The Effect of Exercise on Wound Healing While Off-loading

NCT ID: NCT04280016

Last Updated: 2021-10-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-05-14

Study Completion Date

2023-05-31

Brief Summary

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This study seeks to establish the effect of adding exercise to off-loading interventions on the healing time for people with diabetes mellitus and a foot ulcer. Hypothesis: Consistent with the literature, results are expected to resemble the accelerated healing seen when older adults exercised in the presence of wounds.

Detailed Description

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The purpose of this project is to establish the effect of the addition of exercise to an off-loading intervention on the healing time for people with diabetes mellitus and a foot ulcer.

While benefits of physical activity and exercise are clear, the benefit of exercise on wound healing in individuals with diabetes has not been elucidated. It is critical to better understand how prescribed exercise effects the healing speed in patients receiving wound care with appropriate off-loading. If exercise does decrease healing time, the benefit to the patient may include lower cost, decreased risk of infection, decreased burden on a caregiver, and improved quality of life.

Conditions

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Diabetic Foot Ulcer

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

A pilot study using retrospective chart review and non-randomized controlled trial methodology (single group).
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

The outcome assessor will be unaware of how much the participant participated in the exercise program. Exercise will occur away from the treatment area so that the care provider will be unaware of whether or not a patient is participating in the study.

Study Groups

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Exercise Added to Off-loading

Participants in this arm will participate in exercise at the healthcare facility one time a week (away from where wound care is provided) and be instructed in a home exercise program that they will be encouraged to perform at least three days per week with no more than two days between sessions. Wound care will continue at the facility as is standard, utilizing off-loading.

Group Type EXPERIMENTAL

Exercise

Intervention Type BEHAVIORAL

Participants will participate in an exercise session with non-weight-bearing exercise that the participant is able to perform with off-loading (e.g. total contact cast) intact. They will also be instructed in a home exercise program so that exercise can be performed three days per week with no more than two days between sessions. These participants will also receive standard wound care with off-loading.

Interventions

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Exercise

Participants will participate in an exercise session with non-weight-bearing exercise that the participant is able to perform with off-loading (e.g. total contact cast) intact. They will also be instructed in a home exercise program so that exercise can be performed three days per week with no more than two days between sessions. These participants will also receive standard wound care with off-loading.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Have diabetes
* Have an active plantar ulceration
* With or without peripheral neuropathy
* Able to safely exercise
* Receiving care for their plantar ulceration, including off-loading

Exclusion Criteria

\- Presence of an untreated infection, osteomyelitis, or gangrene
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mercer University

OTHER

Sponsor Role lead

Responsible Party

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Deborah M. Wendland, Ph.D.

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Deborah M. Wendland

Role: PRINCIPAL_INVESTIGATOR

Mercer University

Locations

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Piedmont Healthcare

Atlanta, Georgia, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Deborah M. Wendland, PhD

Role: CONTACT

6785476775

Teri Biven, DPT

Role: CONTACT

404.605.2743

Facility Contacts

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Teri Biven, DPT

Role: primary

404-605-2743

Other Identifiers

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H1908192

Identifier Type: -

Identifier Source: org_study_id