Trial Outcomes & Findings for Acceptance and Commitment Therapy for Older Adults (NCT NCT04280445)

Results Overview

Brief measure of quality of life (QoL) in older age.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

3 participants

Primary outcome timeframe

up to 20 weeks

Results posted on

2025-01-01

Participant Flow

Participant milestones

Participant milestones
Measure	Psychological Therapy All participants will receive psychological therapy. There will be no placebos or waiting list controlled participants to compare findings to. Psychological therapy: Acceptance and Commitment Therapy (ACT) is a trans-diagnostic approach which aims to promote better living by supporting clients through six key processes (e.g. mindfulness, values). ACT does not aim to reduce distress, rather its goal is to promote better living or a better quality of life despite distress (Hayes, Strosahl \& Wilson, 1999). ACT has been shown to have equal or superior efficacy to CBT with a number of psychological and physical health conditions (A-Tjak et al., 2015; Ruiz, 2012).
Overall Study STARTED	3
Overall Study COMPLETED	3
Overall Study NOT COMPLETED	0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Acceptance and Commitment Therapy for Older Adults

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	Psychological Therapy n=3 Participants All participants will receive psychological therapy. There will be no placebos or waiting list controlled participants to compare findings to. Psychological therapy: Acceptance and Commitment Therapy (ACT) is a trans-diagnostic approach which aims to promote better living by supporting clients through six key processes (e.g. mindfulness, values). ACT does not aim to reduce distress, rather its goal is to promote better living or a better quality of life despite distress (Hayes, Strosahl \& Wilson, 1999). ACT has been shown to have equal or superior efficacy to CBT with a number of psychological and physical health conditions (A-Tjak et al., 2015; Ruiz, 2012).
Age, Categorical <=18 years	0 Participants n=5 Participants
Age, Categorical Between 18 and 65 years	0 Participants n=5 Participants
Age, Categorical >=65 years	3 Participants n=5 Participants
Age, Continuous	72.67 years STANDARD_DEVIATION 5.86 • n=5 Participants
Sex: Female, Male Female	2 Participants n=5 Participants
Sex: Female, Male Male	1 Participants n=5 Participants
Race/Ethnicity, Customized White British	3 Participants n=5 Participants
Older People's Quality of Life questionnaire, brief version (OPQOL-brief)	43.67 units on a scale STANDARD_DEVIATION 7.57 • n=5 Participants
Hospital Anxiety and Depression Scale - Anxiety Subscale(HADS-A)	13.67 units on a scale STANDARD_DEVIATION 6.66 • n=5 Participants
Hospital Anxiety and Depression Scale - Depression Subscale (HADS-D)	9.67 units on a scale STANDARD_DEVIATION 3.06 • n=5 Participants
Comprehensive Assessment of Acceptance and Commitment Therapy processes, short-form,(CompACT-8)	20 units on a scale STANDARD_DEVIATION 1.73 • n=5 Participants

PRIMARY outcome

Timeframe: up to 20 weeks

Population: All participants completed baseline of 3 or 4 weeks. OPQOL-brief was used at baseline, mid, end, and follow-up point. Missing data was treated as missing. Mean score for all participants at one-month follow-up point shown below.

Brief measure of quality of life (QoL) in older age.

Outcome measures

Outcome measures
Measure	Psychological Therapy n=3 Participants All participants will receive psychological therapy. There will be no placebos or waiting list controlled participants to compare findings to. Psychological therapy: Acceptance and Commitment Therapy (ACT) is a trans-diagnostic approach which aims to promote better living by supporting clients through six key processes (e.g. mindfulness, values). ACT does not aim to reduce distress, rather its goal is to promote better living or a better quality of life despite distress (Hayes, Strosahl \& Wilson, 1999). ACT has been shown to have equal or superior efficacy to CBT with a number of psychological and physical health conditions (A-Tjak et al., 2015; Ruiz, 2012).
Change in Quality of Life Assessed Using the Older People's Quality of Life Questionnaire (OPQOL-brief).	43.33 score on a scale Standard Deviation 8.39

SECONDARY outcome

Timeframe: up to 5 weeks

A brief cognitive screening questionnaire which will be administered by the usual care team at the start of the study.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: up to 20 weeks

A brief measure of anxiety and depression that is less prone to conflation of physical health symptoms onto symptoms of psychological distress.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: up to 20 weeks

This consists of up to ten problem statements the client outlines at start of therapy and rates on a 7-point Likert scale for how much they have been bothered by the problem in the past week. They will then re-rate this before each therapy session and again at six-week follow-up.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: up to 20 weeks

A brief measure of patient rated outcomes in therapy session.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: up to 20 weeks

A brief measure of patient rated therapeutic alliance.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: up to 20 weeks

A qualitative measure of patient rated therapeutic alliance.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: up to 20 weeks

An ACT process measure.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: up to 20 weeks

A semi-structured interview to determine the participant's view on any change achieved during therapy. Delivered by a researcher other than the therapist.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: up to 20 weeks

A fidelity measure to ensure that sessions meet the requirements of ACT.

Outcome measures

Outcome data not reported

Adverse Events

Psychological Therapy

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr Daniell De Boos

Trent Doctorate in Clinical Psychology Programme, University of Nottingham, UK

Phone: +44 (0)115 84 67523

Email: [email protected]

Results disclosure agreements

Principal investigator is a sponsor employee
Publication restrictions are in place