Trial Outcomes & Findings for Translating Peer-to-Peer Support Into a Clinical Setting (NCT NCT04313283)

NCT ID: NCT04313283

Last Updated: 2023-03-10

Results Overview

Autism Parenting Stress Index (APSI): This measure includes 13 items that assess core autism symptoms, comorbid behaviors, and comorbid physical behaviors. Each item is based on a 5-point rating scale with descriptors for 0, 1, 2, 3, and 5. Possible range is 0-65. Higher scores indicate more parenting stress.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

36 participants

Primary outcome timeframe

Pre-intervention and post-intervention at 12 weeks

Results posted on

2023-03-10

Participant Flow

We recruited participants whose child was waitlisted for an autism or developmental evaluation. 36 participants consented to participate in the single-arm study, but 17 of them did not receive the intervention because they did not complete baseline measures (n=12) or did not begin the intervention (n=5). Thus, 19 people began the intervention. Of these, 15 completed the intervention and all data points; the remaining 4 only completed part of the intervention and did not complete all data points.

Participant milestones

Participant milestones
Measure
Parents Taking Action
A peer-led intervention, Parents Taking Action is the psychoeducational and child behavior management intervention led by trained Parent Leaders for 12 weeks. Parents Taking Action: A peer-led intervention, Parents Taking Action is the psychoeducational and child behavior management intervention led by trained Parent Leaders.
Overall Study
STARTED
19
Overall Study
COMPLETED
15
Overall Study
NOT COMPLETED
4

Reasons for withdrawal

Reasons for withdrawal
Measure
Parents Taking Action
A peer-led intervention, Parents Taking Action is the psychoeducational and child behavior management intervention led by trained Parent Leaders for 12 weeks. Parents Taking Action: A peer-led intervention, Parents Taking Action is the psychoeducational and child behavior management intervention led by trained Parent Leaders.
Overall Study
did not complete intervention
4

Baseline Characteristics

Translating Peer-to-Peer Support Into a Clinical Setting

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Parents Taking Action
n=15 Participants
A peer-led intervention, Parents Taking Action is the psychoeducational and child behavior management intervention led by trained Parent Leaders for 12 weeks. Parents Taking Action: A peer-led intervention, Parents Taking Action is the psychoeducational and child behavior management intervention led by trained Parent Leaders.
Age, Continuous
37.3 years
STANDARD_DEVIATION 11.2 • n=5 Participants
Sex: Female, Male
Female
14 Participants
n=5 Participants
Sex: Female, Male
Male
1 Participants
n=5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=5 Participants
Race (NIH/OMB)
Asian
0 Participants
n=5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=5 Participants
Race (NIH/OMB)
Black or African American
15 Participants
n=5 Participants
Race (NIH/OMB)
White
0 Participants
n=5 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=5 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
Employment Status
Employed full-time
5 Participants
n=5 Participants
Employment Status
Employed part-time
4 Participants
n=5 Participants
Employment Status
Self-employed
4 Participants
n=5 Participants
Employment Status
Unemployed
2 Participants
n=5 Participants
Marital Status
Never married
8 Participants
n=5 Participants
Marital Status
Married
5 Participants
n=5 Participants
Marital Status
Divorced
1 Participants
n=5 Participants
Marital Status
Other
1 Participants
n=5 Participants
Education Level
High school graduate
9 Participants
n=5 Participants
Education Level
College graduate
3 Participants
n=5 Participants
Education Level
Graduate/professional school
3 Participants
n=5 Participants
Annual Household Income (USD)
<$10,000
5 Participants
n=5 Participants
Annual Household Income (USD)
$10,000 - $29,999
3 Participants
n=5 Participants
Annual Household Income (USD)
$30,000 - $49,999
3 Participants
n=5 Participants
Annual Household Income (USD)
$50,000 - $69,999
1 Participants
n=5 Participants
Annual Household Income (USD)
≥$70,000
1 Participants
n=5 Participants
Annual Household Income (USD)
Don't know/not sure
2 Participants
n=5 Participants

PRIMARY outcome

Timeframe: Pre-intervention and post-intervention at 12 weeks

Autism Parenting Stress Index (APSI): This measure includes 13 items that assess core autism symptoms, comorbid behaviors, and comorbid physical behaviors. Each item is based on a 5-point rating scale with descriptors for 0, 1, 2, 3, and 5. Possible range is 0-65. Higher scores indicate more parenting stress.

