Trial Outcomes & Findings for Education Tools to Support Pediatric Survivor Care (NCT NCT04257058)

NCT ID: NCT04257058

Last Updated: 2025-05-15

Results Overview

Knowledge was assessed at baseline and 2 weeks post-intervention, with the Survivor Care Knowledge scale, that includes 15-item multiple-choice quiz to assess participants' knowledge of the content covered in the electronic educational materials previously provided. Total score ranges from 0-15. Higher score is associated with better outcome.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

89 participants

Primary outcome timeframe

Baseline, 2 weeks post-intervention

Results posted on

2025-05-15

Participant Flow

This study and the data presented below only refers to the young adult survivors and does not include parents. Parents were not enrolled in this study. "Participants" refer to young adult cancer survivors.

Participant milestones

Participant milestones
Measure
Electronic Educational Material
Participants in the trial included young adult survivors of childhood cancer. Participants completed an online pre-test survey via REDCap. After the pre-test is completed, participants review electronic media in REDCap. Study staff confirmed review of material and scheduled a post-test survey to be competed in REDCap two weeks after material is reviewed.
Overall Study
STARTED
89
Overall Study
COMPLETED
58
Overall Study
NOT COMPLETED
31

Reasons for withdrawal

Reasons for withdrawal
Measure
Electronic Educational Material
Participants in the trial included young adult survivors of childhood cancer. Participants completed an online pre-test survey via REDCap. After the pre-test is completed, participants review electronic media in REDCap. Study staff confirmed review of material and scheduled a post-test survey to be competed in REDCap two weeks after material is reviewed.
Overall Study
Lost to Follow-up
31

Baseline Characteristics

Education Tools to Support Pediatric Survivor Care

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Electronic Educational Material
n=89 Participants
Participants in the trial included young adult survivors of childhood cancer. Participants completed an online pre-test survey via REDCap. After the pre-test is completed, participants review electronic media in REDCap. Study staff confirmed review of material and scheduled a post-test survey to be competed in REDCap two weeks after material is reviewed.
Age, Continuous
19.8 years
STANDARD_DEVIATION 1.2 • n=5 Participants
Sex/Gender, Customized
Female
41 Participants
n=5 Participants
Sex/Gender, Customized
Male
45 Participants
n=5 Participants
Sex/Gender, Customized
Non-Binary
3 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
26 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
63 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
2 Participants
n=5 Participants
Race (NIH/OMB)
Asian
4 Participants
n=5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=5 Participants
Race (NIH/OMB)
Black or African American
20 Participants
n=5 Participants
Race (NIH/OMB)
White
56 Participants
n=5 Participants
Race (NIH/OMB)
More than one race
3 Participants
n=5 Participants
Race (NIH/OMB)
Unknown or Not Reported
4 Participants
n=5 Participants
Region of Enrollment
United States
89 participants
n=5 Participants

PRIMARY outcome

Timeframe: Baseline, 2 weeks post-intervention

Population: Total number of participants analyzed per time point include participants that completed the corresponding visit and the specific assessment for this study outcome.

Knowledge was assessed at baseline and 2 weeks post-intervention, with the Survivor Care Knowledge scale, that includes 15-item multiple-choice quiz to assess participants' knowledge of the content covered in the electronic educational materials previously provided. Total score ranges from 0-15. Higher score is associated with better outcome.

Outcome measures

Outcome measures
Measure
Electronic Educational Material
n=89 Participants
Participants in the trial included young adult survivors of childhood cancer. Participants completed an online pre-test survey via REDCap. After the pre-test is completed, participants review electronic media in REDCap. Study staff confirmed review of material and scheduled a post-test survey to be competed in REDCap two weeks after material is reviewed.
Survivor Care Knowledge Scale
Baseline
10.6 score on a scale
Standard Deviation 2.1
Survivor Care Knowledge Scale
2 weeks post-intervention
11.2 score on a scale
Standard Deviation 2.3

SECONDARY outcome

Timeframe: Baseline, 2 weeks post-intervention

Population: Total number of participants analyzed per time point include participants that completed the corresponding visit and the specific assessment for this study outcome.

5-item study adapted Champion Benefits Scale for Mammography Screening. Total score ranges from 5-25. Lower score equals fewer perceived benefits of survivor care.

Outcome measures

Outcome measures
Measure
Electronic Educational Material
n=89 Participants
Participants in the trial included young adult survivors of childhood cancer. Participants completed an online pre-test survey via REDCap. After the pre-test is completed, participants review electronic media in REDCap. Study staff confirmed review of material and scheduled a post-test survey to be competed in REDCap two weeks after material is reviewed.
Benefits for Survivor Care
Baseline
12.6 score on a scale
Standard Deviation 1.9
Benefits for Survivor Care
2 weeks post-intervention
12.9 score on a scale
Standard Deviation 1.8

SECONDARY outcome

Timeframe: Baseline, 2 weeks post-intervention

Population: Total number of participants analyzed per time point include participants that completed the corresponding visit and the specific assessment for this study outcome.

