LTA Assessement Using Aggregometer TA-8V (Stago®)

NCT ID: NCT04269603

Last Updated: 2022-02-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

34 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-11-03

Study Completion Date

2021-01-06

Brief Summary

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Exploring platelet functions requires aggregation tests platelet. The Haematology Laboratory of Hospices Civils de Lyon currently has two new TA-8V plate aggregation automatons® (Stago).

The supplier of these devices does not offer reference values for these tests. There are also no references in the data literature. Therefore reference values must be established from healthy volunteer subjects.

The use of these automatons is subject to the NF (French Standard) EN (European Standard) ISO (International Organization for Standardization) 15189 standard of the COFRAC ( French Accreditation Comity) that requires checking their proper functioning. This audit must be traced in a method validation folder.

Detailed Description

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Conditions

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Healthy Volunteer

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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30 healthy adult volunteers

Healthy adult volunteers without hemorrhagic diathesis.

Group Type OTHER

Take blood (TA-8V (Stago®)

Intervention Type DEVICE

Healthy volunteers will have 3 blood samples at M0, M3 and M6.

Interventions

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Take blood (TA-8V (Stago®)

Healthy volunteers will have 3 blood samples at M0, M3 and M6.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Male or female adults aged between 18 and 70 years
* Weighting more than 50 kg
* Subjects having signed informed consent
* Subjects registered in the French health-care system database

Exclusion Criteria

* Personal history of anemia, thrombopenia, hemorrhagic disease
* Caffeine intake 2 hours prior to blood sampling
* Tobacco intake in the half hour prior to blood sampling
* Use of any drug impacting platelet function
* for antiplatelet agents: at least 10 days prior to blood sampling
* for anti-depressants: at least 10 days prior to blood sampling
* for non-steroid anti-inflammatories: at least 3 days prior to blood sampling
* Refusal to undergo the 3 visits and 3 blood samples of the study
* Refusal to sign the informed consent form
* No registration in the French Health-care system database
* Pregnant women and women who are breastfeeding
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Hospices Civils de Lyon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Clinical Haemostasis Unit/Haematology Laboratory, Groupement Hospitalier Est

Bron, , France

Site Status

Countries

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France

Other Identifiers

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69HCL19_0661

Identifier Type: -

Identifier Source: org_study_id

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