Intervention Facilitates Oral Feeding in Premature Infants

NCT ID: NCT04283682

Last Updated: 2022-12-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

148 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-04-08

Study Completion Date

2022-05-30

Brief Summary

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Skin-to-skin combined with breastfeeding shortened the cycle of full-oral feeding in premature infants

Detailed Description

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This study is conducted at the level 3 NICU of the Children's Hospital of Fudan University, Shanghai, People's Republic of China, a tertiary medical center. Infants admitted to the NICU are all outborn infants.

The study is approved by the Ethics Committee of the Children's Hospital of Fudan University. Signed parental consent is obtained before participants'entry into the study. The RCT is conducted to evaluate the effectiveness of skin-to-skin combined with breastfeeding reduce the transition time from tube feeding to independent oral feeding.

The recruited infants are assigned to intervention group and control group.

Data are presented as means ± sds for continuous variables with normal distribution and percentages (%) for categorical variables. One-way analysis of variance and Fisher exact test is used to compare infants' baseline characteristics among the two groups. All statistical analyses are conducted using SPSS. A p value of less than 0.05 is regarded as statistically significant.

Conditions

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Premature

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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standard group

Feeding procedures follow clinical nursing practices

Group Type NO_INTERVENTION

No interventions assigned to this group

intervention group

At appropriate time to invite mothers of premature infants into the NICU for skin-to-skin and breastfeeding

Group Type EXPERIMENTAL

Early skin-to-skin combined with breast-feeding

Intervention Type BEHAVIORAL

Premature infants in the intervention group have access to skin-to-skin once a day for 1 hour at least once no ventilation support needed. During the skin-to-skin period,the breastfeeding is encouraged for about 5-10 minutes. The whole intervention stop until the baby achieve the full oral feeding.

Interventions

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Early skin-to-skin combined with breast-feeding

Premature infants in the intervention group have access to skin-to-skin once a day for 1 hour at least once no ventilation support needed. During the skin-to-skin period,the breastfeeding is encouraged for about 5-10 minutes. The whole intervention stop until the baby achieve the full oral feeding.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* gestational age ≤30 weeks
* birth weight \< 1500g
* age of admission \<72 hours
* no congenital malformation

Exclusion Criteria

* OI \> 40
* mother has trouble in communicating
Maximum Eligible Age

72 Hours

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Children's Hospital of Fudan University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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ling li Li

Role: STUDY_CHAIR

Wanyuan Road 399,Minhang District, Shanghai,China

Locations

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Children's Hospital of Fudan University

Shanghai, , China

Site Status

Countries

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China

References

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Li L, Wang L, Niu C, Liu C, Lv T, Ji F, Yu L, Yan W, Dou YL, Wang Y, Cao Y, Huang G, Hu X. Early skin contact combined with mother's breastfeeding to shorten the process of premature infants </= 30 weeks of gestation to achieve full oral feeding: the study protocol of a randomized controlled trial. Trials. 2021 Sep 17;22(1):637. doi: 10.1186/s13063-021-05605-x.

Reference Type DERIVED
PMID: 34535164 (View on PubMed)

Other Identifiers

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EKYY-2019-295

Identifier Type: -

Identifier Source: org_study_id

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