Trial Outcomes & Findings for Liver Cancer Community Education (NCT NCT04272619)

NCT ID: NCT04272619

Last Updated: 2025-01-08

Results Overview

Liver cancer knowledge will be measured through four true/false items. Responses will be summed for a total liver cancer knowledge score. Score ranges run from 0-4, with higher scores indicating more knowledge. Change in knowledge is measured by subtracting baseline knowledge score from the post-intervention knowledge score. Change scores may range from -4 to 4, with positive scores indicating an increase in knowledge. Higher positive scores indicate a larger increase in knowledge.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

67 participants

Primary outcome timeframe

Baseline, 30 minutes

Results posted on

2025-01-08

Participant Flow

Participant milestones

Participant milestones
Measure	Liver Cancer Education LIVE-R Life Education: A health educator will present participants with a 30-minute PowerPoint presentation containing educational information about liver cancer risk, screening, prevention, symptoms, and treatments, as well as introduce the concept of neighborhood health (e.g., rates of liver cancer and related risk factors in a census tract and how that might influence individual cancer risk).
Overall Study STARTED	67
Overall Study COMPLETED	67
Overall Study NOT COMPLETED	0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Liver Cancer Community Education

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	Liver Cancer Education n=67 Participants LIVE-R Life Education: A health educator will present participants with a 30-minute PowerPoint presentation containing educational information about liver cancer risk, screening, prevention, symptoms, and treatments, as well as introduce the concept of neighborhood health (e.g., rates of liver cancer and related risk factors in a census tract and how that might influence individual cancer risk).
Age, Continuous	50.25 years STANDARD_DEVIATION 18.90 • n=5 Participants
Sex: Female, Male Female	50 Participants n=5 Participants
Sex: Female, Male Male	17 Participants n=5 Participants
Ethnicity (NIH/OMB) Hispanic or Latino	29 Participants n=5 Participants
Ethnicity (NIH/OMB) Not Hispanic or Latino	38 Participants n=5 Participants
Ethnicity (NIH/OMB) Unknown or Not Reported	0 Participants n=5 Participants
Race (NIH/OMB) American Indian or Alaska Native	0 Participants n=5 Participants
Race (NIH/OMB) Asian	1 Participants n=5 Participants
Race (NIH/OMB) Native Hawaiian or Other Pacific Islander	0 Participants n=5 Participants
Race (NIH/OMB) Black or African American	22 Participants n=5 Participants
Race (NIH/OMB) White	21 Participants n=5 Participants
Race (NIH/OMB) More than one race	2 Participants n=5 Participants
Race (NIH/OMB) Unknown or Not Reported	21 Participants n=5 Participants
Region of Enrollment United States	67 participants n=5 Participants

PRIMARY outcome

Timeframe: Baseline, 30 minutes

Population: Five participants skipped the knowledge items on either the pre-test or the post-test.

Liver cancer knowledge will be measured through four true/false items. Responses will be summed for a total liver cancer knowledge score. Score ranges run from 0-4, with higher scores indicating more knowledge. Change in knowledge is measured by subtracting baseline knowledge score from the post-intervention knowledge score. Change scores may range from -4 to 4, with positive scores indicating an increase in knowledge. Higher positive scores indicate a larger increase in knowledge.

Outcome measures

Outcome measures
Measure	Liver Cancer Education n=62 Participants LIVE-R Life Education: A health educator will present participants with a 30-minute PowerPoint presentation containing educational information about liver cancer risk, screening, prevention, symptoms, and treatments, as well as introduce the concept of neighborhood health (e.g., rates of liver cancer and related risk factors in a census tract and how that might influence individual cancer risk).
Change in Mean Liver Cancer Knowledge	1.26 score on a scale Standard Deviation 1.09

PRIMARY outcome

Timeframe: Baseline, 30 minutes

General interest in learning about neighborhood health will be measured through a single item asking, on a scale from strongly agree to strongly disagree, whether the participant would like to learn about liver cancer in their own neighborhood. Scores range from 1 to 5, with higher scores indicating more interest in learning about neighborhood health from a healthcare provider. Change in interest is measured by subtracting the baseline interest score from the post-intervention interest score. Change scores may range from -4 to 4, with positive scores indicating an increase in interest. Higher positive scores indicate a larger increase in interest.

Outcome measures

Outcome measures
Measure	Liver Cancer Education n=67 Participants LIVE-R Life Education: A health educator will present participants with a 30-minute PowerPoint presentation containing educational information about liver cancer risk, screening, prevention, symptoms, and treatments, as well as introduce the concept of neighborhood health (e.g., rates of liver cancer and related risk factors in a census tract and how that might influence individual cancer risk).
Change in General Interest in Learning About Neighborhood Health	-1.81 score on a scale Standard Deviation 1.50

PRIMARY outcome

Timeframe: Baseline, 30 minutes

Population: Two participants did not answer this item at pre- or post-test.

