 months.
|
|
Respiratory, thoracic and mediastinal disorders
Death
|
0.00%
0/75 • Adverse event data is collected through study completion, an average of 18 months.
|
1.4%
1/74 • Number of events 1 • Adverse event data is collected through study completion, an average of 18 months.
|
Other adverse events
Adverse event data not reported
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place