The Role of Ophthalmologic Tests and EEG Imaging in Alzheimer's Disease

NCT ID: NCT04277767

Last Updated: 2021-04-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-09-01

Study Completion Date

2023-07-01

Brief Summary

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Alzheimer's disease (AD) is a prevalent, long-term progressive degenerative disorder with great social impact. It is currently thought that, in addition to neurodegeneration, vascular changes also play a role in the pathophysiology of the disease. Meantime, EEG resting state has also demonstrated significant change in patients with AD in neuroscience research area. Thus, the combination of these sensitive biomarkers would lead to a potential new biomarker for detection of AD, which has higher specificity and sensitivity.

Detailed Description

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Conditions

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Mild Cognitive Impairment

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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mild cognitive impairment (MCI)

observational

observational

Intervention Type DIAGNOSTIC_TEST

No intervention

Patients with mild to moderate AD

observational

observational

Intervention Type DIAGNOSTIC_TEST

No intervention

Normal controls

observational

observational

Intervention Type DIAGNOSTIC_TEST

No intervention

Interventions

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observational

No intervention

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Clinical diagnosis of Alzheimer's Disease

Exclusion Criteria

* neurologic disorders
* psychiatric disorders
Minimum Eligible Age

50 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Zhongshan Ophthalmic Center, Sun Yat-sen University

OTHER

Sponsor Role lead

Responsible Party

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Jin Yuan

assistant dean

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jin Yuan, phD

Role: PRINCIPAL_INVESTIGATOR

Zhongshan Ophthalmological Center, Sun Yat-sen University

Locations

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Zhongshan Ophthalmic Center

Guangzhou, Guangdong, China

Site Status

Countries

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China

Central Contacts

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Jin Yuan, phD

Role: CONTACT

13825141659

Li Gu, phD

Role: CONTACT

+8615889937313

Facility Contacts

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Li Gu, Dr.

Role: primary

15889937313 ext. +86

Other Identifiers

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AD2020

Identifier Type: -

Identifier Source: org_study_id

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