Interest in learning about neighborhood health from a healthcare provider will be measured through a single item asking, on a scale from strongly agree to strongly disagree, whether the participant would like to learn about liver cancer in their own neighborhood from their doctor. Scores range from 1 to 5, with higher scores indicating more interest in learning about neighborhood health from a healthcare provider. Change in interest is measured by subtracting the baseline interest score from the post-intervention interest score. Change scores may range from -4 to 4, with positive scores indicating an increase in interest. Higher positive scores indicate a larger increase in interest.

Outcome measures

Outcome measures
Measure	Liver Cancer Education n=65 Participants LIVE-R Life Education: A health educator will present participants with a 30-minute PowerPoint presentation containing educational information about liver cancer risk, screening, prevention, symptoms, and treatments, as well as introduce the concept of neighborhood health (e.g., rates of liver cancer and related risk factors in a census tract and how that might influence individual cancer risk).
Change in Interest in Learning About Neighborhood Health From a Healthcare Provider	-0.95 score on a scale Standard Deviation 1.46

PRIMARY outcome

Timeframe: Baseline, 30 minutes

Interest in learning about neighborhood health from other sources will be measured through a single item asking, on a scale from strongly agree to strongly disagree, whether the participant would like to learn about liver cancer in their own neighborhood from non-medical sources (e.g., website or brochure). Scores range from 1 to 5, with higher scores indicating more interest in learning about neighborhood health from other sources. Change in interest is measured by subtracting the baseline interest score from the post-intervention interest score. Change scores may range from -4 to 4, with positive scores indicating an increase in interest. Higher positive scores indicate a larger increase in interest.

Outcome measures

Outcome measures
Measure	Liver Cancer Education n=67 Participants LIVE-R Life Education: A health educator will present participants with a 30-minute PowerPoint presentation containing educational information about liver cancer risk, screening, prevention, symptoms, and treatments, as well as introduce the concept of neighborhood health (e.g., rates of liver cancer and related risk factors in a census tract and how that might influence individual cancer risk).
Change in Interest in Learning About Neighborhood Health From Other Sources	-0.90 score on a scale Standard Deviation 1.72

PRIMARY outcome

Timeframe: Baseline, 30 minutes

Population: Three participants did not respond to this item at pre- or post-survey.

Interest in discussing high liver cancer risk with a healthcare provider will be measured through a single item asking, on a scale from strongly agree to strongly disagree, whether the participant would be likely to discuss their liver cancer risk with a doctor if they learned they lived in a high-risk area. Scores range from 1 to 5, with higher scores indicating more interest in discussing liver cancer risk with a healthcare provider. Change in interest is measured by subtracting the baseline interest score from the post-intervention interest score. Change scores may range from -4 to 4, with positive scores indicating an increase in interest. Higher positive scores indicate a larger increase in interest.

Outcome measures

Outcome measures
Measure	Liver Cancer Education n=64 Participants LIVE-R Life Education: A health educator will present participants with a 30-minute PowerPoint presentation containing educational information about liver cancer risk, screening, prevention, symptoms, and treatments, as well as introduce the concept of neighborhood health (e.g., rates of liver cancer and related risk factors in a census tract and how that might influence individual cancer risk).
Change in Interest in Discussing High Liver Cancer Risk With a Healthcare Provider	-1.58 score on a scale Standard Deviation 1.69

PRIMARY outcome

Timeframe: Baseline, 30 minutes

Population: One participant did not answer this item at pre- or post-survey

Patient outcome expectancies for learning about neighborhood health will be measured through a single item asking, on a scale from 0 (not at all) to 10 (very much), whether learning about neighborhood health will help the participant make health decisions. Higher scores indicate more positive expectations. Change in outcomes expectancies is measured by subtracting the baseline score from the post-intervention score. Change scores may range from -10 to 10, with positive scores indicating an increase in outcome expectancies. Higher positive scores indicate a larger increase in expectations.

Outcome measures

Outcome measures
Measure	Liver Cancer Education n=66 Participants LIVE-R Life Education: A health educator will present participants with a 30-minute PowerPoint presentation containing educational information about liver cancer risk, screening, prevention, symptoms, and treatments, as well as introduce the concept of neighborhood health (e.g., rates of liver cancer and related risk factors in a census tract and how that might influence individual cancer risk).
Change in Outcome Expectancies for Learning About Neighborhood Health - Patient Behavior	0.83 score on a scale Standard Deviation 2.58

PRIMARY outcome

Timeframe: Baseline, 30 minutes

Population: Two participants did not respond to this item at pre- or post-survey

Provider outcome expectancies for learning about neighborhood health will be measured through a single item asking, on a scale from 0 (not at all) to 10 (very much), whether learning about neighborhood health will help the participant's healthcare provider make health decisions for them. Higher scores indicate more positive expectations. Change in outcome expectancies is measured by subtracting the baseline score from the post-intervention score. Change scores may range from -10 to 10, with positive scores indicating an increase in outcome expectancies. Higher positive scores indicate a larger increase in expectations.