Outcome measures

Outcome measures
Measure
Parents Taking Action
n=15 Participants
A peer-led intervention, Parents Taking Action is the psychoeducational and child behavior management intervention led by trained Parent Leaders for 12 weeks. Parents Taking Action: A peer-led intervention, Parents Taking Action is the psychoeducational and child behavior management intervention led by trained Parent Leaders.
Parenting Stress
Pre-intervention
14.4 score on a scale
Standard Deviation 11.4
Parenting Stress
Post-intervention
12.2 score on a scale
Standard Deviation 8.52

SECONDARY outcome

Timeframe: Pre-intervention and post-intervention at 12 weeks

Center for Epidemiological Studies-Depression (CES-D)- This measure contains 20 items assess 4 separate factors: depressive affect, somatic symptoms, positive affect, and interpersonal relations. Each item is based on a 4-point rating scale with descriptors for 0, 1, 2, and 3. Possible range is 0-60. A score of 16 points or more considered depressed.

Outcome measures

Outcome measures
Measure
Parents Taking Action
n=15 Participants
A peer-led intervention, Parents Taking Action is the psychoeducational and child behavior management intervention led by trained Parent Leaders for 12 weeks. Parents Taking Action: A peer-led intervention, Parents Taking Action is the psychoeducational and child behavior management intervention led by trained Parent Leaders.
Depression
Pre-intervention
15.2 score on a scale
Standard Deviation 9.7
Depression
Post-intervention
10.6 score on a scale
Standard Deviation 8.35

SECONDARY outcome

Timeframe: Pre-intervention and post-intervention at 12 weeks

Family Outcomes Survey-Revised (FOS-R): This measure was developed to provide child and family outcomes for evaluation the effectiveness of early intervention program. This measure includes 24 items assessing five outcomes (1) family needs/strengths (4 items); (2) advocacy (5 items); (3) child learning support (4 items); (4) social support (5 items); and (5) community access (6 items). Each item is based on a 5-point rating scale with descriptors for 1, 2, 3, 4, and 5. Possible range is 24-120. Higher scores indicate better family functioning.

Outcome measures

Outcome measures
Measure
Parents Taking Action
n=15 Participants
A peer-led intervention, Parents Taking Action is the psychoeducational and child behavior management intervention led by trained Parent Leaders for 12 weeks. Parents Taking Action: A peer-led intervention, Parents Taking Action is the psychoeducational and child behavior management intervention led by trained Parent Leaders.
Family Functioning
Pre-intervention
85.5 score on a scale
Standard Deviation 12.3
Family Functioning
Post-intervention
99.7 score on a scale
Standard Deviation 14.4

SECONDARY outcome

Timeframe: Weekly through intervention (12 weeks total)

Population: Parent Leaders report fidelity 0-100 on each session they have with intervention participants.

Procedural Fidelity Checklist Self-Assessment for Promotora Home Visits: This measurement was developed to evaluate Parent Leaders' fidelity on the program delivery. This measure includes 16 items the Parent Leader completes after every program session. Each item is based on two responses: (1) I did this; (2) I did not this. Possible range is 0-100. Higher scores indicate less fidelity.

Outcome measures

Outcome measures
Measure
Parents Taking Action
n=183 intervention sessions
A peer-led intervention, Parents Taking Action is the psychoeducational and child behavior management intervention led by trained Parent Leaders for 12 weeks. Parents Taking Action: A peer-led intervention, Parents Taking Action is the psychoeducational and child behavior management intervention led by trained Parent Leaders.
Fidelity
98 score on a scale
Standard Deviation .04

SECONDARY outcome

Timeframe: Pre-intervention and post-intervention at 12 weeks

Nisonger Child Behavior Rating Form (NCBRF)- This measure includes 76 item in two sections, reported separately: positive social behavior and problem behavior. Each item is based on a 4-point rating scale with descriptors for 0, 1, 2, and 3. Section 1 (positive social behavior) contains 10 items and scores range from 0-30. Higher scores indicate more positive social behavior. Section 2 (problem behavior) contains 66 items and scores range from 0-198. Higher scores indicate more child behavior problems.

Outcome measures

Outcome measures
Measure
Parents Taking Action
n=15 Participants
A peer-led intervention, Parents Taking Action is the psychoeducational and child behavior management intervention led by trained Parent Leaders for 12 weeks. Parents Taking Action: A peer-led intervention, Parents Taking Action is the psychoeducational and child behavior management intervention led by trained Parent Leaders.
Child Behavior
Pre-intervention (positive social behavior total score)
11.0 score on a scale
Standard Deviation 4.4
Child Behavior
Post-intervention (positive social behavior total score)
12.1 score on a scale
Standard Deviation 5.5
Child Behavior
Pre-intervention (problem behavior total score)
45.3 score on a scale
Standard Deviation 32.6
Child Behavior
Post-intervention (problem behavior total score)
37.5 score on a scale
Standard Deviation 19.7

Adverse Events

Parents Taking Action

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Sarah Dababnah

University of Maryland Baltimore

Phone: 14107068076

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place