Why in Hospital After VATS Lobectomy

NCT ID: NCT04294108

Last Updated: 2021-11-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

160 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-04-20

Study Completion Date

2021-09-18

Brief Summary

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The study aims to identify specific or potential reasons that prolong the length of hospital stay after video-assisted thoracoscopic surgery lobectomy.

The hypothesis is that patients who are still in hospital after video-assisted thoracoscopic surgery lobectomy are associated with prolonged air leak, infection, pneumonia, atrial fibrillation or other complications or social factors.

Detailed Description

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Conditions

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Carcinoma, Non-Small-Cell Lung Pain, Postoperative Postoperative Nausea and Vomiting Infection Air Leakage Atrial Fibrillation

Keywords

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in hospital lobectomy video-assisted thoracoscopic surgery

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients underwent VATS lobectomy

All consecutive patients scheduled for video-assisted thoracoscopic surgery lobectomy.

Prolong in-hospital stay

Intervention Type OTHER

Patients have a longer length of hospital stay than the common recommendation.

Interventions

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Prolong in-hospital stay

Patients have a longer length of hospital stay than the common recommendation.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients referred to elective VATS lobectomy
* Speaks and understands Danish
* Informed consent obtained

Exclusion Criteria

•Age \< 18 years
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Rigshospitalet, Denmark

OTHER

Sponsor Role lead

Responsible Party

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Lin Huang

Medical Doctor/ Research Fellow

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Lin Huang, MD

Role: PRINCIPAL_INVESTIGATOR

Rigshospitalet, Denmark

Henrik Kehlet, MD, DMSc

Role: STUDY_DIRECTOR

Rigshospitalet, Denmark

Rene H Petersen, MD, PhD

Role: STUDY_CHAIR

Rigshospitalet, Denmark

Locations

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Rigshospitalet

Copenhagen, , Denmark

Site Status

Countries

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Denmark

References

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Laursen LO, Petersen RH, Hansen HJ, Jensen TK, Ravn J, Konge L. Video-assisted thoracoscopic surgery lobectomy for lung cancer is associated with a lower 30-day morbidity compared with lobectomy by thoracotomy. Eur J Cardiothorac Surg. 2016 Mar;49(3):870-5. doi: 10.1093/ejcts/ezv205. Epub 2015 Jun 18.

Reference Type BACKGROUND
PMID: 26088592 (View on PubMed)

Agostini PJ, Lugg ST, Adams K, Smith T, Kalkat MS, Rajesh PB, Steyn RS, Naidu B, Rushton A, Bishay E. Risk factors and short-term outcomes of postoperative pulmonary complications after VATS lobectomy. J Cardiothorac Surg. 2018 Apr 12;13(1):28. doi: 10.1186/s13019-018-0717-6.

Reference Type BACKGROUND
PMID: 29673386 (View on PubMed)

Kehlet H. ERAS Implementation-Time To Move Forward. Ann Surg. 2018 Jun;267(6):998-999. doi: 10.1097/SLA.0000000000002720. No abstract available.

Reference Type BACKGROUND
PMID: 29462010 (View on PubMed)

Das-Neves-Pereira JC, Bagan P, Coimbra-Israel AP, Grimaillof-Junior A, Cesar-Lopez G, Milanez-de-Campos JR, Riquet M, Biscegli-Jatene F. Fast-track rehabilitation for lung cancer lobectomy: a five-year experience. Eur J Cardiothorac Surg. 2009 Aug;36(2):383-91; discussion 391-2. doi: 10.1016/j.ejcts.2009.02.020. Epub 2009 Mar 26.

Reference Type BACKGROUND
PMID: 19324571 (View on PubMed)

Holbek BL, Horsleben Petersen R, Kehlet H, Hansen HJ. Fast-track video-assisted thoracoscopic surgery: future challenges. Scand Cardiovasc J. 2016;50(2):78-82. doi: 10.3109/14017431.2015.1114665. Epub 2015 Dec 1.

Reference Type BACKGROUND
PMID: 26514281 (View on PubMed)

Batchelor TJP, Rasburn NJ, Abdelnour-Berchtold E, Brunelli A, Cerfolio RJ, Gonzalez M, Ljungqvist O, Petersen RH, Popescu WM, Slinger PD, Naidu B. Guidelines for enhanced recovery after lung surgery: recommendations of the Enhanced Recovery After Surgery (ERAS(R)) Society and the European Society of Thoracic Surgeons (ESTS). Eur J Cardiothorac Surg. 2019 Jan 1;55(1):91-115. doi: 10.1093/ejcts/ezy301.

Reference Type BACKGROUND
PMID: 30304509 (View on PubMed)

Husted H, Lunn TH, Troelsen A, Gaarn-Larsen L, Kristensen BB, Kehlet H. Why still in hospital after fast-track hip and knee arthroplasty? Acta Orthop. 2011 Dec;82(6):679-84. doi: 10.3109/17453674.2011.636682. Epub 2011 Nov 9.

Reference Type BACKGROUND
PMID: 22066560 (View on PubMed)

Munk-Madsen P, Eriksen JR, Kehlet H, Gogenur I. Why still in hospital after laparoscopic colorectal surgery within an enhanced recovery programme? Colorectal Dis. 2019 Dec;21(12):1438-1444. doi: 10.1111/codi.14762. Epub 2019 Aug 13.

Reference Type BACKGROUND
PMID: 31309661 (View on PubMed)

Wildgaard K, Petersen RH, Hansen HJ, Moller-Sorensen H, Ringsted TK, Kehlet H. Multimodal analgesic treatment in video-assisted thoracic surgery lobectomy using an intraoperative intercostal catheter. Eur J Cardiothorac Surg. 2012 May;41(5):1072-7. doi: 10.1093/ejcts/ezr151. Epub 2011 Dec 21.

Reference Type BACKGROUND
PMID: 22219442 (View on PubMed)

Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J, Jemal A. Global cancer statistics, 2012. CA Cancer J Clin. 2015 Mar;65(2):87-108. doi: 10.3322/caac.21262. Epub 2015 Feb 4.

Reference Type BACKGROUND
PMID: 25651787 (View on PubMed)

Marjanski T, Wnuk D, Bosakowski D, Szmuda T, Sawicka W, Rzyman W. Patients who do not reach a distance of 500 m during the 6-min walk test have an increased risk of postoperative complications and prolonged hospital stay after lobectomy. Eur J Cardiothorac Surg. 2015 May;47(5):e213-9. doi: 10.1093/ejcts/ezv049. Epub 2015 Feb 26.

Reference Type BACKGROUND
PMID: 25721817 (View on PubMed)

Other Identifiers

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H-20014489

Identifier Type: -

Identifier Source: org_study_id