Outcome measures

Outcome measures
Measure	Liver Cancer Education n=65 Participants LIVE-R Life Education: A health educator will present participants with a 30-minute PowerPoint presentation containing educational information about liver cancer risk, screening, prevention, symptoms, and treatments, as well as introduce the concept of neighborhood health (e.g., rates of liver cancer and related risk factors in a census tract and how that might influence individual cancer risk).
Change in Outcome Expectancies for Learning About Neighborhood Health - Provider Behavior	-0.77 score on a scale Standard Deviation 2.40

PRIMARY outcome

Timeframe: Baseline, 30 minutes

Population: One participants did not answer this item at pre- or post-survey

intentions about communicating with healthcare provider about neighborhood liver cancer will be measured through a single item asking, on a scale from very likely to not at all likely, how likely the participant is to discuss liver cancer in their neighborhood with their healthcare provider over the next 12 months. Scores range from 1 to 5, with higher scores indicating higher likelihood of talking to a healthcare provider. Change in intentions is measured by subtracting the baseline score from the post-intervention score. Change scores may range from -4 to 4, with positive scores indicating an increase in intentions. Higher positive scores indicate a larger increase in intentions.

Outcome measures

Outcome measures
Measure	Liver Cancer Education n=66 Participants LIVE-R Life Education: A health educator will present participants with a 30-minute PowerPoint presentation containing educational information about liver cancer risk, screening, prevention, symptoms, and treatments, as well as introduce the concept of neighborhood health (e.g., rates of liver cancer and related risk factors in a census tract and how that might influence individual cancer risk).
Change in Intentions About Communicating With Healthcare Provider - Neighborhood Prevalence of Liver Cancer	0.79 score on a scale Standard Deviation 1.06

PRIMARY outcome

Timeframe: Baseline, 30 minutes

intentions about communicating with healthcare provider about liver cancer screening will be measured through a single item asking, on a scale from very likely to not at all likely, how likely the participant is to discuss liver cancer screening with their healthcare provider over the next 12 months. Scores range from 1 to 5, with higher scores indicating higher likelihood of talking to a healthcare provider. Change in intentions is measured by subtracting the baseline score from the post-intervention score. Change scores may range from -4 to 4, with positive scores indicating an increase in intentions. Higher positive scores indicate a larger increase in intentions.

Outcome measures

Outcome measures
Measure	Liver Cancer Education n=67 Participants LIVE-R Life Education: A health educator will present participants with a 30-minute PowerPoint presentation containing educational information about liver cancer risk, screening, prevention, symptoms, and treatments, as well as introduce the concept of neighborhood health (e.g., rates of liver cancer and related risk factors in a census tract and how that might influence individual cancer risk).
Change in Intentions About Communicating With Healthcare Provider - Liver Cancer Screening	0.67 score on a scale Standard Deviation 1.24

PRIMARY outcome

Timeframe: Baseline, 30 minutes

Population: Four participants did not respond to this item at pre- or post-survey.

intentions about communicating with healthcare provider about liver cancer risk will be measured through a single item asking, on a scale from very likely to not at all likely, how likely the participant is to discuss their personal risk factors for liver cancer with their healthcare provider over the next 12 months. Scores range from 1 to 5, with higher scores indicating higher likelihood of talking to a healthcare provider. Change in intentions is measured by subtracting the baseline score from the post-intervention score. Change scores may range from -4 to 4, with positive scores indicating an increase in intentions. Higher positive scores indicate a larger increase in intentions.

Outcome measures

Outcome measures
Measure	Liver Cancer Education n=63 Participants LIVE-R Life Education: A health educator will present participants with a 30-minute PowerPoint presentation containing educational information about liver cancer risk, screening, prevention, symptoms, and treatments, as well as introduce the concept of neighborhood health (e.g., rates of liver cancer and related risk factors in a census tract and how that might influence individual cancer risk).
Change in Intentions About Communicating With Healthcare Provider - Liver Cancer Risk	0.35 score on a scale Standard Deviation 0.97

Adverse Events

Liver Cancer Education

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Kristen Sorice

Fox Chase Cancer Center

Phone: 215-214-1433

Email: [email protected]

Results disclosure agreements

Principal investigator is a sponsor employee
Publication restrictions are in place