11-item study adapted Champion Barriers Scale for Mammography Screening. Total score ranges from 11-55. Lower score equals fewer perceived barriers to survivor care.

Outcome measures

Outcome measures
Measure
Electronic Educational Material
n=89 Participants
Participants in the trial included young adult survivors of childhood cancer. Participants completed an online pre-test survey via REDCap. After the pre-test is completed, participants review electronic media in REDCap. Study staff confirmed review of material and scheduled a post-test survey to be competed in REDCap two weeks after material is reviewed.
Barriers for Survivor Care
Baseline
20.2 score on a scale
Standard Deviation 5.9
Barriers for Survivor Care
2 weeks post-intervention
19.9 score on a scale
Standard Deviation 5.3

SECONDARY outcome

Timeframe: Baseline, 2 weeks post-intervention

Population: Total number of participants analyzed per time point include participants that completed the corresponding visit and the specific assessment for this study outcome.

3-item study adapted Champion Susceptibility Scale for Mammography Screening. Total score ranges from 3-15. Lower score equals less susceptibility to late effects of treatment.

Outcome measures

Outcome measures
Measure
Electronic Educational Material
n=89 Participants
Participants in the trial included young adult survivors of childhood cancer. Participants completed an online pre-test survey via REDCap. After the pre-test is completed, participants review electronic media in REDCap. Study staff confirmed review of material and scheduled a post-test survey to be competed in REDCap two weeks after material is reviewed.
Perceived Susceptibility for Late Effects
Baseline
9.7 score on a scale
Standard Deviation 3.1
Perceived Susceptibility for Late Effects
2 weeks post-intervention
10.4 score on a scale
Standard Deviation 2.7

SECONDARY outcome

Timeframe: Baseline, 2 weeks post-intervention

Population: Total number of participants analyzed per time point include participants that completed the corresponding visit and the specific assessment for this study outcome.

2-item study adapted Ajzen's Theory of Planned Behavior- Intentions. Total score ranges from 2-14. Lower score equals greater intention to engage in long-term follow-up care.

Outcome measures

Outcome measures
Measure
Electronic Educational Material
n=89 Participants
Participants in the trial included young adult survivors of childhood cancer. Participants completed an online pre-test survey via REDCap. After the pre-test is completed, participants review electronic media in REDCap. Study staff confirmed review of material and scheduled a post-test survey to be competed in REDCap two weeks after material is reviewed.
Intentions for Survivor Care
Baseline
11.8 score on a scale
Standard Deviation 3.4
Intentions for Survivor Care
2 weeks post-intervention
11.4 score on a scale
Standard Deviation 3.4

SECONDARY outcome

Timeframe: Baseline, 2 weeks post-intervention

Population: Total number of participants analyzed per time point include participants that completed the corresponding visit and the specific assessment for this study outcome.

8-item Perceived Health Competence Scale (PHCS). Total score ranges from 8-40. Lower score equals lower perceived health competence.

Outcome measures

Outcome measures
Measure
Electronic Educational Material
n=89 Participants
Participants in the trial included young adult survivors of childhood cancer. Participants completed an online pre-test survey via REDCap. After the pre-test is completed, participants review electronic media in REDCap. Study staff confirmed review of material and scheduled a post-test survey to be competed in REDCap two weeks after material is reviewed.
Change in Perceived Health Competence Scale (PHCS)
Baseline
28.7 score on a scale
Standard Deviation 5.2
Change in Perceived Health Competence Scale (PHCS)
2 weeks post-intervention
27.0 score on a scale
Standard Deviation 5.6

Adverse Events

Electronic Educational Material

Serious events: 2 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Serious adverse events
Measure
Electronic Educational Material
n=89 participants at risk
Participants in the trial included young adult survivors of childhood cancer. Participants completed an online pre-test survey via REDCap. After the pre-test is completed, participants review electronic media in REDCap. Study staff confirmed review of material and scheduled a post-test survey to be competed in REDCap two weeks after material is reviewed.
Nervous system disorders
Stroke
1.1%
1/89 • Number of events 1 • Information on adverse events was collected beginning at the time of the intervention and continuing through the end of the study, at 2 weeks post-intervention.
Cardiac disorders
Myocardial infarction
1.1%
1/89 • Number of events 1 • Information on adverse events was collected beginning at the time of the intervention and continuing through the end of the study, at 2 weeks post-intervention.

Other adverse events

Adverse event data not reported

Additional Information

Dr. Jordan Marchak

Emory University

Phone: 404-727-2293

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place